Results 11 to 20 of about 33,672 (206)

Insufficient or Excessive Niacin Intake Induced Glucose and Lipid Metabolic Disorders and Impaired Liver Health in Nile Tilapia [PDF]

Aquaculture Nutrition
Niacin (vitamin B3) is involved in the metabolic regulation of energy metabolism in animals. However, both deficiency and excess supplementation of niacin can induce profound physiological disturbances in fish.
Ruixin Li, Jingwen Liu, Jiayong Liang, Lang Liang, Zexuan Kong, Tan Liu, Xiaojuan Liu, Fan Lin, Cuiying Chen, Zhenyu Du, Shuqi Wang   +10 more
doaj   +2 more sources

Targeting cardiovascular and metabolic risk modification in end stage renal disease (ESRD): a randomized controlled clinical trial on niacin’s effects on lipoprotein(a) and biochemical markers in hemodialysis patients [PDF]

Frontiers in Medicine
BackgroundEnd-stage kidney disease (ESRD) patients on dialysis face pronounced cardiovascular and metabolic risks due to disruptions in lipoprotein(a), phosphorus, potassium, uric acid, and lipid balance.
Amira Reda Muhammad Galal, Maha Abdel Rhman Salah, Ammena Y. Binsaleh, Nawal Alsubaie, Amani S. Alrossies, Ahmed Hassan Elthakaby, Ghadir Mohamed Elsawy, Azza A. Ali, Zeinab Al Kasaby Zalat   +8 more
doaj   +2 more sources

Niacin ameliorates ulcerative colitis via prostaglandin D 2 ‐mediated D prostanoid receptor 1 activation

EMBO Molecular Medicine, 2017
Niacin, as an antidyslipidemic drug, elicits a strong flushing response by release of prostaglandin (PG) D2. However, whether niacin is beneficial for inflammatory bowel disease (IBD) remains unclear. Here, we observed niacin administration‐enhanced PGD2
Deping Kong, Yanping Tang, Tingting Bai   +2 more
exaly   +2 more sources

Niacin [PDF]

Advances in Nutrition, 2016
Nicotinic acid and nicotinamide, collectively referred to as niacin, are nutritional precursors of the bioactive molecules nicotinamide adenine dinucleotide (NAD) and nicotinamide adenine dinucleotide phosphate (NADP). NAD and NADP are important cofactors for most cellular redox reactions, and as such are essential to maintain cellular metabolism and ...
James B, Kirkland, Mirella L, Meyer-Ficca   +1 more
  +8 more sources

Niacin inhibits vascular calcification via modulating of SIRT1/SIRT6 signaling pathway [PDF]

Cell Death Discovery
Vascular calcification (VC) is a common pathological state that often accompanies calcium-phosphorus metabolism disorder and chronic kidney diseases (CKDs).
Chao-hua Kong, Li-da Wu, Yue Sun, Xiao-min Jiang, Yi Shi, Feng Wang, Dong-chen Wang, Yue Gu, Wen-ying Zhou, Jin-que Luo, Shao-liang Chen, Yue-lin Chao   +11 more
doaj   +2 more sources

Niacin enhances hematoma clearance and neurological recovery via the HCAR2/SIRT1/Nrf2 pathway after germinal matrix hemorrhage [PDF]

Redox Biology
Germinal matrix hemorrhage (GMH) is a common form of neonatal stroke in preterm infants and often results in severe and lasting neurological deficits. Persistent hematoma is a key contributor to secondary brain injury.
Xiong Liu, Cheng Cao, Ningbo Xu, Feng Xu, Lei Huang, Prativa Sherchan, Desislava Met Doycheva, John H. Zhang, Jiping Tang, Jerry J. Flores, Xionghui Chen   +10 more
doaj   +2 more sources

Niacin exacerbates β cell lipotoxicity in diet-induced obesity mice through upregulation of GPR109A and PPARγ2: Inhibition by incretin drugs

Frontiers in Endocrinology, 2022
The widely used lipid-lowering drug niacin was reported to increase blood glucose in diabetes. How does niacin regulate β Cell function in diabetic patients remains unclear.
Xiaojing Zhang, Baoyi Zhu, Peibin Lin, Xiaoping Liu, Jun Gao, Dazhong Yin, Jianwen Zeng, Baojian Liao, Baojian Liao, Zhanfang Kang   +9 more
doaj   +1 more source

Niacin Status Indicators and Their Relationship with Metabolic Parameters in Dairy Cows during Early Lactation

Animals, 2022
Previous experimental models on cows have examined the difference in the metabolic adaptation in cows after niacin administration, without identifying the most important mediators between niacin administration and its biological effects, namely active ...
Kosta Petrović, Radojica Djoković, Marko Cincović, Talija Hristovska, Miroslav Lalović, Miloš Petrović, Mira Majkić, Maja Došenović Marinković, Ljiljana Anđušić, Gordana Devečerski, Dragica Stojanović, Filip Štrbac   +11 more
doaj   +1 more source

The interaction of dietary niacin and lipid affects the growth, antioxidant capacity and lipid metabolism of male Eriocheir sinensis

Aquaculture Reports, 2023
A 60-day feeding trial was conducted to determine the effects of the interaction of dietary niacin and lipid on the growth, antioxidant capacity and lipid metabolism in male Eriocheir sinensis.
Wenlong Wan, Jie Xu, Jiayuan Shi, Xin Zhang, Anran Wang, Xiaojing Dong, Shuyan Miao   +6 more
doaj   +1 more source

Niacin – a scoping review for Nordic Nutrition Recommendations 2023

Food & Nutrition Research, 2023
Niacin is the precursor to pyridine nucleotides NAD (nicotinamide adenine dinucleotide) and NADP (nicotinamide adenine dinucleotide phosphate). Niacin (vitamin B3) is the common term for nicotinic acid, nicotinamide and derivatives that exhibit the ...
Riitta Freese, Vegard Lysne
doaj   +1 more source