Results 271 to 280 of about 137,103 (391)
Multi‐target‐directed ligands (MTDLs) offer a promising strategy for Alzheimer's disease by simultaneously modulating amyloid‐β, tau pathology, neuroinflammation, and oxidative stress. This review highlights representative MTDL candidates and their therapeutic potential in addressing the multifactorial nature of AD.
Jaewoon Jung +5 more
wiley +1 more source
RORγ drives non-small cell lung cancer progression by upregulating the NGF signaling. [PDF]
Zeng Y +12 more
europepmc +1 more source
Role of NGF and capsaicin-sensitive innervation in TNBS-induced chronic colonic allodynia
Laure Delafoy +3 more
openalex +1 more source
Proximity Labelling Reveals the Compartmental Proteome of Murine Sensory Neurons
ABSTRACT Introduction Understanding the molecular architecture of peripheral sensory neurons is critical as we pursue novel drug targets against pain and neuropathy. Sensory neurons in the dorsal root ganglion (DRG) show extensive compartmentalization; thus, understanding each compartment—from the peripheral to central terminals—is key to this effort ...
Julia R. Sondermann +9 more
wiley +1 more source
Neurodegeneration, Oxidative Stress, NGF/TrkA/P75<sup>NTR</sup>, and PGE2 Dysregulation Induced by PFOS Single and Repeated Treatment: Partial Protection by T3 and Other Therapeutic Approaches. [PDF]
Moyano P +8 more
europepmc +1 more source
Differential effects of the protein kinase inhibitor K-252a on the in vitro survival of chick embryonie neurons [PDF]
Borasio, Gian Domenico
core
ABSTRACT Background and Objectives Osteoarthritis is a prevalent joint disease causing pain and functional decline, but high variability in patient‐reported treatment outcomes in clinical trials challenges detection of treatment effects. This systematic review aimed to evaluate variability in pain reporting and identify trial characteristics, placebo ...
Jakob M. Bentin +3 more
wiley +1 more source
Impact of digital enhancement on contrast ratio in internal limiting membrane peeling using the NGENUITY 3D visualisation system. [PDF]
Fujioka Y +5 more
europepmc +1 more source

