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While nerve growth factor’s (NGF) role in supporting axon development has been previously explored, there are still many unanswered questions when it comes to its role in axonal degeneration. The following study explores NGF signaling in axonal degeneration.
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Severe sensory and sympathetic neuropathies in mice carrying a disrupted Trk/NGF receptor gene
Nature, 1994Richard J Smeyne +7 more
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Mediation by a CREB family transcription factor of NGF-dependent survival of sympathetic neurons.
Science, 1999A. Riccio +4 more
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A phase1 study of stereotactic gene delivery of AAV2‐NGF for Alzheimer's disease
Alzheimer's & Dementia, 2014M. Rafii +15 more
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Expression and structure of the human NGF receptor.
Cell, 1986Dan Johnson +7 more
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