Mechanistic role of the IL-1β/c-Fos/NFATc1 signaling axis in echinococcal infection-promoted osteoclast differentiation and activation in pathological osteolysis: a prospective controlled trial. [PDF]
Ayiheng Y, Mahan W, Xie Z.
europepmc +1 more source
Making Mobile Leaflets: Biomechanical Forces in Atrioventricular Valve Formation. [PDF]
Yang A, Chow RW.
europepmc +1 more source
Nutrients and Metabolites as Signalling Molecules in Osteoclasts. [PDF]
Chandrasekaran K +6 more
europepmc +1 more source
NFATc1 and NFATc2 regulate glucocorticoid resistance in pediatric T-cell acute lymphoblastic leukemia through modulation of cholesterol biosynthesis and the WNT/β-catenin pathway. [PDF]
Veltri G +21 more
europepmc +1 more source
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Critical role of NFATc1 in periapical lesions
International Endodontic Journal, 2010Zhang C, Yang L, Peng B. Critical role of NFATc1 in periapical lesions. International Endodontic Journal, 43, 109–114, 2010.AbstractAim To observe NFATc1 expression in experimental periapical lesions in rats.Methodology Apical periodontitis was induced in Wistar rats by occlusal pulp exposure in mandibular first molar teeth.
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NFATc1: Functions in osteoclasts
International Journal of Biochemistry and Cell Biology, 2010NFATc1 is an important transcription factor which is critical for lineage selection in T-cell differentiation, cardiac valve morphogenesis, lymphatic endothelial development, osteoblast differentiation and osteoclastogenesis. Especially, it is a master regulator of RANKL-induced osteoclast differentiation and plays a pivotal role in osteoclast fusion ...
Qingxiao, Zhao +4 more
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Regulatory mechanism of NFATc1 in RANKL‐induced osteoclast activation [PDF]
NFATc1 is a master regulator of RANKL‐induced osteoclast differentiation and herein we investigate the regulatory mechanism of NFATc1 in osteoclast activation. Inactivation of NFATc1 strongly attenuates RANKL‐induced bone resorption and overexpression of a constitutively active form of NFATc1 in osteoclasts induces formation of actin rings and ...
Insun Song, Jung Ha Kim, Kabsun Kim
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VEGF and RANKL Regulation of NFATc1 in Heart Valve Development [PDF]
Rationale: NFATc1 (nuclear factor of activated T-cells cytoplasmic 1) activity in endocardial cushion (ECC) endothelial cells is required for normal ECC growth and extracellular matrix (ECM) remodeling during heart valve development. Objective:
Katherine E Yutzey
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