Results 31 to 40 of about 137,103 (391)

Neuropeptide system parameters in acute herpes zoster

Инфекция и иммунитет, 2020
The neuropeptides comprise an important part in the nervous system interacting with endocrine and immune systems. Peptide regulators are responsible for the continuity of communicating elements, which support homeostasis, however, despite abundant ...
S. V. Knysh, E. V. Markelova, A. I. Simakova, A. V. Karaulov   +3 more
doaj   +1 more source

ProNGF-p75NTR axis plays a proinflammatory role in inflamed joints. A novel pathogenic mechanism in chronic arthritis [PDF]

, 2017
To identify the role of mature nerve growth factor (mNGF), its immature form proNGF and their receptors in arthritis ...
Benedetti, Fabrizio De, Bracci-laudiero, Luisa, Caiello, Ivan, Magni-manzoni, Silvia, Manni, Luigi, Manzo, Antonio, Marafon, Denise Pires, Minnone, Gaetana, Prencipe, Giusi, Soligo, Marzia   +9 more
core   +1 more source

Using NGF heparin-poloxamer thermosensitive hydrogels to enhance the nerve regeneration for spinal cord injury

Acta Biomaterialia, 2015
Objective Nerve growth factor (NGF) has potential in spinal cord injury (SCI) therapy, but limited by the poor physicochemical stability and low ability to cross the blood spinal cord barrier.
Ying-zheng Zhao, Xi Jiang, Jian Xiao, Qian Lin, Wen-Ze Yu, Fu-Rong Tian, Kaili Mao, Wei Yang, H. Wong, Cui-tao Lu   +9 more
semanticscholar   +1 more source

Muscle Progenitors Derived from Extraocular Muscles Express Higher Levels of Neurotrophins and their Receptors than other Cranial and Limb Muscles

Cells, 2020
Extraocular muscles (EOMs) show resistance to muscle dystrophies and sarcopenia. It has been recently demonstrated that they are endowed with different types of myogenic cells, all of which present an outstanding regenerative potential. Neurotrophins are
Génova Carrero-Rojas, Beatriz Benítez-Temiño, Angel M. Pastor, Mª América Davis López de Carrizosa   +3 more
doaj   +1 more source

Retrograde nerve growth factor signaling modulates tooth mechanical hyperalgesia induced by orthodontic tooth movement via acid-sensing ion channel 3

International Journal of Oral Science, 2021
Orthodontic tooth movement elicits alveolar bone remodeling and orofacial pain that is manifested by tooth mechanical hyperalgesia. Nerve growth factor (NGF) is upregulated in periodontium and may modulate tooth mechanical hyperalgesia.
Meiya Gao, Xinyu Yan, Yanzhu Lu, Linghuan Ren, Shizhen Zhang, Xiaoqi Zhang, Qianyun Kuang, Lu Liu, Jing Zhou, Yan Wang, Wenli Lai, Hu Long   +11 more
doaj   +1 more source

Neurotrophic keratopathy: Update in diagnosis and management

Indian Journal of Ophthalmology
The cornea is the most densely sensory innervated tissue in the body. Sensory corneal nerves are essential to maintain ocular surface homeostasis and are involved in the blink reflex, tear production, and the release of trophic factors that are key in ...
Carlos Segundo Font, Maria Soledad Cortina   +1 more
doaj   +1 more source

Electroacupuncture Alleviates KOA-Induced Pain and Cartilage Degeneration via NGF/TrkA Pathway. [PDF]

J Pain Res
Fu Y, Lin L, Chen W, Shi G, Li HP, Tu JF, Liu CZ.   +6 more
europepmc   +2 more sources

Synergistic effects of graphene oxide loading and particle size in ice-templated carboxymethyl cellulose–based aerogels on dye removal

Scientific Reports
Sustainable carboxymethyl cellulose/graphene oxide (GO) aerogels were fabricated via epichlorohydrin cross-linking and ice-templating for effective methylene blue (MB) removal from aqueous solutions. The synergistic effects of GO loading (1, 3, and 5 wt%)
Soon Wan Kweon, Dae-Hyun Jang, Tai Ju Lee, Heoug-Yoon Kweon, Heon-Sang Kim, Hyoung Jin Kim   +5 more
doaj   +1 more source

Research of neuroprotective properties of TrkA-receptor agonist GK-2 on model of oxidative stress in human vascular endothelial cells (HUVEC)

Фармакокинетика и Фармакодинамика, 2019
Oxidative stress resulted to decrease in cells viability compared to the control (78 ± 5 % and 100 ± 6 %, respectively, р < 0,05). GK-2 and NGF prevented H2O2-induced HUVEC cells damages (95 ± 3 % for HA-2 and 97 ± 4 % for NGF vs.
T. A. Antipova, S. V. Nikolaev, S. A. Kryzhanovsky, E. S. Pekeldina   +3 more
doaj   +1 more source

Prediction of relative change in free nerve growth factor following subcutaneous administration of tanezumab, a novel monoclonal antibody to nerve growth factor

CPT: Pharmacometrics & Systems Pharmacology, 2023
Tanezumab is a monoclonal antibody against nerve growth factor (NGF). We investigated tanezumab pharmacokinetic (PK)‐NGF relationships and predicted the extent of systemic free NGF suppression with target‐mediated drug disposition (TMDD) modeling using ...
Satoshi Shoji, Akiyuki Suzuki, Parya Nouri, Chun‐Hua Cai, Puneet Gaitonde, Scott Marshall   +5 more
doaj   +1 more source