Characterisation of ERK distribution and activity in rat pheochromocytoma cells : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Molecular Biology at Massey University [PDF]
, 1998 Nerve growth factor (NGF) binds to the NGF receptor, TrkA, at the tips of nerve cell axons, sending a signal that prevents programmed cell death and causes survival, growth, and differentiation of the nerve cell.
MacCormick, Matthew Edgar
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Aptamer‐Based Delivery Systems for VEGF and NGF Modulation in Ocular Therapies
Advanced Healthcare Materials, EarlyView.Aptamer‐based delivery systems targeting NGF and VEGF hold significant potential for precise and sustained treatment of complex diseases affecting both the anterior and posterior segments of the eye. This review critically summarizes current strategies for NGF and VEGF delivery as well as VEGF sequestration, providing a clinical perspective on how ...
Nadine Best +5 more
wiley +1 more source
Nerve growth factor nonresponsive pheochromocytoma cells: altered internalization results in signaling dysfunction. [PDF]
, 1992 Variant rat pheochromocytoma (PC12) cells which fail to respond to nerve growth factor (NGF) (PC12nnr5) (Green, S. H., R. E. Rydel, J. L. Connoly, and L. A. Greene. 1986. J. Cell Biol. 102:830-843) bind NGF at both high and low affinity sites.
Bradshaw, RA, Eveleth, DD
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Nonequilibrium Green's function theory for transport and gain properties of quantum cascade structures [PDF]
, 2002 The transport and gain properties of quantum cascade (QC) structures are investigated using a nonequilibrium Green's function (NGF) theory which includes quantum effects beyond a Boltzmann transport description.
A. Wacker +22 more
core +1 more source
Herpes simplex virus-1 entry into cells mediated by a novel member of the TNF/NGF receptor family.
Cell, 1996 We identified and cloned a cellular mediator of herpes simplex virus (HSV) entry. Hamster and swine cells resistant to viral entry became susceptible upon expression of a human cDNA encoding this protein, designated HVEM (for herpesvirus entry mediator).
R. Montgomery +3 more
semanticscholar +1 more source
Conductive Hydrogels for Exogenous Sensing and Cell Fate Control
Advanced Materials, EarlyView.We engineer electrically conductive hydrogels by combining sulfated glycosaminoglycans with semiconducting polymers. These hydrogels bind bioactive proteins, including growth factors, whose release or retention can be modulated by low‐voltage stimulation. The hydrogels are also integrated as 3D channels in organic electrochemical transistors as part of
Teuku Fawzul Akbar +15 more
wiley +1 more source
Changes of Nerve Growth Factor Synthesis in Nonneuronal Cells in Response to Sciatic Nerve Transection [PDF]
, 1987 The intact sciatic nerve contains levels of nerve growth factor (NGF) that are comparable to those of densely innervated peripheral target tissues of NGF-responsive (sympathetic and sensory) neurons.
Bandtlow, Christine +3 more
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Effect of recombinant human nerve growth factor eye drops in patients with dry eye: a phase IIa, open label, multiple-dose study [PDF]
, 2019 Background: Dry eye disease (DED) affects more than 14% of the elderly population causing decrease of quality of life, high costs and vision impairment.
Allegretti, M. +7 more
core +1 more source
Cell Adhesion by Design: Engineering Tissue Culture Scaffolds With Adhesion Cues
Advanced Materials Interfaces, EarlyView.ABSTRACT In scaffold‐based tissue engineering, the matrix should provide adequate adhesion cues for cell attachment, spreading, and function. Given the multitude of adhesion receptors and the diversity of scaffolds, there are many approaches to render scaffolds adhesive, even though they are not all equivalent.
Dalia Dranseike +3 more
wiley +1 more source
Association of NGF receptors with membrane rafts in PC12 cells : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Biochemistry at Massey University [PDF]
, 2001 Nerve Growth Factor (NGF) signal transduction is involved in the survival, differentiation and maintenance of neurons through the receptors TrkA and p75NTR. These receptors activate downstream protein kinase cascades that regulate cell survival.
Clements, Shona Marie
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