Results 41 to 50 of about 34,921 (207)
BackgroundEnd-stage kidney disease (ESRD) patients on dialysis face pronounced cardiovascular and metabolic risks due to disruptions in lipoprotein(a), phosphorus, potassium, uric acid, and lipid balance.
Amira Reda Muhammad Galal +8 more
doaj +1 more source
Background Chronic kidney disease (CKD), which has become a global public health issue, is associated with mitochondrial dysfunction. Niacin is a necessary coenzyme for mitochondrial energy metabolism.
Qishu Li, Wei Lan
doaj +1 more source
Pharmacological doses of niacin can improve lipid metabolism in humans and some homothermal model organisms, but flushing and hepatotoxicity are the main side-effects.
Wei Liu +6 more
doaj +1 more source
Niacin as a drug repositioning candidate for hyperphosphatemia management in dialysis patients
Sooyoung Shin, Sukhyang LeeAjou University College of Pharmacy, Yeongtong-gu, Suwon-si, Gyeonggi-do, Korea Abstract: Nearly all patients with end-stage renal disease develop hyperphosphatemia.
Shin S, Lee S
doaj
Abstract The dietary and lifestyle practices have predominantly compromised human health, which are influenced by modernization and industrialization. Hypercholesterolemia, caused by the consumption of fatty and fried foods and a sedentary lifestyle, is a major modifiable risk factor for cardiovascular disease and commonly coexists with obesity ...
Muhammad Usman Khalid +8 more
wiley +1 more source
Macronutrient and micronutrient profiles of meat types: insights into human health and diet
Abstract Despite considerable advances in global health and nutrition, emerging challenges such as population growth, climate change, and limited natural resources continue to threaten food security. Meat remains an essential component of the human diet, supplying high‐quality proteins, essential amino acids, lipids, vitamins, and minerals necessary ...
Özgül Anitaş +4 more
wiley +1 more source
Bee pollen as functional food and environmental bioindicator: current evidence and future challenges
Abstract Bee pollen (BP), a plant‐derived product collected by honey bees, is increasingly promoted as a functional food due to its content of proteins, essential amino acids, lipids, vitamins, minerals, and bioactive compounds such as polyphenols and flavonoids.
Luigi Parrotta, Stefano Del Duca
wiley +1 more source
Dietary NA restriction converts the effect of NAMPT inhibition from cytostatic to cytotoxic in SCLC in vivo. ABSTRACT Small‐cell lung cancer (SCLC) is an aggressive malignancy with limited therapeutic options. We previously showed that nicotinic acid riboside (NAR) sustains NAD biosynthesis in vivo and compensates for NAMPT inhibition in SCLC models ...
Kyoji Tsurumi +12 more
wiley +1 more source
Niacin Deficiency in Rabbits and Response to Tryptophane and to Niacin
SummaryIn the study reported above, it is shown that the exclusion of niacin from the ration of rabbits for 8 weeks was accompanied by a reduction of hemoglobin and the cellular components of the blood. After 12 weeks on this ration, there was a reduction of niacin concentration in the livers and the hamstring muscles.After the animals had been on the ...
openaire +2 more sources
SUMMARY Prurigo pigmentosa (PP) is a rare inflammatory dermatosis, clinically characterized by intensely pruritic, erythematous papules and papulovesicles, with reticular hyperpigmentation upon healing. We herein report four cases in adults of different ethnic backgrounds, in which the disease was associated with ketogenic metabolic states due to ...
Antigona Aliu +7 more
wiley +1 more source

