Results 111 to 120 of about 30,847 (205)

Acute oxidative stress and systemic Nrf2 activation by the ketogenic diet

Neurobiology of Disease, 2010
The mechanisms underlying the efficacy of the ketogenic diet (KD) remain unknown. Recently, we showed that the KD increased glutathione (GSH) biosynthesis.
Julie B. Milder, Li-Ping Liang, Manisha Patel   +2 more
doaj   +1 more source

Dietary Ergothioneine as a Novel Anti‐Aging Nutraceutical: Mechanisms, Bioavailability, and Future Perspectives

Food Frontiers, Volume 7, Issue 3, May 2026.
ABSTRACT Ergothioneine (EGT), a natural thiol derivative, has gained attention as a geroprotective nutraceutical. Preclinical research shows EGT scavenges free radicals, maintains mitochondrial integrity, slows telomere erosion, and regulates proteostasis via autophagy and senescent cell clearance.
Tian‐Tian Tian, Liang Chen, Zhen‐Zhen Dong, Chao Yang   +3 more
wiley   +1 more source

Environmental toxicity, redox signaling and lung inflammation:the role of glutathione [PDF]

, 2009
Glutathione (γ-glutamyl-cysteinyl-glycine, GSH) is the most abundant intracellular antioxidant thiol and is central to redox defense during oxidative stress.
Antonicelli, Aoki, Arfsten, Aruoma, Asti, Ault, Azzi, Bakin, Banhegyi, Banhegyi, Beck, Beeh, Beeh, Bindoli, Biswas, Borgstrom, Braga, Bridgeman, Bunnell, Burgunder, Butterworth, Cantin, Chakravarthi, Chan, Chan, Chen, Chen, Chuang, Church, Colombo, Cotgreave, Cotgreave, Crouch, Crystal, Das, De Benedetto, de Boer, De Caro, Decramer, Decramer, Dekhuijzen, Deleve, Dickinson, Dinkova-Kostova, Drost, Dueholm, Ekberg-Jansson, Erickson, Forman, Galloway, Gerrits, Gillissen, Grandjean, Grigg, Guidot, Haddad, Halliwell, Harju, Harper, Hayes, He, Holdiness, Huang, Hwang, Inci, Irfan Rahman, Ishibashi, Itoh, Janssen, Jardine, Jessop, Jeyapaul, Kang, Kasielski, Katayama, Kidd, Kim, Kinnula, Kinnula, Kinnula, Kinnula, Kobayashi, Kode, Koike, Komatsu, Krzywanski, Kwong, Lee, Lee, Lee, Leonard, Liu, Liu, Lomaestro, Lowry, Lu, Luppi, Mattes, McKone, Meister, Meyer, Miao, Monova, Moran, Moretti, Moretti, Mulcahy, Nakayama, Pacht, Paget, Park, Parmentier, Peltoniemi, Pietarinen-Runtti, Pinkus, Poole, Poole, Rahman, Rahman, Rahman, Rahman, Rahman, Rahman, Rahman, Rahman, Rasmusse, Reddy, Reynaert, Rhee, Roum, Rutkowski, Sadowska, Saibal K. Biswas, Shi, Shin, Siedlinski, Singh, Smith, Stey, Suter, Tanaka, Tian, Tirouvanziam, Tomonari, Trachootham, Tsikas, Tu, Usatyuk, Valko, van der Toorn, Van Schooten, Wakabayashi, Wang, White, Wild, Wood, Wood, Yang, Yang, Yang, Yeh, Zhang, Zhang   +162 more
core   +1 more source

Melatonin improves cardiac function in a mouse model of heart failure with preserved ejection fraction

Redox Biology, 2018
Melatonin has been shown to inhibit myocardial infarction-induced apoptosis, its function in heart failure with preserved ejection fraction (HFpEF) has not been investigated.
Yuan Liu, Li-Na Li, Sen Guo, Xiao-Yan Zhao, Yu-Zhou Liu, Cui Liang, Sheng Tu, Dan Wang, Ling Li, Jian-Zeng Dong, Lu Gao, Hai-Bo Yang   +11 more
doaj   +1 more source

RNA Modifications: Current Understandings and Future Perspectives

MedComm, Volume 7, Issue 5, May 2026.
Types of RNA modification. We have summarized the currently common types of RNA modifications, including ac4C, m6A, m1A, m5C, m3C, m7G, and ψ, and visually characterized their features through structural formulas. The characteristic structures are marked with a background color different from the background color.
Shiyu Xiao, Tingwen Xiang, Chuan Yang, Xiaohua Wang, Gang Huang, Fei Luo, Zhao Xie, Yueqi Chen   +7 more
wiley   +1 more source

Anti-Inflammatory activity of a polyphenolic extract from Arabidopsis thaliana in in vitro and in vivo models of Alzheimer's Disease [PDF]

, 2019
Alzheimer's disease (AD) is the most common neurodegenerative disorder and the primary form of dementia in the elderly. One of the main features of AD is the increase in amyloid-beta (Aβ) peptide production and aggregation, leading to oxidative stress ...
Casale, Assunta Maria, Costantino, Paolo, D'Erme, Maria, Francioso, Antonio, Gazzino, Roberta, Mancini, Patrizia, Mattioli, Roberto, Mosca, Luciana, Piacentini, Lucia, Trovato, Maurizio, Wessjohann, Ludger   +10 more
core   +1 more source

Efficacy of an Innovative Poly-Component Formulation in Counteracting Human Dermal Fibroblast Aging by Influencing Oxidative and Inflammatory Pathways

Biomedicines
Skin aging is characterized by reactive oxygen species (ROS) accumulation, principal players in triggering events associated with aging. Our recent data on the ability of an innovative poly-component formulation (KARISMA Rh Collagen® FACE: K formulation)
Francesca Rosaria Augello, Francesca Lombardi, Alessia Ciafarone, Valeria Ciummo, Serena Altamura, Maurizio Giuliani, Benedetta Cinque, Paola Palumbo   +7 more
doaj   +1 more source

Preoperative Beta‐Hydroxy‐Beta‐Methyl‐Butyrate Supplementation Reduces Mitochondrial Dynamics Proteins and Preserves Hepatic Mitochondrial Function After Partial Hepatectomy in Mice

Acta Physiologica, Volume 242, Issue 5, May 2026.
ABSTRACT Aim The liver exhibits a remarkable regenerative capacity, enabling this organ to maintain homeostasis even after significant injury. However, hepatic regeneration requires sufficient energy to sustain cellular hypertrophy and proliferation, thus ensuring efficient tissue repair.
A. L. Vieira‐da‐Silva, M. V. Esteca, F. A. Silva, I. A. Divino, F. S. Carneiro, E. R. Ropelle, A. S. Torsoni, I. L. Baptista   +7 more
wiley   +1 more source

Effect of oxidative stress on ABC transporters: contribution to epilepsy pharmacoresistance [PDF]

, 2017
Epilepsy is a neurological disorder affecting around 1%-2% of population worldwide and its treatment includes use of antiepileptic drugs to control seizures. Failure to respond to antiepileptic drug therapy is a major clinical problem and over expression
Grewal, G. K., Kanojia, N., Kukal, S., Kukreti, R., Kukreti, S., Saso, L.   +5 more
core   +2 more sources

From Adipose Tissue to Cardiac Repair: Extracellular Vesicles in Cardiovascular Regeneration

Journal of Cellular and Molecular Medicine, Volume 30, Issue 9, May 2026.
ABSTRACT Adipose‐derived extracellular vesicles (ADEVs) secreted by adipose tissue have gained increasing attention due to their regenerative and immunomodulatory properties in cardiovascular diseases. They carry proteins, lipids, and nucleic acids that mediate intercellular communication and influence cardiac pathophysiology. In atherosclerosis, ADEVs
Karolina Ignaczak, Pola Ochocka, Karol Sadowski, Weronika Ploch, Dominika Tomkiel, Mariusz Tomaniak, Wioletta Olejarz   +6 more
wiley   +1 more source