Results 161 to 170 of about 99,548 (294)
Intelligent Manufacturing for Osteoarthritis Organoids
Cell Proliferation, EarlyView.Overall schematic of intelligent manufacturing in osteoarthritis organoids. Broad overview of the article's structure, outlining the progression from fundamental joint anatomy and OA pathogenesis to organoid construction and, ultimately, to intelligent manufacturing and future prospects.
Xukun Lyu, Jian Wang, Jiacan Su
wiley +1 more source
Developmental Medicine &Child Neurology, EarlyView.Why does infantile epileptic spasms syndrome (IESS) occur with a variety of underlying conditions and why does it respond to adrenocorticotrophin hormone (ACTH)/corticosteroids? Our scoping review summarizes five hypotheses from the literature: gene/epigenetic regulation, stress/HPA axis activation, neuroinflammation/immune function, altered neuronal ...
Emily A. Innes +6 more
wiley +1 more source
Interactions of a neuronal cell line (PC12) with laminin, collagen IV, and fibronectin: identification of integrin-related glycoproteins involved in attachment and process outgrowth. [PDF]
, 1987 Neuronal responses to extracellular matrix (ECM) constituents are likely to play an important role in nervous system development and regeneration. We have studied the interactions of a neuron-like rat pheochromocytoma cell line, PC12, with ECM protein ...
Damsky, CH, Reichardt, LF, Tomaselli, KJ
core
The FEBS Journal, EarlyView.Transient receptor potential cation channel subfamily M member 8 (TRPM8) is a cationic thermosensory channel crucial for cold sensation and menthol response. TRPM8 dysfunction leads to sensory symptoms such as cold allodynia. Targeting TRPM8 is important for treating diseases like peripheral neuropathies and cancer.
Angela Lamberti +9 more
wiley +1 more source
Natural aminosterols inhibit NMDA receptors with low nanomolar potency
The FEBS Journal, EarlyView.Misfunction of N‐methyl‐D‐aspartate (NMDA) receptors is associated with many brain disorders, making them primary targets for drug discovery. Trodusquemine and other natural aminosterols inhibit NMDA receptors with low nanomolar potency through binding to the cell membranes followed by interaction with the channels.
Giulia Fani +9 more
wiley +1 more source
Expression of NGF and NT3 mRNAs in Hippocampal Interneurons Innervated by the GABAergic Septohippocampal Pathway [PDF]
, 1996 Nativitat Rocamora +5 more
openalex +1 more source
Biodiversity finance: Sovereign biodiversity loss drivers and financial stability
Journal of Industrial Ecology, EarlyView.Abstract This study analyzed the impact of sovereign biodiversity risk drivers on financial stability. Using a global dataset covering 2004–2021, I found empirical evidence that the biodiversity risks land use, drought, and freshwater stocks significantly affect the systemic risk measures SRISK and systemic expected shortfall (SES).
Michael Mies
wiley +1 more source
Altered NGF protein levels in different brain areas after immunolesion [PDF]
, 1996 Juan Yu, R.G. Wiley, Regino Perez‐Polo
openalex +1 more source