Results 21 to 30 of about 33,803 (193)

Low-Dose Niacin Supplementation Improves Motor Function in US Veterans with Parkinson’s Disease: A Single-Center, Randomized, Placebo-Controlled Trial

Biomedicines, 2021
A six-month double-blind, placebo-controlled randomized study was conducted to ascertain whether low-dose daily niacin supplementation would improve motor symptoms in Parkinson’s disease (PD) patients.
Chandramohan Wakade, Raymond Chong, Marissa Seamon, Sharad Purohit, Banabihari Giri, John C. Morgan   +5 more
doaj   +1 more source

Niacin inhibits surface expression of ATP synthase β chain in HepG2 cells: implications for raising HDL

Journal of Lipid Research, 2008
Niacin is an effective agent for raising HDL, but its cellular target sites are largely unknown. We examined effects of niacin on the surface expression of ATP synthase β chain, a newly described HDL/apolipoprotein A-I (apoA-I) receptor for HDL ...
Lin-Hua Zhang, Vaijinath S. Kamanna, Michael C. Zhang, Moti L. Kashyap   +3 more
doaj   +1 more source

Effect of niacin monotherapy on high density lipoprotein composition and function

Lipids in Health and Disease, 2020
Background Niacin has modest but overall favorable effects on plasma lipids by increasing high density lipoprotein cholesterol (HDL-C) and lowering triglycerides.
Scott M. Gordon, Marcelo J. Amar, Kianoush Jeiran, Michael Stagliano, Emma Staller, Martin P. Playford, Nehal N. Mehta, Tomas Vaisar, Alan T. Remaley   +8 more
doaj   +1 more source

Influence of niacin supplementation on the metabolic parameters and lipolysis in dairy cows during early lactation [PDF]

Kafkas Universitesi Veteriner Fakültesi Dergisi, 2017
The objective of this study was to evaluate the effect of niacin on the metabolic parameters and lipolysis inhibition in dairy cows during early lactation.
Talija HRISTOVSKA, Marko CINCOVIĆ, Dragica STOJANOVIĆ, Branislava BELIĆ, Zorana KOVAČEVIĆ, Milanka JEZDIMIROVIĆ   +5 more
doaj   +1 more source

Prolonged niacin treatment leads to increased adipose tissue PUFA synthesis and anti-inflammatory lipid and oxylipin plasma profile[S]

Journal of Lipid Research, 2014
Prolonged niacin treatment elicits beneficial effects on the plasma lipid and lipoprotein profile that is associated with a protective CVD risk profile.
Mattijs M. Heemskerk, Harish K. Dharuri, Sjoerd A.A. van den Berg, Hulda S. Jónasdóttir, Dick-Paul Kloos, Martin Giera, Ko Willems van Dijk, Vanessa van Harmelen   +7 more
doaj   +1 more source

Scientific Opinion on Dietary Reference Values for niacin [PDF]

EFSA Journal, 2014
Following a request from the European Commission, the Panel on Dietetic Products, Nutrition and Allergies (NDA) derived Dietary Reference Values (DRVs) for niacin. Niacin is a generic term for nicotinic acid and nicotinamide. Niacin can be synthesised in
EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA)
doaj   +1 more source

The I148M PNPLA3 variant mitigates niacin beneficial effects: How the genetic screening in non-alcoholic fatty liver disease patients gains value

Frontiers in Nutrition, 2023
BackgroundThe PNPLA3 p.I148M impact on fat accumulation can be modulated by nutrients. Niacin (Vitamin B3) reduced triglycerides synthesis in in vitro and in vivo NAFLD models.ObjectivesIn this study, we aimed to investigate the niacin-I148M polymorphism
Erika Paolini, Erika Paolini, Miriam Longo, Miriam Longo, Marica Meroni, Giada Tria, Annalisa Cespiati, Annalisa Cespiati, Rosa Lombardi, Rosa Lombardi, Sara Badiali, Marco Maggioni, Anna Ludovica Fracanzani, Anna Ludovica Fracanzani, Paola Dongiovanni   +14 more
doaj   +1 more source

Effect of Niacin Precursors on the Excretion of Niacin Metabolites.

Experimental Biology and Medicine, 1950
Conclusions1. The effect of tryptophan, quinolinic acid, ornithine, isocinchomeronic acid, and anthranilic acid on the ability of the rat to form niacin derivatives has been determined.2. Isocinchomeronic acid does not appear to be an intermediate in the synthesis of niacin.3.
L V, HANKES, C A, ELVEHJEM
openaire   +2 more sources

Dietary Mannan‐Rich Fractions Attenuate Weaning Stress in Piglets via Modulating Gut Microbiota and TLR5/NF‐κB Signaling

Animal Research and One Health, EarlyView.
This study aimed to investigate the potential of a mannan‐rich fraction (MRF) as a dietary intervention to alleviate weaning stress in piglets. Our results revealed that MRF could alleviate weaning stress by modulating the gut microbiota and the TLR5/NF‐κB signaling pathway, offering a novel and sustainable alternative to antibiotic use in swine ...
Yutong Lu, Yiwei Sun, Kun Cai, Pingli He, Gang Lin, Zengkai Qi, Hu Liu, Junshu Yan, Ning Ma   +8 more
wiley   +1 more source

Niacin and Stroke: The Role of Supplementation and Emerging Concepts in Clinical Practice, a Narrative Review

Current Issues in Molecular Biology
Niacin therapy has been a mainstay in traditional secondary prevention of stroke. Supplemental use of niacin has been used to improve lipid panel markers, including lowering low-density lipoproteins and triglycerides, and raising high-density ...
Alan D. Kaye, Grant D. Coffman, Sydney A. Mashaw, Austin S. Thomassen, Kalob M. Broocks, Ahmed I. Anwar, Shahab Ahmadzadeh, Sahar Shekoohi   +7 more
doaj   +1 more source