Results 101 to 110 of about 137,103 (391)

New opportunities for bioscaffold‐enabled spinal cord injury repair

BMEMat, EarlyView.
Schematic illustration of bioscaffolds for spinal cord injury repair. We summarize the effects of bioscaffold properties on SCI repair, highlight different types of bioscaffolds, various fabrication strategies, and in vivo transformations for the clinical development of SCI‐repairing bioscaffolds.
Xiaoqing Qi, Yicheng Fu, Zhaoliang Su, Li Li, Subrata Chakrabarti, Peng Li, Yilun Wu, Fang Liu, Teng Gao, Zhifeng Dong, Lei Liu, Pei Cao   +11 more
wiley   +1 more source

Ulinastatin Promotes Regeneration of Peripheral Nerves After Sciatic Nerve Injury by Targeting let-7 microRNAs and Enhancing NGF Expression

Drug Design, Development and Therapy, 2020
Jincheng Zhang, Yingqi Zhang, Lei Chen, Zhitao Rao, Yeqing Sun Department of Orthopedics, Tongji Hospital, Tongji University School of Medicine, Shanghai, 200065, People’s Republic of ChinaCorrespondence: Yeqing SunDepartment of Orthopedics Tongji ...
Zhang J, Zhang Y, Chen L, Rao Z, Sun Y
doaj  

Transforming growth factor-β stimulates nerve growth factor production in osteoarthritic synovium

BMC Musculoskeletal Disorders, 2019
Background Nerve growth factor (NGF) contributes to pain in knee osteoarthritis (KOA) patients. Transforming growth factor-beta (TGF-β) stimulates NGF expression in chondrocytes from KOA patients.
Shotaro Takano, Kentaro Uchida, Makoto Itakura, Dai Iwase, Jun Aikawa, Gen Inoue, Manabu Mukai, Masayuki Miyagi, Kosuke Murata, Hiroyuki Sekiguchi, Masashi Takaso   +10 more
doaj   +1 more source

Human fur gene encodes a yeast KEX2-like endoprotease that cleaves pro-beta-NGF in vivo. [PDF]

, 1990
Extracts from BSC-40 cells infected with vaccinia recombinants expressing either the yeast KEX2 prohormone endoprotease or a human structural homologue (fur gene product) contained an elevated level of a membrane-associated endoproteolytic activity that ...
Barr, P, Brake, A, Bresnahan, P, Gibson, H, Leduc, R, Thomas, G, Thomas, L, THORNER, Jeremy W.   +7 more
core   +1 more source

Neuronal differentiation and tissue engineering strategies for central neurous system injury repair

BMEMat, EarlyView.
This review outlines tissue engineering advances for central nervous system (CNS) injury treatment, focusing on three core components: seed cells, inductive factors, and scaffold materials, with evaluation of their respective strengths and limitations. Tissue engineering for CNS injury repair.
Zhuqing Xia, Jinghui Zhang, Na Ren, Shuping Wang, Congcong Zhang, Nik Ahmad Nizam Nik Malek, Wan Hairul Anuar Kamaruddin, Chao Liu, Chunhui Sun, Jingang Wang   +9 more
wiley   +1 more source

Pulsed Electromagnetic Fields: A Novel Attractive Therapeutic Opportunity for Neuroprotection After Acute Cerebral Ischemia

Neuromodulation: Technology at the Neural Interface, EarlyView., 2021
Abstract Objectives Acute cerebral ischemia is characterized by several pathological processes evolving during time, which contribute to the final tissue damage. Secondary processes, such as prolonged inflammatory response, impaired mitochondrial function and oxidative stress, are responsible for the progression of brain injury to the peri‐infarct area,
Fioravante Capone, Simona Salati, Fabrizio Vincenzi, Micaela Liberti, Giorgio Aicardi, Francesca Apollonio, Katia Varani, Ruggero Cadossi, Vincenzo Di Lazzaro   +8 more
wiley   +1 more source

Novel Approach to Design Ultra Wideband Microwave Amplifiers: Normalized Gain Function Method [PDF]

, 2013
In this work, we propose a novel approach called as “Normalized Gain Function (NGF) method” to design low/medium power single stage ultra wide band microwave amplifiers based on linear S parameters of the active device.
Kopru, R., Kuntman, H., Yarman, B. S.
core   +1 more source

Creating well-being: Increased creativity and proNGF decrease following Quadrato Motor Training [PDF]

, 2015
Mind-body practices (MBP) are known to induce electrophysiological and morphological changes, whereas reports related to changes of neurotrophins are surprisingly scarce.
Caterina Pesce, Loredana Verdone, Micaela Caserta, Nicoletta Tocci, Tal Ben Soussan, VENDITTI, Sabrina Donatella Sonia   +5 more
core   +4 more sources

Force stimulation promotes nerve regeneration by restoring cellular energy

BMEMat, EarlyView.
Mechanical stimulation can help nerves regenerate in various ways. We developed two devices (a piezo‐motor‐driven stretching device and a SAW‐based actuator) to apply mechanical stimulation to sciatic nerve and DRG neurons. Our study shows that appropriate mechanical force stimulation can promote regeneration by restoring the energy supply to the ...
Zhe Wang, Chen Cai, Hetao Xie, Yupeng Yang, Lei Li, Nik Ahmad Nizam Nik Malek, Wan Hairul Anuar Kamaruddin, Meiwan Chen, Yuanhua Sang, Bing Ji, Zenan Wang   +10 more
wiley   +1 more source

Dimeric dipeptide mimetic the 1st loop of nerve growth factor of GK-6, which activates PI3K/AKT and MEK/MAPK/ERK, causes a neuronal type differentiation of PC12 cells

Фармакокинетика и Фармакодинамика, 2017
Dimeric dipeptide mimetic 1st loop of NGF GK-6 (10-6M) activating as phosphatidylinozitol 3-kinase/Akt and mitogen-activated protein kinase MEK/MAPK/ERK) signaling cascades causes PC12 cell differentiation into neuron-like cells. At the same time dimeric
T. A. Antipova, S. V. Nikolaev, A. V. Revishchin, E. A. Savchenko, G. V. Pavlova, T. A. Gudasheva   +5 more
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