Results 31 to 40 of about 75,252 (228)
Biomedicines, 2021 A six-month double-blind, placebo-controlled randomized study was conducted to ascertain whether low-dose daily niacin supplementation would improve motor symptoms in Parkinson’s disease (PD) patients.
Chandramohan Wakade +5 more
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Pharmacological doses of niacin stimulate the expression of genes involved in carnitine uptake and biosynthesis and improve the carnitine status of obese Zucker rats [PDF]
, 2014 BACKGROUND: Activation of peroxisome proliferator-activated receptor (PPAR)alpha and PPARdelta causes an elevation of tissue carnitine concentrations through induction of genes involved in carnitine uptake [novel organic cation transporter 2, (OCTN2 ...
Couturier, Aline +3 more
core +2 more sources
European Journal of Medical Research, 2023 Background Although dietary intake is believed to be associated with constipation, there is currently a lack of research exploring the relationship between niacin intake and constipation. Therefore, the aim of this study is to investigate the association
Xiao Huang +5 more
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Niacin supplementation increases the number of oxidative type I fibers in skeletal muscle of growing pigs [PDF]
, 2013 Background: A recent study showed that niacin supplementation counteracts the obesity-induced muscle fiber switching from oxidative type I to glycolytic type II and increases the number of type I fibers in skeletal muscle of obese Zucker rats.
Eder, Klaus +5 more
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Kidney Research and Clinical Practice, 2013 Background: Niacin supplementation improves dyslipidemia and lowers serum phosphorus levels in patients with chronic kidney disease (CKD). We evaluated whether low-dose niacin supplementation can improve dyslipidemia, lower serum phosphorus levels, and ...
Hyo Jin Kang +8 more
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G protein-coupled receptors not currently in the spotlight: free fatty acid receptor 2 and GPR35 [PDF]
, 2017 It is widely appreciated that G protein-coupled receptors have been the most successfully exploited class of targets for the development of small molecule medicines. Despite this, to date, less than 15% of the non-olfactory G protein-coupled receptors in
Milligan, Graeme
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Journal of Lipid Research, 2008 Niacin is an effective agent for raising HDL, but its cellular target sites are largely unknown. We examined effects of niacin on the surface expression of ATP synthase β chain, a newly described HDL/apolipoprotein A-I (apoA-I) receptor for HDL ...
Lin-Hua Zhang +3 more
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Journal of Lipid Research, 2014 Prolonged niacin treatment elicits beneficial effects on the plasma lipid and lipoprotein profile that is associated with a protective CVD risk profile.
Mattijs M. Heemskerk +7 more
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Effect of niacin monotherapy on high density lipoprotein composition and function
Lipids in Health and Disease, 2020 Background Niacin has modest but overall favorable effects on plasma lipids by increasing high density lipoprotein cholesterol (HDL-C) and lowering triglycerides.
Scott M. Gordon +8 more
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Scientific Opinion on Dietary Reference Values for niacin [PDF]
EFSA Journal, 2014 Following a request from the European Commission, the Panel on Dietetic Products, Nutrition and Allergies (NDA) derived Dietary Reference Values (DRVs) for niacin. Niacin is a generic term for nicotinic acid and nicotinamide. Niacin can be synthesised in
EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA)
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