Results 11 to 20 of about 137,103 (391)

NGF, Brain and Behavioral Plasticity [PDF]

open access: yesNeural Plasticity, 2012
Nerve Growth Factor (NGF) was initially studied for its role as a key player in the regulation of peripheral innervations. However, the successive finding of its release in the bloodstream of male mice following aggressive encounters and its presence in the central nervous system led to the hypothesis that variations in brain NGF levels, caused by ...
Alessandra Berry   +2 more
openaire   +4 more sources

Effect of GK-1 NGF Loop 4 Dipeptide Mimetic on tumor growth and metastasis of Lewis lung carcinoma in experiment on male C57BL/6 mice

open access: yesФармакокинетика и Фармакодинамика, 2023
Article describes results of study of antitumor and antimetastatic action of dipeptide mimetic of the nerve growth factor amide N-monosuccinyl-L-glutamyl-L-lysine (compound GK-1) in comparison with gemcitabine. Two injections of gemcitabine in total dose
L. P. Kovalenko   +3 more
doaj   +1 more source

The Role of DHEA, NGF, and ADAMTS5 Pathways in Osteoarthritis and Current Developments

open access: yesBagcilar Medical Bulletin, 2023
Degenerative joint disease is a condition that affects joints and is commonly referred to as osteoarthritis (OA). This form of arthritis is most prevalent among women and tends to become more frequent as people age.
Duygu Sarı Ak   +5 more
doaj   +1 more source

Protective effects of Derinat, a nucleotide-based drug, on experimental traumatic brain injury, and its cellular mechanisms

open access: yesМедицинская иммунология, 2021
Traumatic brain injury is the most common cause of death and disability in young people including sport athletes and soldiers, people under 45 years of age in the industrialized countries, representing a growing health problem in developing countries, as
E. A. Korneva   +4 more
doaj   +1 more source

Innovative Therapy for Alzheimer’s Disease-With Focus on Biodelivery of NGF

open access: yesFrontiers in Neuroscience, 2019
Alzheimer’s disease (AD) is a progressive neurodegenerative disorder associated with abnormal protein modification, inflammation and memory impairment. Aggregated amyloid beta (Aβ) and phosphorylated tau proteins are medical diagnostic features.
Sumonto Mitra   +2 more
semanticscholar   +1 more source

NGF and Its Receptors in the Regulation of Inflammatory Response

open access: yesInternational Journal of Molecular Sciences, 2017
There is growing interest in the complex relationship between the nervous and immune systems and how its alteration can affect homeostasis and result in the development of inflammatory diseases.
G. Minnone   +2 more
semanticscholar   +1 more source

Gold nanoclusters-assisted delivery of NGF siRNA for effective treatment of pancreatic cancer

open access: yesNature Communications, 2017
Pancreatic cancer is one of the deadliest human cancers, whose progression is highly dependent on the nervous microenvironment. The suppression of gene expression of nerve growth factor (NGF) may have great potential in pancreatic cancer treatment.
Yifeng Lei   +9 more
semanticscholar   +1 more source

The Brain NGF Metabolic Pathway in Health and in Alzheimer’s Pathology

open access: yesFrontiers in Neuroscience, 2019
Emerging research has re-emphasized the role of the cortical cholinergic system in the symptomology and progression of Alzheimer’s disease (AD). Basal forebrain (BF) cholinergic nuclei depend on target-derived NGF for survival during development and for ...
A. Cuello, R. Pentz, Hélène Hall
semanticscholar   +1 more source

Pathogenetic role of the pain threshold Hypothetical therapeutic perspectives based on the use of drugs to elevate it

open access: yesPathos, 2023
The pain threshold determines the extent of pain perception, and in some cases, its manifestation. Therefore, it is important in certain situations to increase the pain threshold. Measuring the pain threshold is challenging due to its approximate nature.
Guido Orlandini
doaj  

Low Energy Processes Associated with Spontaneously Broken N=2 Supersymmetry [PDF]

open access: yes, 2009
We consider low energy processes described by the N=2 supercurrent on its partially (to N=1) and spontaneously broken vacuum and the attendant Nambu-Goldstone fermion (NGF), which the presence of the electric and magnetic Fayet-Iliopoulos (FI) terms is ...
Adler   +80 more
core   +3 more sources

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