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Neurotrophin-3: a neurotrophic factor related to NGF and BDNF.
Science, 1990The development and maintenance of the nervous system depends on proteins known as neurotrophic factors. Although the prototypical neurotrophic factor, nerve growth factor (NGF), has been intensively studied for decades, the discovery and ...
P. Maisonpierre +6 more
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NGF and BDNF in pediatrics syndromes
Neuroscience & Biobehavioral Reviews, 2023Neurotrophins (NTs) as nerve growth factor (NGF) and brain-derived neurotrophic factor (BDNF) play multiple roles in different settings including neuronal development, function and survival in both the peripheral and the central nervous systems from early stages.
Ferraguti, Giampiero +9 more
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Psychoneuroendocrinology, 2006
It was July 1983 when, following an almost 10-yearlong discussion with Rita Levi–Montalcini about the physiological role of NGF stored in the submaxillary glands of adult male mice, in collaboration with Luigi Aloe, we decided to attempt a crucial experiment.
Enrico, Alleva, Igor, Branchi
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It was July 1983 when, following an almost 10-yearlong discussion with Rita Levi–Montalcini about the physiological role of NGF stored in the submaxillary glands of adult male mice, in collaboration with Luigi Aloe, we decided to attempt a crucial experiment.
Enrico, Alleva, Igor, Branchi
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Human Idiopathic Epiretinal Membranes Express NGF and NGF Receptors
Retina, 2008Glial cells and fibroblasts (FBs) play a key role in epiretinal membrane (ERM) development and progression. Myofibroblasts (myoFBs), arising from these cells, can lead to the hypertrophic scars and tissue contraction observed in ERMs. Nerve growth factor (NGF) and transforming growth factor-beta1 (TGF-beta1) play a crucial role in FB activities ...
Minchiotti, Simona +6 more
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Experimental Neurology, 1989
Nerve growth factor (NGF) is a well-documented target-derived trophic factor in the peripheral nervous system. Recently, proteins as well as mRNAs for both NGF and its receptor (NGF-R) have been detected in diverse areas in the central nervous system (CNS).
B, Lu +3 more
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Nerve growth factor (NGF) is a well-documented target-derived trophic factor in the peripheral nervous system. Recently, proteins as well as mRNAs for both NGF and its receptor (NGF-R) have been detected in diverse areas in the central nervous system (CNS).
B, Lu +3 more
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Biogenesis and Function of the NGF/TrkA Signaling Endosome
International Review of Cell and Molecular Biology, 2014Target-derived neurotrophin nerve growth factor (NGF) and its receptor TrkA are well known for retrograde signaling to promote survival and innervation of sympathetic and sensory neurons.
M. Caleb Marlin, Guangpu Li
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Journal of the Neurological Sciences, 1995
Nerve growth factor (NGF), initially characterized for its survival and differentiating actions on embryonic sensory and sympathetic neurons, is now known to display a greatly extended spectrum of biological functions. NGF exerts a profound modulatory role on sensory nociceptive nerve physiology during adulthood which appears to correlate with ...
R, Levi-Montalcini +4 more
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Nerve growth factor (NGF), initially characterized for its survival and differentiating actions on embryonic sensory and sympathetic neurons, is now known to display a greatly extended spectrum of biological functions. NGF exerts a profound modulatory role on sensory nociceptive nerve physiology during adulthood which appears to correlate with ...
R, Levi-Montalcini +4 more
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2021
During the development of the nervous system, neurons respond to diffusible cues secreted by target cells. Because such target-derived factors regulate development, maturation, and maintenance of axons as well as somatodendritic compartments, signals initiated at distal axons must be retrogradely transmitted toward cell bodies. Neurotrophins, including
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During the development of the nervous system, neurons respond to diffusible cues secreted by target cells. Because such target-derived factors regulate development, maturation, and maintenance of axons as well as somatodendritic compartments, signals initiated at distal axons must be retrogradely transmitted toward cell bodies. Neurotrophins, including
openaire +2 more sources
Archives italiennes de biologie, 2011
Romantic love is the catalyst behind the spread of the human life. The neurobiology of love embraces the hypothesis that what we call "romantic attachment" or "romantic love" may be at least in part the expression of biological factors. A corollary of this hypothesis states that it is possible to learn much about the nature of human love by studying ...
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Romantic love is the catalyst behind the spread of the human life. The neurobiology of love embraces the hypothesis that what we call "romantic attachment" or "romantic love" may be at least in part the expression of biological factors. A corollary of this hypothesis states that it is possible to learn much about the nature of human love by studying ...
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Molecular Brain Research, 2004
Mice lacking a functional NGF gene (ngf-/- mice) have less than one third of the normal complement of sensory neurons, few sympathetic postganglionic neurons and die shortly after birth. We report here that transgenic expression of NGF under control of the K14 keratin promoter can rescue some elements of the peripheral nervous system and restore normal
Susan M W, Harrison +5 more
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Mice lacking a functional NGF gene (ngf-/- mice) have less than one third of the normal complement of sensory neurons, few sympathetic postganglionic neurons and die shortly after birth. We report here that transgenic expression of NGF under control of the K14 keratin promoter can rescue some elements of the peripheral nervous system and restore normal
Susan M W, Harrison +5 more
openaire +2 more sources