Results 21 to 30 of about 42,137 (194)

Niacin increases HDL biogenesis by enhancing DR4-dependent transcription of ABCA1 and lipidation of apolipoprotein A-I in HepG2 cells

Journal of Lipid Research, 2012
The lipidation of apoA-I in liver greatly influences HDL biogenesis and plasma HDL levels by stabilizing the secreted apoA-I. Niacin is the most effective lipid-regulating agent clinically available to raise HDL.
Lin-Hua Zhang, Vaijinath S. Kamanna, Shobha H. Ganji, Xi-Ming Xiong, Moti L. Kashyap   +4 more
doaj   +1 more source

Effect of niacin monotherapy on high density lipoprotein composition and function

Lipids in Health and Disease, 2020
Background Niacin has modest but overall favorable effects on plasma lipids by increasing high density lipoprotein cholesterol (HDL-C) and lowering triglycerides.
Scott M. Gordon, Marcelo J. Amar, Kianoush Jeiran, Michael Stagliano, Emma Staller, Martin P. Playford, Nehal N. Mehta, Tomas Vaisar, Alan T. Remaley   +8 more
doaj   +1 more source

Association of niacin intake with constipation in adult: result from the National Health and Nutrition Examination

European Journal of Medical Research, 2023
Background Although dietary intake is believed to be associated with constipation, there is currently a lack of research exploring the relationship between niacin intake and constipation. Therefore, the aim of this study is to investigate the association
Xiao Huang, Liwen Zhao, Zhenyang Li, Xiaodong Gu, Mingzhe Li, Jianbin Xiang   +5 more
doaj   +1 more source

Niacin inhibits surface expression of ATP synthase β chain in HepG2 cells: implications for raising HDL

Journal of Lipid Research, 2008
Niacin is an effective agent for raising HDL, but its cellular target sites are largely unknown. We examined effects of niacin on the surface expression of ATP synthase β chain, a newly described HDL/apolipoprotein A-I (apoA-I) receptor for HDL ...
Lin-Hua Zhang, Vaijinath S. Kamanna, Michael C. Zhang, Moti L. Kashyap   +3 more
doaj   +1 more source

Influence of niacin supplementation on the metabolic parameters and lipolysis in dairy cows during early lactation [PDF]

Kafkas Universitesi Veteriner Fakültesi Dergisi, 2017
The objective of this study was to evaluate the effect of niacin on the metabolic parameters and lipolysis inhibition in dairy cows during early lactation.
Talija HRISTOVSKA, Marko CINCOVIĆ, Dragica STOJANOVIĆ, Branislava BELIĆ, Zorana KOVAČEVIĆ, Milanka JEZDIMIROVIĆ   +5 more
doaj   +1 more source

Prolonged niacin treatment leads to increased adipose tissue PUFA synthesis and anti-inflammatory lipid and oxylipin plasma profile[S]

Journal of Lipid Research, 2014
Prolonged niacin treatment elicits beneficial effects on the plasma lipid and lipoprotein profile that is associated with a protective CVD risk profile.
Mattijs M. Heemskerk, Harish K. Dharuri, Sjoerd A.A. van den Berg, Hulda S. Jónasdóttir, Dick-Paul Kloos, Martin Giera, Ko Willems van Dijk, Vanessa van Harmelen   +7 more
doaj   +1 more source

Insufficient or Excessive Niacin Intake Induced Glucose and Lipid Metabolic Disorders and Impaired Liver Health in Nile Tilapia

Aquaculture Nutrition
Niacin (vitamin B3) is involved in the metabolic regulation of energy metabolism in animals. However, both deficiency and excess supplementation of niacin can induce profound physiological disturbances in fish.
Ruixin Li, Jingwen Liu, Jiayong Liang, Lang Liang, Zexuan Kong, Tan Liu, Xiaojuan Liu, Fan Lin, Cuiying Chen, Zhenyu Du, Shuqi Wang   +10 more
doaj   +1 more source

The I148M PNPLA3 variant mitigates niacin beneficial effects: How the genetic screening in non-alcoholic fatty liver disease patients gains value

Frontiers in Nutrition, 2023
BackgroundThe PNPLA3 p.I148M impact on fat accumulation can be modulated by nutrients. Niacin (Vitamin B3) reduced triglycerides synthesis in in vitro and in vivo NAFLD models.ObjectivesIn this study, we aimed to investigate the niacin-I148M polymorphism
Erika Paolini, Erika Paolini, Miriam Longo, Miriam Longo, Marica Meroni, Giada Tria, Annalisa Cespiati, Annalisa Cespiati, Rosa Lombardi, Rosa Lombardi, Sara Badiali, Marco Maggioni, Anna Ludovica Fracanzani, Anna Ludovica Fracanzani, Paola Dongiovanni   +14 more
doaj   +1 more source

Effect of Cyclic Heat Exposure on the Growth Performance and Metabolism of Broilers Fed Palm Kernel Meal

Animal Research and One Health, EarlyView.
The aim of our study is to evaluate the interaction between HS and the incorporation of PKM in broiler chicken diets, as well as its effect on growth performance and metabolism. Based on the results obtained, PKM supplementation failed to mitigate the adverse effects of heat stress in broiler chickens. ABSTRACT The aim of this study was to evaluate the
Ahmed Mijiyawa, Elham Ghashghaei, Okasha Hamada, Huimin Wang, Lijing Sun, Yendouhamtchié Nadiedjoa, Dan Wang, Zhengkai Yue, Clarice Maa Maa Temhoul, Maxwell Ansong Okai, Muhammad Faisal Riaz, Felix Kwame Amevor, Wéré Pitala, Hai Lin   +13 more
wiley   +1 more source

Effects of an Organic Acid Blend on Growth Performance, Redox Homeostasis, and Intestinal Microbiota of Broilers in an Antibiotic‐Free Production System Under Winter Environmental Challenges

Animal Research and One Health, EarlyView.
Schematic summary of the effects of organic acids on growth performance and gut health‐related parameters in broilers. ABSTRACT This study was conducted to evaluate the effects of an organic acid blend on growth performance, redox homeostasis, and intestinal microbiota of broilers raised in an antibiotic‐free system during the winter season in China ...
Rong‐Hui Huang, Hong‐Lin Li, Yu Zhang, Jie Wang, Shao‐Qing Wang, Xue‐Wu Li, Lane Pineda, Xiang‐Dong Kuang, Giseli Heim, Mahmoud Mohamed Khalil, Lv‐Hui Sun, Zhang‐Chao Deng   +11 more
wiley   +1 more source