Peripheral Nerves in Cancer: Regulatory Roles and Therapeutic Strategies. [PDF]
The interaction between cancer cells and peripheral nerves: (1) tumor cells could induce the growth of new neural axons and constructing a neural fiber network within the tumor tissue through secreting nerve growth factors; (2) nerve‐derived bioactive molecules can induce perineural invasion of tumor and regulate the malignant phenotype of tumor, such ...
Fu Y +6 more
europepmc +2 more sources
NAD+ Enhanced on Hearing Recovery in Sudden Sensorineural Hearing Loss: Randomized Controlled Trial
This 2‐year, single‐center, double‐blind study with a small sample size compared NAD+ and control groups in a randomized controlled trial for sudden sensorineural hearing loss (SSNHL). Results showed that NAD+ led to better hearing improvement from 7 days to 3 months and a shorter average recovery time compared to the control group.
Minqian Gao +7 more
wiley +1 more source
Placental‐Derived Connective Tissue Matrix Mediates Murine Recurrent Laryngeal Nerve Regeneration
Placentally derived connective tissue matrix (pd‐CTM) innately contains various neurotrophic, angiogenic, anti‐inflammatory, and tissue remodeling cytokines. In this mouse model of unilateral vocal fold paralysis, we investigate its effects on recurrent laryngeal nerve (RLN) regeneration and reinnervation of the right thyroarytenoid (TA) muscle after ...
Sunjay Anekal +7 more
wiley +1 more source
Nerve growth factor (NGF) and its receptor TrkA —their relations with pain—
Kazue Mizumura, Asako Kubo
openalex +2 more sources
ABSTRACT Aims While many patients with lower urinary tract symptoms (LUTS) improve by treating peripheral causes, a substantial proportion continue to experience symptoms despite apparently successful interventions. Central nervous system (CNS) mechanisms could potentially contribute to persisting symptoms after the initial peripheral cause has been ...
Mathijs M. de Rijk +7 more
wiley +1 more source
Investigating the Role of FGF8 Signaling in Neurogenesis of the Developing Zebrafish Eye [PDF]
In the embryonic zebrafish, the fibroblast growth factor 8a (FGF8) signaling network is essential for proper development and maintenance of retinal ganglion cells (RGCs) as well as the hyaloid vasculature, the vessels that supply the eye with nutrients ...
Flinn, Benjamin A
core +1 more source
Probing the binding mechanism and affinity of tanezumab, a recombinant humanized anti‐NGF monoclonal antibody, using a repertoire of biosensors [PDF]
Yasmina Abdiche +2 more
openalex +1 more source
ABSTRACT Introduction Maintenance of bladder filling and urinary storage at low intravesical pressures is fundamental to minimizing risk to the upper urinary tract. Bladder compliance describes the relationship between the bladder volume and the change in detrusor pressure during the filling phase of urodynamics.
Eric Rovner +5 more
wiley +1 more source
New Advances of Degradable Magnesium‐Based Metal Biomaterials in the Field of Orthopedics
ABSTRACT Based on their outstanding biomechanical properties and superior osteogenic activity, magnesium (Mg) and its alloys have been extensively investigated for their biocompatibility and therapeutic efficacy in treating fractures and bone defects.
Jia‐Nan Yu +8 more
wiley +1 more source
Convergent Effects of Lithium and Valproate on the Expression of Proteins Associated with Large Dense Core Vesicles in NGF-differentiated PC12 Cells [PDF]
Mara L. Cordeiro +2 more
openalex +1 more source

