Results 31 to 40 of about 99,548 (294)

Correlation of Nerve Growth Factor and Its Receptors Expression with Perineural Invasion in Early-stage Cervical Cancer

open access: yesZhongliu Fangzhi Yanjiu, 2018
Objective To evaluate the potential association of nerve growth factor (NGF) and its receptors TrkA and p75NRT with perineural invasion(PNI) and other clinicopathological features of early-stage cervical cancer.
LONG Ying   +5 more
doaj   +1 more source

Neuropeptide system parameters in acute herpes zoster

open access: yesИнфекция и иммунитет, 2020
The neuropeptides comprise an important part in the nervous system interacting with endocrine and immune systems. Peptide regulators are responsible for the continuity of communicating elements, which support homeostasis, however, despite abundant ...
S. V. Knysh   +3 more
doaj   +1 more source

Muscle Progenitors Derived from Extraocular Muscles Express Higher Levels of Neurotrophins and their Receptors than other Cranial and Limb Muscles

open access: yesCells, 2020
Extraocular muscles (EOMs) show resistance to muscle dystrophies and sarcopenia. It has been recently demonstrated that they are endowed with different types of myogenic cells, all of which present an outstanding regenerative potential. Neurotrophins are
Génova Carrero-Rojas   +3 more
doaj   +1 more source

Osteocyte Estrogen Receptor β (Ot‐ERβ) Regulates Bone Turnover and Skeletal Adaptive Response to Mechanical Loading Differently in Male and Female Growing and Adult Mice

open access: yesJournal of Bone and Mineral Research, Volume 38, Issue 1, Page 186-197, January 2023., 2023
ABSTRACT Age‐related bone loss is a failure of balanced bone turnover and diminished skeletal mechanoadaptation. Estrogen receptors, ERα and ERβ, play critical roles in osteoprotective regulation activated by estrogen and mechanical signals. Previous studies mainly focused on ERα and showed that osteocyte‐ERα (Ot‐ERα) regulated trabecular, but not ...
Xiaoyu Xu   +6 more
wiley   +1 more source

HU308 Mitigates Osteoarthritis by Stimulating Sox9‐Related Networks of Carbohydrate Metabolism

open access: yesJournal of Bone and Mineral Research, Volume 38, Issue 1, Page 154-170, January 2023., 2023
ABSTRACT Osteoarthritis (OA) is characterized by progressive, irreversible erosion of articular cartilage accompanied by severe pain and immobility. This study aimed to assess the effect and mechanism of action of HU308, a selective cannabinoid receptor type 2 (CB2) agonist, in preventing OA‐related joint damage. To test the assumption that HU308 could
Idan Carmon   +10 more
wiley   +1 more source

Retrograde nerve growth factor signaling modulates tooth mechanical hyperalgesia induced by orthodontic tooth movement via acid-sensing ion channel 3

open access: yesInternational Journal of Oral Science, 2021
Orthodontic tooth movement elicits alveolar bone remodeling and orofacial pain that is manifested by tooth mechanical hyperalgesia. Nerve growth factor (NGF) is upregulated in periodontium and may modulate tooth mechanical hyperalgesia.
Meiya Gao   +11 more
doaj   +1 more source

Nonequilibrium Green's function theory for transport and gain properties of quantum cascade structures [PDF]

open access: yesPhys. Rev. B 66, 245314 (2002), 2002
The transport and gain properties of quantum cascade (QC) structures are investigated using a nonequilibrium Green's function (NGF) theory which includes quantum effects beyond a Boltzmann transport description. In the NGF theory, we include interface roughness, impurity, and electron-phonon scattering processes within a self-consistent Born ...
arxiv   +1 more source

Nerve growth factor receptors in equine synovial membranes vary with osteoarthritic disease severity

open access: yesJournal of Orthopaedic Research, Volume 41, Issue 2, Page 316-324, February 2023., 2023
Abstract Nerve growth factor (NGF) is a neurotrophin that has been implicated in pain signaling, apoptosis, inflammation and proliferation. The resultant effects depend on interaction with two different receptors; tyrosine kinase A (TrkA) and p75NTR. NGF increases in synovial fluid from osteoarthritic joints, and monoclonal antibody therapy is trialed ...
Anna Kendall   +2 more
wiley   +1 more source

A Robust Alternative for Graph Convolutional Neural Networks via Graph Neighborhood Filters [PDF]

open access: yesarXiv, 2021
Graph convolutional neural networks (GCNNs) are popular deep learning architectures that, upon replacing regular convolutions with graph filters (GFs), generalize CNNs to irregular domains. However, classical GFs are prone to numerical errors since they consist of high-order polynomials.
arxiv  

Neurotrophic keratopathy: Update in diagnosis and management

open access: yesIndian Journal of Ophthalmology
The cornea is the most densely sensory innervated tissue in the body. Sensory corneal nerves are essential to maintain ocular surface homeostasis and are involved in the blink reflex, tear production, and the release of trophic factors that are key in ...
Carlos Segundo Font   +1 more
doaj   +1 more source

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