Results 81 to 90 of about 137,103 (391)

Improvement of sciatic nerve regeneration using laminin-binding human NGF-beta. [PDF]

PLoS ONE, 2009
BACKGROUND:Sciatic nerve injuries often cause partial or total loss of motor, sensory and autonomic functions due to the axon discontinuity, degeneration, and eventual death which finally result in substantial functional loss and decreased quality of ...
Wenjie Sun, Changkai Sun, Hui Zhao, Hang Lin, Qianqian Han, Jingyu Wang, Hui Ma, Bing Chen, Zhifeng Xiao, Jianwu Dai   +9 more
doaj   +1 more source

Influence of Quadrato Motor Training on Salivary proNGF and proBDNF [PDF]

, 2019
Previous studies demonstrated exercise-induced modulation of neurotrophins, such as Nerve Growth Factor (NGF) and Brain-Derived Neurotrophic Factor (BDNF).
Ben-Soussan, Tal D., Caserta, Micaela, Venditti, Sabrina, Verdone, Loredana, Vetriani, Valerio   +4 more
core   +2 more sources

Cancer therapy‐induced ototoxicity: Current challenges and emerging management strategies

Animal Models and Experimental Medicine, EarlyView.
This review comprehensively examines the key risk factors for cancer therapy‐induced ototoxicity, including cumulative drug dose, genetic susceptibility, and combined treatment regimens. It highlights current challenges in ototoxicity monitoring, such as insufficient timeliness and limited clinical adoption, and advocates for standardized auditory ...
Yuqi Huang, Baoying Xu, Xinru Chen, Yu Chen, Dehong Yu   +4 more
wiley   +1 more source

TGF-β regulates nerve growth factor expression in a mouse intervertebral disc injury model

BMC Musculoskeletal Disorders, 2021
Background Intervertebral disc (IVD) degeneration is a major cause of low back pain (LBP). Following disc injury, nerve growth factor (NGF) concentrations rise in IVDs, and anti-NGF therapy has been shown to attenuate LBP in humans.
Yuji Yokozeki, Kentaro Uchida, Ayumu Kawakubo, Mitsufumi Nakawaki, Tadashi Okubo, Masayuki Miyagi, Gen Inoue, Makoto Itakura, Hiroyuki Sekiguchi, Masashi Takaso   +9 more
doaj   +1 more source

Uncovering distinct protein-network topologies in heterogeneous cell populations [PDF]

, 2015
Background: Cell biology research is fundamentally limited by the number of intracellular components, particularly proteins, that can be co-measured in the same cell.
Fermin, Yessica, Grecco, Hernan Edgardo, Ickstadt, Katja, Malik Sheriff, Rahuman S., Wieczorek, Jakob, Zamir, Eli   +5 more
core   +2 more sources

Multi‐Method Geophysical Surveys Between and Around the Kerlescan and the Manio Megalithic Alignments in Carnac (Morbihan, France)

Archaeological Prospection, EarlyView.
ABSTRACT The Carnac alignments in Morbihan (France) are among the most famous Neolithic sites of the world. Paradoxically, they have benefited little from a thorough renewal of archaeological data over the past century. There are many reasons for this, but it is mainly because the site has been regarded more as a monument to visit and protect than as ...
Guillaume Bruniaux, Vivien Mathé, Olivier Agogué, Sylvia Lopez, Philippe Paillou, Reena Perschke, Vincent Ard   +6 more
wiley   +1 more source

Comparative analysis activation of post-receptor signal ways by dimeric dipeptide mimetiks of different loops of NGF

Фармакокинетика и Фармакодинамика, 2016
On culture of hippocampal HT-22 cells line it is shown that dimeric dipeptide mimetiks of different Loops of NGF realize their action via specific neurotrophic TrkA-receptor and selective activate post-receptor intracellular signal ways. Mimetiks of 1th (
T. A. Antipova, I. O. Logvinov, S. V. Nikolaev, S. V. Kruglov, A. V. Tarasiuk, P. I. Antipov, T. A. Gudasheva, S. B. Seredenin   +7 more
doaj  

A study on the mnemotropic and antidepressant-like effects of the low-molecular-weight mimetic of nerve growth factor, dipeptide GK-2, in experimental ischemic stroke

Фармакокинетика и Фармакодинамика
Relevance. The nerve growth factor (NGF), possessing neuroprotective and neuroregenerative properties, holds promise for the development of medications for the treatment of post-stroke conditions. At the Federal Research Center for Innovator and Emerging
P. Yu. Povarnina, N. M. Sazonova, D. M. Nikiforov, T. A. Gudasheva, V. L. Dorofeev   +4 more
doaj   +1 more source

Effects of Anti-Nerve Growth Factor Antibody on Symptoms in the NC/Nga Mouse, an Atopic Dermatitis Model

Journal of Pharmacological Sciences, 2005
Nerve growth factor (NGF) is an important substance in the skin, where it can modulate nerve maintenance and repair. However, the direct link between NGF and pruritic disease such as atopic dermatitis is not yet fully understood. To determine whether NGF
Norikazu Takano, Takanobu Sakurai, Michio Kurachi   +2 more
doaj   +1 more source

Die Verstärkung der Frühphasereaktion des allergischen Asthma bronchiale durch den Nervenwachstumsfaktor NGF [PDF]

, 2006
Die allergische Frühphasereaktion, ein Kennzeichen des allergischen Asthma bronchiale, wird verursacht durch eine Allergen- und Immunglobulin E (IgE)- abhängige Mediatorfreisetzung aus Mastzellen.
Meents, Nina, Renz, Harald (Prof. Dr.)
core   +1 more source