Effects of a synthetic bioactive peptide on neurite growth and nerve growth factor release in chondroitin sulfate hydrogels. [PDF]
, 2011 Previous work has revealed robust dorsal root ganglia neurite growth in hydrogels of chondroitin sulfate. In the current work, it was determined whether addition of a synthetic bioactive peptide could augment neurite growth in these matrices via enhanced
Beier, Brooke L +3 more
core +1 more source
The Next Generation Fornax Survey (NGFS): III. Revealing the Spatial Substructure of the Dwarf Galaxy Population inside half of Fornax's Virial Radius [PDF]
, 2018 We report the discovery of 271 previously undetected dwarf galaxies in the outer Fornax cluster regions at radii $r_{\rm vir}/4<\!r\!
arxiv +1 more source
The Reconstruction of Peripheral Auditory Circuit: Recent Advances and Future Challenges
Advanced Science, EarlyView.This paper summarizes the potential of biomaterials, stem cells, and gene editing technologies in the regeneration of inner ear hair cells, spiral ganglion neurons, and inner ear organoids. Challenges and potential developments are discussed and explored.
Zhe Li +3 more
wiley +1 more source
Hypothesis review: Alzheimer's overture guidelines
Brain Pathology, Volume 33, Issue 1, January 2023., 2023 Brain aging with ADNC and sporadic Alzheimer's disease (sAD) form a prevalent continuum unique to humans. Molecular changes affecting cell membranes, cytoskeleton, synapses, lipid and protein metabolism, energy metabolism, neuroinflammation, cell cycle, astrocytes, microglia, and blood vessels precede and occur in parallel with early ADNC; and they are
Isidro Ferrer
wiley +1 more source
Improvement of sciatic nerve regeneration using laminin-binding human NGF-beta. [PDF]
PLoS ONE, 2009 BACKGROUND:Sciatic nerve injuries often cause partial or total loss of motor, sensory and autonomic functions due to the axon discontinuity, degeneration, and eventual death which finally result in substantial functional loss and decreased quality of ...
Wenjie Sun +9 more
doaj +1 more source
High Fat Low Carbohydrate Diet Is Linked to CNS Autoimmunity Protection
Advanced Science, EarlyView.Mapping global epidemiological data to macronutrient supply reveals high carbohydrate, in contrast to high fat supply, associates with increased multiple sclerosis (MS) prevalence and incidence. This is confirmed in a mouse MS model, experimental autoimmune encephalomyelitis (EAE), using isocaloric diets: a high carbohydrate diet aggravates, a high ...
Duan Ni +15 more
wiley +1 more source
Simultaneous effect of aerobic exercise and nanocurcumin supplementation on the expression of BDNF and NGF genes in rats with brain tumor [PDF]
Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i ĪlāmIntroduction: Increased nerve growth factor (NGF) and brain-derived neurotrophic factor (BDNF) signaling in neuroblastoma cells may represent an autocrine system to support cancer growth, invasion, and metastasis.
Salmah Mohamadi +3 more
doaj
Фармакокинетика и Фармакодинамика, 2019 Oxidative stress resulted to decrease in cells viability compared to the control (78 ± 5 % and 100 ± 6 %, respectively, р < 0,05). GK-2 and NGF prevented H2O2-induced HUVEC cells damages (95 ± 3 % for HA-2 and 97 ± 4 % for NGF vs.
T. A. Antipova +3 more
doaj +1 more source
TGF-β regulates nerve growth factor expression in a mouse intervertebral disc injury model
BMC Musculoskeletal Disorders, 2021 Background Intervertebral disc (IVD) degeneration is a major cause of low back pain (LBP). Following disc injury, nerve growth factor (NGF) concentrations rise in IVDs, and anti-NGF therapy has been shown to attenuate LBP in humans.
Yuji Yokozeki +9 more
doaj +1 more source
NGF, TrkA-P and neuroprotection after a hypoxic event in the developing central nervous system [PDF]
, 2018 A decrease in the concentration of oxygen in the blood and tissues (hypoxia) produces important, sometimes irreversible, damages in the central nervous system (CNS) both during development and also postnatally.
Bogetti, María Eugenia +4 more
core +1 more source