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Inhibition of nuclear factor-κB activation improves non-nitric oxide-mediated cutaneous microvascular function in reproductive-aged healthy women.

Am J Physiol Heart Circ Physiol
Content VG, Williams AC, Alexander LM.
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Nitric oxide synthase inhibitor L-NG-nitroarginine methyl ester (L-NAME) attenuates remobilization-induced joint inflammation

Nitric Oxide, 2020
Shortly after joint remobilization, inflammation is induced in the joint and aggravates joint contracture via subsequent fibrosis. However, the mechanisms involved in remobilization-induced inflammation are not yet fully understood. We hypothesized that joint immobilization followed by remobilization induces hypoxia/reoxygenation, initiating ...
Akinori, Kaneguchi, Junya, Ozawa, Kengo, Minamimoto, Kaoru, Yamaoka   +3 more
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13. Anti-inflammatory role of L-NG-Nitroarginine Methyl Ester in a chronic model of depression

Brain, Behavior, and Immunity, 2013
The role of nitric oxide (NO) in the neurodegenerative disorders is well illustrated. The close relationship of NO level and the inflammation points out the clinical relevance of NO in depressive disorder. Present study evaluated the neuroprotective role of L-NAME, a NO synthase blocker in chronic restraint hypoxia (CRH) induced depressive behaviour ...
S. DEEP, A. Sharma, I. Baitharu, V. Jain, D. Prasad, S.B. Singh   +5 more
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Circadian-Rhythm-dependent Effects of L-N^G-Nitroarginine Methyl Ester (L-Name) on Morphine-Induced Analgesia

Chronobiology International, 1998
Circadian changes in the interactions between L-NG-nitroarginine methyl ester (L-NAME), a nitric oxide synthase (NOS) inhibitor, and morphine-induced antinociception were investigated by the mouse hot-plate test. Both the basal pain sensitivity and morphine-induced analgesia undergo significant 24 h variations.
Uludag, O, Guney, HZ, Zengil, H, Gorgun, CZ, Hodoglugil, U, Tunctan, B, Abacioglu, N   +6 more
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The influence of L-N G -nitroarginine methyl ester, an inhibitor of nitric oxide synthase, upon the anticonvulsive activity of conventional antiepileptic drugs against maximal electroshock in mice

Journal of Neural Transmission, 1998
NG-Nitro-L-arginine methyl ester (L-NAME, an unspecific nitric oxide synthase inhibitor), applied at 1 and 40 mg/kg, did not influence the electroconvulsive threshold, but impaired the anticonvulsant activity of valproate (at 40 mg/kg) and phenobarbital (at 1 and 40 mg/kg). No effect was observed in the case of carbamazepine and diphenylhydantoin.
K K, Borowicz, R, Starownik, Z, Kleinrok, S J, Czuczwar   +3 more
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Dioscorea prehensilis Ameliorates the Features of Preeclampsia in L-NG-Nitroarginine Methyl Ester (L-NAME) Preeclamptic Model

Tropical Journal of Natural Product Research, 2018
Iyabo Adebisi, Shaibu Bello, Constance Shehu, Musa Abdullahi, Chinenye Ugwah-Oguejiofor, Nnaemeka Ndodo, Mohammed Umar   +6 more
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L-NAME (NG-nitroarginine methyl ester) establishes foetal growth restriction and induces structural and functional lung changes in a multi-insult animal model of bronchopulmonary dysplasia

Molecular pathology and functional genomics
Marnel Greyling, Jaan Toelen, Yannick Regin, Emilie Goffinon   +3 more
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