Results 41 to 50 of about 927,461 (351)
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
NeuroImage: Clinical, 2016 Background: The main focus of studies of individuals at ultra-high risk for psychosis (UHR) has been on identifying brain changes in those individuals who will develop psychosis. However, longitudinal studies have shown that up to half of UHR individuals
Sanne de Wit, MSc +7 more
doaj +1 more source
Isotopic niche variability in macroconsumers of the East Scotia Ridge (Southern Ocean) hydrothermal vents: What more can we learn from an ellipse? [PDF]
, 2016 Aspects of between-individual trophic niche width can be explored through the isotopic niche concept. In many cases isotopic variability can be influenced by the scale of sampling and biological characteristics including body size or sex.
McGill, R.A.R. +4 more
core +2 more sources
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
FEBS Letters, EarlyView.The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
Resistin Regulates Inflammation and Insulin Resistance in Humans via the Endocannabinoid System
ResearchResistin plays an important role in the pathophysiology of obesity-mediated insulin resistance in mice. However, the biology of resistin in humans is quite different from that in rodents. Therefore, the association between resistin and insulin resistance
Han-Mo Yang +11 more
doaj +1 more source
Quantitative microscopy of the Drosophila ovary shows multiple niche signals specify progenitor cell fate. [PDF]
, 2017 Adult stem cells commonly give rise to transit-amplifying progenitors, whose progeny differentiate into distinct cell types. It is unclear if stem cell niche signals coordinate fate decisions within the progenitor pool.
Burrous, Haley +4 more
core +2 more sources
Hematopoietic (stem) cells—The elixir of life?
FEBS Letters, EarlyView.The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo +4 more
wiley +1 more source
Investigation of the heterogeneity of cancer cells using single cell Ca2+ profiling
Cell Communication and SignalingBackground Calcium (Ca2+) is an essential second messenger that controls numerous cellular functions. Characteristics of intracellular Ca2+ oscillations define Ca2+ signatures representatives of the phenotype of a cell.
Amélie E. Bura +11 more
doaj +1 more source
Engineering of Eu dopant segregation in colquiriite-type fluoride single crystal scintillators
AIP Advances, 2017 Colquiriite-type Eu-doped LiCaAlF6 and LiSrAlF6 (Eu:LiCAF and Eu:LiSAF) scintillator single crystals were grown using Al metal as a starting material to improve the Eu dopant segregation.
Yuui Yokota +5 more
doaj +1 more source
Competência, 2016 O presente artigo apresenta uma síntese teórico-epistemológica resultante do constructo metodológico adotado no processo investigativo que contemplou discursos de docentes e discentes sobre práticas pedagógicas no âmbito da ...
Augusto Niche Teixeira +1 more
doaj +1 more source