Results 31 to 40 of about 94,176 (342)
A novel anti-NGF PEGylated Fab’ provides analgesia with lower risk of adverse effects
mAbs, 2023 Nerve growth factor (NGF) has emerged as a key driver of pain perception in several chronic pain conditions, including osteoarthritis (OA), and plays an important role in the generation and survival of neurons.
Yukari Koya +8 more
doaj +1 more source
Acta Biomaterialia, 2015 Objective Nerve growth factor (NGF) has potential in spinal cord injury (SCI) therapy, but limited by the poor physicochemical stability and low ability to cross the blood spinal cord barrier.
Ying-zheng Zhao +9 more
semanticscholar +1 more source
Herpes simplex virus-1 entry into cells mediated by a novel member of the TNF/NGF receptor family.
Cell, 1996 We identified and cloned a cellular mediator of herpes simplex virus (HSV) entry. Hamster and swine cells resistant to viral entry became susceptible upon expression of a human cDNA encoding this protein, designated HVEM (for herpesvirus entry mediator).
R. Montgomery +3 more
semanticscholar +1 more source
, 2017 Poly(epsilon-caprolactone) (PCL) scaffolds functionalized by grafting nerve growth factor (NGF) and Asp-Arg-Gly-Asp (GRGD)(PCL-NGF/GRGD) for neural tissue engineering.
Chung, Tze-Wen;Lai, Dar-Ming;Chen, Shin-Der;Lin, Ya-I +1 more
core +1 more source
Adenosine triphosphate as a modulator of protein interactions and stability
FEBS Open Bio, EarlyView.ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley +1 more source
Scientific ReportsSustainable carboxymethyl cellulose/graphene oxide (GO) aerogels were fabricated via epichlorohydrin cross-linking and ice-templating for effective methylene blue (MB) removal from aqueous solutions. The synergistic effects of GO loading (1, 3, and 5 wt%)
Soon Wan Kweon +5 more
doaj +1 more source
Advancing Human Skin Equivalents: The Crucial Role of Neurovascular Integration
Advanced Healthcare Materials, EarlyView.This review discusses the importance of integrating vascular and peripheral nerve systems into human skin equivalents (HSEs) to better recapitulate native skin physiology. Recent advances in vascularized, innervated, and neurovascularized HSEs are highlighted, together with emerging bioengineering strategies, current challenges, and future ...
Hao Wu +4 more
wiley +1 more source
Cells, 2020 Extraocular muscles (EOMs) show resistance to muscle dystrophies and sarcopenia. It has been recently demonstrated that they are endowed with different types of myogenic cells, all of which present an outstanding regenerative potential. Neurotrophins are
Génova Carrero-Rojas +3 more
doaj +1 more source
, 2021 Alzheimer's disease (AD), one of the most common causes of dementia in elderly people, is characterized by progressive impairment in cognitive function, early degeneration of basal forebrain cholinergic neurons (BFCNs), abnormal metabolism of the amyloid
Canu N., Ruberti F., Triaca V.
core +1 more source
Bioengineered Interfaces for Peripheral Nerve Sensory Restoration
Advanced Materials, EarlyView.Half of amputees abandon their prosthetics for lack of feeling. This review charts the full path from peripheral nerve injury to restored sensation, through surgical, regenerative, noninvasive, and implanted approaches, and shows how injury type and interface material properties determine which strategy can deliver naturalistic feedback, and why ...
Sydney Swedick +4 more
wiley +1 more source