Results 141 to 150 of about 37,410 (228)

Mechanically Spatio‐Chimeric Fibrin Assembly Enables Vascular‐Integrated Muscle Reconstruction for Volumetric Muscle Loss Repair

Advanced Materials, Volume 38, Issue 44, 7 August 2026.
SPARC (spatio‐chimeric, plasma‐based, anisotropic, and shear‐responsive construct) that integrates myogenic and vascular microenvironments within a single construct. The dual‐modulus matrix directs aligned myotube formation and endothelial network development, enabling a vascularized muscle implant that seamlessly anastomoses with host tissue and ...
Su Hyun Jung, Minjun Kim, Da‐Yoon Kim, Min Kyu Kim, Sieun Lee, Yoonhee Jin, Joo H. Kang   +6 more
wiley   +1 more source

Multi‐Omics Profiling Reveals Immunomodulatory and Pro‐Regenerative Effects of a Graphene Oxide–Collagen Scaffold in Massive Rotator Cuff Tears

Advanced Science, Volume 13, Issue 44, 7 August 2026.
A graphene oxide/collagen scaffold is developed for chronic massive rotator cuff tear repair. The scaffold improves compressive stability, supports reparative mesenchymal differentiation, and modulates the immune microenvironment. In chronic MRCT models, it reduces muscle degeneration, enhances tendon–bone regeneration, and improves functional recovery,
Renwen Wan, Yechuan Deng, Zixin Hu, Yanwei He, Xinting Feng, Jun Ma, Yisheng Chen, Zhijie Zhao, Jie Mei, Zhiheng Lin, Wei Luo, Zhengyuan Fang, Zhufeng Hu, Kunlun Feng, Xinrong Li, Dan Wu, Bowen Han, James Hoi po Hui, Xuanyong Liu, Chen Chen, Gang Chen, Shiyi Chen, Nirong Bao, Jiajun Qiu, Zhiwen Luo   +24 more
wiley   +1 more source

Impaired cortical actin dynamics via lanosterol-dependent HMG-CoA reductase downregulation mediates IFN-α-induced mast cell stabilization. [PDF]

J Biol Chem
Naskar R, Ye L, Karan S, Hong KS, Yeom Y, Hwang I.   +5 more
europepmc   +1 more source

Lactoferrin Deficiency During Lactation Causes Adult Obesity‐Related Metabolic Disease Through Persistent Adipose Dysfunction Driven by Impaired Adipocyte Development

Advanced Science, Volume 13, Issue 44, 7 August 2026.
Lactational lactoferrin deficiency exerts lasting effects on epididymal adipose tissue development from lactation into adulthood: it impairs adipocyte hyperplasia and induces pathological hypertrophy, resulting in lower body weight yet exacerbated metabolic dysfunction under a high‐fat diet in adulthood.
Qin An, Yunxia Zou, Wenli Wang, Zhimei Cheng, Zhuoxing Zhang, Ruwei Liu, Xiong Wang, Kunlun Huang, Fangrong Ding, Yunping Dai, Qingyong Meng, Yali Zhang   +11 more
wiley   +1 more source

Characteristics and outcomes of patients with pediatric-onset non-mastocytosis mast cell activation disorders: A CEREMAST study. [PDF]

Pediatr Allergy Immunol
Weiss M, Rossignol J, Campeotto F, Foy E, Elbany C, Jaume L, Geroux L, Debeaupuis O, Neuraz A, Bekel L, Lezmi G, Bellon N, Méni C, Livideanu C, Madrange M, Condé D, Agopian J, Michot C, Villard-Truc F, Lachaux A, Greco C, Hadj-Rabia S, Dubreuil P, Hermine O, Bodemer C, Polivka L.   +25 more
europepmc   +1 more source

A Solution for Exosome‐Based Analysis: Surface‐Enhanced Raman Spectroscopy and Artificial Intelligence

Advanced Intelligent Discovery, Volume 2, Issue 4, August 2026.
Exosomes are emerging as powerful biomarkers for disease diagnosis and monitoring. This review highlights the integration of surface‐enhanced Raman spectroscopy with artificial intelligence to enhance molecular fingerprinting of exosomes. Machine learning and deep learning techniques improve spectral interpretation, enabling accurate classification of ...
Munevver Akdeniz, Zakarya Al‐Shaebi, Omer Aydin   +2 more
wiley   +1 more source

Clonal Mast Cell Disorders and Mutation Profile in Adults Initially Presenting with Mast Cell Activation (Anaphylaxis) versus Non-Anaphylactic Presentations: A Joint Allergy-Hematology Cohort. [PDF]

J Asthma Allergy
Pornsuthirat P, Owattanapanich W, Wongsa C, Thongngarm T, Sompornrattanaphan M.   +4 more
europepmc   +1 more source

Gut Microbiota and Ischemic Stroke: From Pre‐Stroke Dysbiosis and Acute‐Phase Changes to Therapeutic Applications

Brain and Behavior, Volume 16, Issue 8, August 2026.
Abstract Purpose Ischemic stroke poses a major global health burden, and growing evidence points to the microbiota–gut–brain axis as an important contributor to stroke pathophysiology and recovery. The purpose of this review is to summarize current knowledge on bidirectional gut‐brain communication in stroke, establishing gut dysbiosis as an upstream ...
Ruihui Weng, Gaolei Dong, Jianxin Tang, Yu Zhao   +3 more
wiley   +1 more source

Fatal reactions to alpha-gal might be due to comorbid mast cell diseases. [PDF]

J Allergy Clin Immunol Pract
Moraczewski J, Stone CA.
europepmc   +1 more source

Oligodendrocyte and Astrocyte Dynamics During Short‐Term Cuprizone Treatment

Brain and Behavior, Volume 16, Issue 8, August 2026.
Early cuprizone exposure (3 days to 1 week) results in the loss of mature oligodendrocytes and a shift in astrocyte subtypes before overt demyelination occurs. A1 astrocytes remained non‐significant; however, A2 astrocytes increased, indicating a protective, pro‐repair astrocyte–oligodendrocyte interaction that may be crucial for therapeutic ...
Lana Frankle, Mercy Oso, Amanda Riley, Riely Tomor, Davi Cecconi Checan, Hannah Lee, Kole Jarzembak, Sarah Sternbach, John Shelestak, Jennifer McDonough, Robert Clements   +10 more
wiley   +1 more source