Results 51 to 60 of about 91,799 (300)

Niacin supplementation increases the number of oxidative type I fibers in skeletal muscle of growing pigs [PDF]

, 2013
Background: A recent study showed that niacin supplementation counteracts the obesity-induced muscle fiber switching from oxidative type I to glycolytic type II and increases the number of type I fibers in skeletal muscle of obese Zucker rats.
Eder, Klaus, Khan, Muckta, Krüger, Karsten, Mooren, Frank-Christoph, Most, Erika, Ringseis, Robert   +5 more
core   +2 more sources

Niacin-mediated rejuvenation of macrophage/microglia enhances remyelination of the aging central nervous system

Acta Neuropathologica, 2020
Remyelination following CNS demyelination restores rapid signal propagation and protects axons; however, its efficiency declines with increasing age. Both intrinsic changes in the oligodendrocyte progenitor cell population and extrinsic factors in the ...
Khalil S. Rawji, Adam M. H. Young, Tanay Ghosh, Nathan J. Michaels, R. Mirzaei, J. Kappen, Kathleen L. Kolehmainen, Nima Alaeiilkhchi, Brian M. Lozinski, M. Mishra, Annie Pu, Weiwen Tang, S. Zein, D. K. Kaushik, M.B. Keough, Jason R. Plemel, Fiona Calvert, Andrew J. Knights, Daniel J. Gaffney, W. Tetzlaff, R. Franklin, V. W. Yong   +21 more
semanticscholar   +1 more source

Niacin Increases Atherogenic Proteins in High-Density Lipoprotein of Statin-Treated Subjects

Arteriosclerosis, Thrombosis and Vascular Biology, 2021
Supplemental Digital Content is available in the text. Objective: Niacin therapy fails to reduce cardiovascular events in statin-treated subjects even though it increases plasma HDL-C (HDL [high-density lipoprotein] cholesterol) and decreases LDL-C (LDL [
G. Ronsein, T. Vaisar, W. Davidson, K. Bornfeldt, J. Probstfield, K. O’Brien, X. Zhao, J. Heinecke   +7 more
semanticscholar   +1 more source

Network Pharmacology and bioinformatics analyses identify intersection genes of niacin and COVID-19 as potential therapeutic targets

Briefings Bioinform., 2020
Objectives Patients with colorectal cancer (CRC) may be susceptible to the coronavirus disease-2019 (COVID-19). However, anti-CRC/COVID-19 treatment options are currently unavailable.
Rong-chun Li, Yu Li, X. Liang, Lu Yang, M. Su, K. Lai   +5 more
semanticscholar   +1 more source

Niacin increases HDL biogenesis by enhancing DR4-dependent transcription of ABCA1 and lipidation of apolipoprotein A-I in HepG2 cells

Journal of Lipid Research, 2012
The lipidation of apoA-I in liver greatly influences HDL biogenesis and plasma HDL levels by stabilizing the secreted apoA-I. Niacin is the most effective lipid-regulating agent clinically available to raise HDL.
Lin-Hua Zhang, Vaijinath S. Kamanna, Shobha H. Ganji, Xi-Ming Xiong, Moti L. Kashyap   +4 more
doaj   +1 more source

Influence of niacin supplementation on the metabolic parameters and lipolysis in dairy cows during early lactation [PDF]

Kafkas Universitesi Veteriner Fakültesi Dergisi, 2017
The objective of this study was to evaluate the effect of niacin on the metabolic parameters and lipolysis inhibition in dairy cows during early lactation.
Talija HRISTOVSKA, Marko CINCOVIĆ, Dragica STOJANOVIĆ, Branislava BELIĆ, Zorana KOVAČEVIĆ, Milanka JEZDIMIROVIĆ   +5 more
doaj   +1 more source

Effects of niacin restriction on sirtuin and PARP responses to photodamage in human skin. [PDF]

, 2012
Sirtuins (SIRTs) and poly(ADP-ribose) polymerases (PARPs), NAD(+)-dependent enzymes, link cellular energy status with responses to environmental stresses.
Benavente, Claudia A, Jacobson, Elaine L, Schnell, Stephanie A   +2 more
core   +9 more sources

Physicians' Experiences as Patients with Statin Side Effects: A Case Series. [PDF]

, 2017
Physicians are among those prescribed statins and therefore, subject to potential statin adverse effects (AEs). There is little information on the impact of statin AEs on physicians affected by them. We sought to assess the character and impact of statin
Golomb, Beatrice Alexandra, Koslik, Hayley J, Meskimen, Athena Hathaway   +2 more
core   +2 more sources

Effects of low-dose niacin on dyslipidemia and serum phosphorus in patients with chronic kidney disease

Kidney Research and Clinical Practice, 2013
Background: Niacin supplementation improves dyslipidemia and lowers serum phosphorus levels in patients with chronic kidney disease (CKD). We evaluated whether low-dose niacin supplementation can improve dyslipidemia, lower serum phosphorus levels, and ...
Hyo Jin Kang, Do Kyong Kim, Su Mi Lee, Kyung Han Kim, Seung Hee Han, Ki Hyun Kim, Seong Eun Kim, Young Ki Son, Won Suk An   +8 more
doaj   +1 more source

Dietary Niacin Intake and Mortality Among Individuals With Nonalcoholic Fatty Liver Disease

JAMA Network Open
Key Points Question Is higher dietary niacin intake associated with lower risk of all-cause mortality and cardiovascular disease mortality among individuals with nonalcoholic fatty liver disease (NAFLD)?
Jie Pan, Yujia Zhou, Nengzhi Pang, Lili Yang   +3 more
semanticscholar   +1 more source