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Медицинская иммунология, 2021 Traumatic brain injury is the most common cause of death and disability in young people including sport athletes and soldiers, people under 45 years of age in the industrialized countries, representing a growing health problem in developing countries, as
E. A. Korneva +4 more
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Gold nanoclusters-assisted delivery of NGF siRNA for effective treatment of pancreatic cancer
Nature Communications, 2017 Pancreatic cancer is one of the deadliest human cancers, whose progression is highly dependent on the nervous microenvironment. The suppression of gene expression of nerve growth factor (NGF) may have great potential in pancreatic cancer treatment.
Yifeng Lei +9 more
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Cell Reports, 2016 SUMMARY Developing tissues dictate the amount and type of innervation they require by secreting neurotrophins, which promote neuronal survival by activating distinct tyrosine kinase receptors.
R. Tomlinson +11 more
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In vivo function of NGF/TrkA signaling in the cholinergic neurons of the murine basal forebrain [PDF]
, 2005 The neurotrophins are a family of secreted proteins that potently regulate diverse neuronal responses. The neurotrophin nerve growth factor (NGF) and its receptors TrkA and p75 are well characterized to control survival, differentiation and function of ...
Mueller, Markus
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The involvement of BDNF, NGF and GDNF in aging and Alzheimer's disease.
Aging and Disease, 2015 Aging is a normal physiological process accompanied by cognitive decline. This aging process has been the primary risk factor for development of aging-related diseases such as Alzheimer's disease (AD).
J. Budni +4 more
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Pathos, 2023 The pain threshold determines the extent of pain perception, and in some cases, its manifestation. Therefore, it is important in certain situations to increase the pain threshold. Measuring the pain threshold is challenging due to its approximate nature.
Guido Orlandini
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Zhongliu Fangzhi Yanjiu, 2018 Objective To evaluate the potential association of nerve growth factor (NGF) and its receptors TrkA and p75NRT with perineural invasion(PNI) and other clinicopathological features of early-stage cervical cancer.
LONG Ying +5 more
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Current Issues in Pharmacy and Medical Sciences, 2020 Ulcers and slow wound healing are common in diabetic polyneuropathy (DP), as well as shooting or burning pain, sensitivity to touch or lack of sensitivity, low oxygenation of nerve tissue, conductivity disorders and various vascular disorders.
Nikitina Nataliia +6 more
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β-NGF and its low-affinity receptor (p75ᴸᴺᴳᶠᴿ) in benign prostatic hyperplasia and adenocarcinoma of the prostate [PDF]
, 1999 The proteinaceous hormone 6-nerve growth factor (B-NGF) acts on plasmalemmal receptors to cause neural differentiation in uncommitted cells, and growth and maintenance of neural processes.
Paul, Alan Burnett
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Neuropeptide system parameters in acute herpes zoster
Инфекция и иммунитет, 2020 The neuropeptides comprise an important part in the nervous system interacting with endocrine and immune systems. Peptide regulators are responsible for the continuity of communicating elements, which support homeostasis, however, despite abundant ...
S. V. Knysh +3 more
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