Reversing Antibiotic Resistance: Strategies From Adjuvants to Innovative Therapeutics
MicrobiologyOpen, Volume 15, Issue 1, February 2026.Molecular reversal strategies against antibiotic resistance act through three mechanisms: inhibiting resistance gene function, blocking horizontal gene transfer, and modulating host defense. Emerging technologies, such as CRISPR‐Cas gene editing, photodynamic therapy, nanotechnology, and ecological competition, further strengthen these approaches ...
Tianjiao Li +4 more
wiley +1 more source
Parasites & Vectors, 2022 Background Snail intermediate hosts are mandatory for the transmission of schistosomiasis, which has to date infected more than 200 million people worldwide.
Ni Jiang +7 more
doaj +1 more source
Aquaporin modulators: a patent review (2010-2015) [PDF]
, 2016 Introduction: Since the discovery of aquaporin-1 (AQP1) as a water channel, more than 2,000 articles, reviews and chapters have been published.
Casini, Angela, Soveral, Graça
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Strategic Preparedness of Broad‐Spectrum Antivirals for Rapid Response Towards Next Pandemics
Small Science, Volume 6, Issue 1, January 2026.Nanoengineered broad‐spectrum antivirals (BSAs) represent a transformative approach to pandemic preparedness. Unlike virus‐specific drugs requiring separate development, BSAs act across multiple viral families through nanoengineering strategies that enhance solubility, bioavailability, and host‐targeted activity.
Sanoj Rejinold N +2 more
wiley +1 more source
Niclosamide and its derivative DK‐520 inhibit RANKL‐induced osteoclastogenesis
FEBS Open Bio, 2020 Niclosamide is a potent inhibitor of osteoclastogenesis and bone remodeling. DK‐520 is an acyl derivative of Niclosamide and significantly increased both the plasma concentration and the duration of exposure of Niclosamide when dosed orally.
Yurui Jiao +7 more
doaj +1 more source
Low Transmission to Elimination: Rural Development as a Key Determinant of the End-Game Dynamics of Schistosoma japonicum in China. [PDF]
, 2017 Rural development has been a critical component of China's economic miracle since the start of economic reform in the early 1980s, both benefiting from and contributing to the nation's rapid economic growth.
Liang, Song, Spear, Robert, Zhong, Bo
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Voltammetric Determination of Niclosamide
, 1991 Department of Chemistry, S. V. U. College of Engineering, Tirupati-517 502 Manuscript received 9 February 1990, revised 7 January 1991, accepted 8 May 1991 The electrochemical behaviour of niclosamide is described on the basis of the study carried out using d.c. polarography, cyclic voltammetry, a.c.
C. SRIDEVI, S. JAYARAMA REDDY
openaire +1 more source
Perceptions and acceptability of piloted Taenia solium control and elimination interventions in two endemic communities in eastern Zambia [PDF]
, 2020 Infections with Taenia solium cause significant public health and economic losses worldwide. Despite effective control tools, long‐term sustained control/elimination of the parasite has not been demonstrated to date.
Chembensofu, Mwelwa +15 more
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Colistin Resistance in Bacteria: Current Updates on Mechanism of Action and Combating Strategies
Canadian Journal of Infectious Diseases and Medical Microbiology, Volume 2026, Issue 1, 2026.The rapid development of colistin‐resistant bacteria is the biggest global health issue since colistin is referred to as a ‘last‐hope resource’ against life‐threatening infections caused by GNB (Gram‐negative bacteria). Injudicious and excessive colistin application in clinical, agricultural and veterinary practices, as well as plasmid‐mediated ...
Indu Singh +5 more
wiley +1 more source
Identification of Pharmacological Modulators of HMGB1-Induced Inflammatory Response by Cell-Based Screening [PDF]
, 2013 High mobility group box 1 (HMGB1), a highly conserved, ubiquitous protein, is released into the circulation during sterile inflammation (e.g. arthritis, trauma) and circulatory shock.
A Lahat +40 more
core +4 more sources