Results 131 to 140 of about 99,051 (206)

Thrombin Induces COX-2 and PGE₂ Expression via PAR1/PKCalpha/MAPK-Dependent NF-kappaB Activation in Human Tracheal Smooth Muscle Cells. [PDF]

Mediators Inflamm, 2022
Yang CC, Hsiao LD, Shih YF, Hsu CK, Hu CY, Yang CM.   +5 more
europepmc   +1 more source

Transcriptomic Analysis of Fumarate Compounds Identifies Unique Effects of Isosorbide Di-(Methyl Fumarate) on NRF2, NF-kappaB and IRF1 Pathway Genes. [PDF]

Pharmaceuticals (Basel), 2022
Swindell WR, Bojanowski K, Chaudhuri RK.
europepmc   +1 more source

Asiatic Acid Attenuates Osteoporotic Bone Loss in Ovariectomized Mice Through Inhibiting NF-kappaB/MAPK/ Protein Kinase B Signaling Pathway. [PDF]

Front Pharmacol, 2022
Dong M, Zeng J, Yang C, Qiu Y, Wang X.
europepmc   +1 more source

NF-kappaB regulation: the nuclear response.

Journal of cellular and molecular medicine, 2009
Nuclear factor kappaB (NF-kappaB) is an inducible transcription factor that tightly regulates the expression of a large cohort of genes. As a key component of the cellular machinery NF-kappaB is involved in a wide range of biological processes including innate and adaptive immunity, inflammation, cellular stress responses, cell adhesion, apoptosis and ...
Arun K, Mankan, Matthew W, Lawless, Steven G, Gray, Dermot, Kelleher, Ross, McManus   +4 more
openaire   +1 more source

Diosmectite inhibits the interaction between SARS-CoV-2 and human enterocytes by trapping viral particles, thereby preventing NF-kappaB activation and CXCL10 secretion. [PDF]

Sci Rep, 2021
Poeta M, Cioffi V, Buccigrossi V, Nanayakkara M, Baggieri M, Peltrini R, Amoresano A, Magurano F, Guarino A.   +8 more
europepmc   +1 more source

Multi-omics and machine learning identify GBP2 as a key therapeutic target of Qingre Kasen granules in lupus nephritis via NF-kappaB modulation. [PDF]

Ren Fail
Zhu K, Qian R, Huang Z, Hong X, Jiang Q, Xiao B, Chen M, Wen Y, Li S, Chen P, Huang P, Wang Q, Huang F, Li J, Han L.   +14 more
europepmc   +1 more source

Bromodomain-containing protein 4 contributes to chronic postsurgical pain via activating TLR4/NF-kappaB-dependent neuroinflammation. [PDF]

BMC Anesthesiol
Shu R, Li Y, Zhang Z, Zhang X, Guan S, Wang K, Yin Y.   +6 more
europepmc   +1 more source

Helicobacter pylori VacA modulates TRAF1-mediated 4-1BB/NF-kappaB axis to induce host apoptosis and chronic inflammatory damage. [PDF]

Mol Med
Yuan L, Yao S, Qu N, Li X, Yang X, Deng A, Zhang M, Cai T, Liang L, Liu Z, Liu X, Wang F.   +11 more
europepmc   +1 more source

MiR-144-induced KLF2 inhibition and NF-kappaB/CXCR1 activation promote neutrophil extracellular trap-induced transfusion-related acute lung injury. [PDF]

J Cell Mol Med, 2021
Le A, Wu Y, Liu W, Wu C, Hu P, Zou J, Kuang L.   +6 more
europepmc   +1 more source

Targeting NF-kappaB-inducing kinase shapes B-cell homeostasis in myasthenia gravis. [PDF]

J Neuroinflammation
Huang X, Zhang Z, Wang Z, Luo T, Yang M, Guo X, Du X, Ma T, Zhang Y.   +8 more
europepmc   +1 more source