Results 121 to 130 of about 34,540,887 (194)

Black rice anthocyanin extract alleviates cognitive impairment by regulating the MAPK/NF-κB/Nrf2 pathways and modulates gut microbiota dysbacteriosis in D-galactose induced mice

open access: yesFood Science and Human Wellness
Anthocyanins are a plant active ingredient in black rice. Here, we used black rice anthocyanin extract (BRAE) as the object of study and explored its protective mechanism against age-related cognitive decline.
Yaojie Liu   +4 more
doaj   +1 more source

Laminar flow activation of ERK5 protein in vascular endothelium leads to atheroprotective effect via NF-E2-related factor 2 (Nrf2) activation

open access: yes, 2019
Atherosclerosis is often observed in areas where disturbed flow is formed, whereas atheroprotective region is found in areas where steady laminar flow is developed.
임재향
core   +1 more source

Mechanisms underlying the perifocal neuroprotective effect of the Nrf2–ARE signaling pathway after intracranial hemorrhage

open access: yesDrug Design, Development and Therapy, 2015
Xiao-ping Yin,1,2 Zhi-ying Chen,2 Jun Zhou,1 Dan Wu,1,3 Bing Bao2 1Department of Neurology, The Second Affiliated Hospital of Nanchang University, Nanchang, People’s Republic of China; 2Department of Neurology, Affiliated Hospital of Jiujiang ...
Yin XP, Chen ZY, Zhou J, Wu D, Bao B
doaj  

Peroxynitrite induces HO-1 expression via PI3K/Akt-dependent activation of NF-E2-related factor 2 in PC12 cells

open access: yes, 2006
Peroxynitrite is a strong oxidant produced by rapid interaction between superoxide anion and nitric oxide radicals and induces oxidative stress and cell death.
Li, Mei-Hua   +2 more
core   +1 more source

Overexpression of NF-E2 related factor 2 via viral-mediated gene transfer in vivo.

open access: yes, 2005
The transcription factor NF-E2 related factor 2 (Nrf2) is responsible for the upregulation of the cellular anti-oxidant defence system. Upon stimulation by free radicals or reactive oxygen species (ROS), the cytoplasmic-bound Nrf2 translocates to the ...
Imbeault, Sophie
core   +1 more source

Piceatannol ameliorates intestinal barrier dysfunction in urosepsis by modulating the Nrf2/ROS/NF-κB pathway

open access: yesScientific Reports
Urosepsis is a life-threatening condition. Intestinal barrier dysfunction in sepsis drives disease progression and significantly determines mortality.
Xue Gong   +5 more
doaj   +1 more source

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