Results 41 to 50 of about 91,799 (300)

Niacin-induced clotting factor synthesis deficiency with coagulopathy [PDF]

open access: yes, 1992
Although coagulopathy is a well-known complication of severe niacin- induced hepatotoxic reaction, it is not found in patients with minimal aminotransferase level elevations.
Dearing, Brian D.   +3 more
core   +1 more source

Niacin noncompetitively inhibits DGAT2 but not DGAT1 activity in HepG2 cells1

open access: yesJournal of Lipid Research, 2004
Niacin is a widely used lipid-regulating agent in dyslipidemic patients. Previously, we have shown that niacin inhibits triacylglycerol synthesis.
Shobha H. Ganji   +5 more
doaj   +1 more source

Structural and Energetic Insights Into the Interaction of Niacin With the GPR109A Receptor

open access: yesBioinformatics and Biology Insights, 2021
The transmembrane G-protein coupled receptor GPR109A has been previously shown to function as a receptor for niacin in mediating antilipolytic effects.
Kiran Kumar Adepu   +3 more
doaj   +1 more source

Low and deficient niacin status and pellagra are endemic in postwar Angola [PDF]

open access: yes, 2007
BACKGROUND: Outbreaks of pellagra were documented during the civil war in Angola, but no contemporary data on the incidence of pellagra or the prevalence of niacin deficiency were available.
Cheung, E   +6 more
core   +2 more sources

AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury

open access: yes, 2022
Hepatology, EarlyView.
Robert J. Fontana   +6 more
wiley   +1 more source

Differential Effects of Lipid-lowering Drugs in Modulating Morphology of Cholesterol Particles. [PDF]

open access: yes, 2017
Treatment of dyslipidemia patients with lipid-lowering drugs leads to a significant reduction in low-density lipoproteins (LDL) level and a low to moderate level of increase in high-density lipoprotein (HDL) cholesterol in plasma.
Alderete, Benjamin   +7 more
core   +1 more source

Association between Daily Niacin Intake and Glaucoma: National Health and Nutrition Examination Survey

open access: yesNutrients, 2021
Background and Aims: To determine the relationship between dietary intake of niacin and glaucoma using the data from the 2005 to 2008 National Health and Nutrition Examination Survey (NHANES). Methods: Subjects aged 40 years and older who participated in
Teerajet Taechameekietichai   +3 more
semanticscholar   +1 more source

EFFECT OF LOW-DOSE NIACIN ON DYSLIPIDEMIA, SERUM PHOSPHORUS LEVELS AND ADVERSE EFFECTS IN PATIENTS WITH CHRONIC KIDNEY DISEASE

open access: yesKidney Research and Clinical Practice, 2012
Niacin supplementation improves dyslipidemia and lowers serum phosphorus levels in chronic kidney disease (CKD) patients. However, its adverse effects, including hot flusing, hinder the administration of niacin.
Won Suk An, Hyo Jin Kang, Ki Hyun Kim
doaj   +1 more source

Whole blood NAD and NADP concentrations are not depressed in subjects with clinical pellagra [PDF]

open access: yes, 2007
Population surveys for niacin deficiency are normally based on clinical signs or on biochemical measurements of urinary niacin metabolites. Status may also be determined by measurement of whole blood NAD and NADP concentrations. To compare these methods,
Cheung, E   +5 more
core   +2 more sources

Effect of Niacin on Growth Performance, Intestinal Morphology, Mucosal Immunity and Microbiota Composition in Weaned Piglets

open access: yesAnimals, 2021
Simple Summary The protective effect of niacin on growth performance and gut health of weaned piglets and the underlying mechanism remains unclear despite it being a common additive in pig diets.
Shilong Liu   +7 more
semanticscholar   +1 more source

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