Results 101 to 110 of about 99,548 (294)
Abstract Objectives Acute cerebral ischemia is characterized by several pathological processes evolving during time, which contribute to the final tissue damage. Secondary processes, such as prolonged inflammatory response, impaired mitochondrial function and oxidative stress, are responsible for the progression of brain injury to the peri‐infarct area,
Fioravante Capone+8 more
wiley +1 more source
Cartilage stem/progenitor cells are activated in osteoarthritis via interleukin-1β/nerve growth factor signaling [PDF]
Introduction: Interleukin-1β (IL-1β) and nerve growth factor (NGF) are key regulators in the pathogenesis of inflammatory arthritis; specifically, IL-1β is involved in tissue degeneration and NGF is involved in joint pain.
Hu, C+6 more
core +3 more sources
Die Verstärkung der Frühphasereaktion des allergischen Asthma bronchiale durch den Nervenwachstumsfaktor NGF [PDF]
Die allergische Frühphasereaktion, ein Kennzeichen des allergischen Asthma bronchiale, wird verursacht durch eine Allergen- und Immunglobulin E (IgE)- abhängige Mediatorfreisetzung aus Mastzellen.
Meents, Nina, Renz, Harald (Prof. Dr.)
core +1 more source
The Next Generation Fornax Survey (NGFS): IV. Mass and Age Bimodality of Nuclear Clusters in the Fornax Core Region [PDF]
We present the analysis of 61 nucleated dwarf galaxies in the central regions ($
arxiv +1 more source
Small Interfering RNA Targeting Nerve Growth Factor Alleviates Allergic Airway Hyperresponsiveness
Airway hyperresponsiveness is the hallmark of allergic asthma and caused by multiple factors. Nerve growth factor (NGF), a neurotrophin, is originally known for regulation of neural circuit development and function.
Yi-Lien Chen+3 more
doaj +1 more source
Uncovering distinct protein-network topologies in heterogeneous cell populations [PDF]
Background: Cell biology research is fundamentally limited by the number of intracellular components, particularly proteins, that can be co-measured in the same cell.
Fermin, Yessica+5 more
core +2 more sources
Dimeric dipeptide mimetic 1st loop of NGF GK-6 (10-6M) activating as phosphatidylinozitol 3-kinase/Akt and mitogen-activated protein kinase MEK/MAPK/ERK) signaling cascades causes PC12 cell differentiation into neuron-like cells. At the same time dimeric
T. A. Antipova+5 more
doaj
Purpose The cyclic AMP response element–binding protein (CREB) and nerve growth factor (NGF) have been proposed as key modulators of brain health and are involved in synaptic plasticity.
Roya. Askari+5 more
doaj +1 more source
Elp1 function in placode‐derived neurons is critical for proper trigeminal ganglion development
Abstract Background The trigeminal nerve is the largest cranial nerve and functions in somatosensation. Cell bodies of this nerve are positioned in the trigeminal ganglion, which arises from the coalescence of neural crest and placode cells. While this dual cellular origin has been known for decades, the molecular mechanisms controlling trigeminal ...
Margaret A. Hines, Lisa A. Taneyhill
wiley +1 more source
The Next Generation Fornax Survey (NGFS): VI. The Alignment of Dwarf Galaxies in The Fornax Cluster [PDF]
Using the photometric data from the Next Generation Fornax Survey, we find a significant radial alignment signal among the Fornax dwarf galaxies. For the first time, we report that the radial alignment signal of nucleated dwarfs is stronger than that of non-nucleated ones at 2.4$\sigma$ confidence level, and the dwarfs located in the outer region ($R ...
arxiv +1 more source