Results 141 to 150 of about 132,023 (311)

Synthesis of Bispecific Conjugates by ADP‐Ribosyl Cyclases

Advanced Science, EarlyView.
Genetic fusion of a CD38 enzymatic domain to antibody scaffolds allows site‐specific conjugation of small‐molecule ligands. Using this approach, a PSMA ligand DUPA is conjugated with an anti‐human CD3 Fab antibody. The resulting bispecific anti‐CD3‐DUPA conjugate facilitates recruitment and activation of cytotoxic T cells against PSMA‐expressing ...
Sunny H. Kim, Arshad J. Ansari, Lei Zhang, Guoyun Kao, Thuc Oanh Hoang, Zeyu Zhang, Srinivasarao Singireddi, Benjamin B. Katz, Yong Zhang   +8 more
wiley   +1 more source

The inhibition of pig kidney alkaline phosphatase by oxidized or reduced nicotinamide–adenine dinucleotide and related compounds [PDF]

, 1973
Indra Ramasamy, Peter Butterworth
openalex   +1 more source

NUDT21‐mediated Alternative Polyadenylation of CDK19 Reprograms Cholesterol Biosynthesis to Drive Colorectal Cancer Progression

Advanced Science, EarlyView.
NUDT21 is overexpressed in colorectal cancer tumors and promotes colorectal cancer progression. NUDT21 promotes the production of a cyclin‐dependent kinase 19 (CDK19) mRNA isoform with a long 3′ UTR, which enhances cytoplasmic export and translation. Truncation of the CDK19 long 3′ UTR phenocopies NUDT21 loss, recapitulating the defects in cholesterol ...
Yeping Yu, Jixin Ma, Minwei Zhou, Xiaodong Gu, Yiming Zhou, Zhenyang Li, Tianyu Zhang, Wei Gong, Chuanxin Huang, Jianbin Xiang   +9 more
wiley   +1 more source

Nicotinamide riboside enhances liver regeneration via the MCART1/ASB3 axis in obesity-compromised rats. [PDF]

Hepatol Commun
Wang H, Li H, Liu Y, Wang X, He C, Huang J, Zhang Y, Yang Y, Ge N.   +8 more
europepmc   +1 more source

The Vitamin B Complex and Fasting Blood-Sugar Levels: An Investigation into the Changes in Fasting Blood-Sugar Levels of Diabetic and Non-diabetic Patients Following the Intravenous Injection of Aneurin, Riboflavin and Nicotinamide, with a Review of Relevant Literature, and a Note on Diabetic Neuritis [PDF]

, 1949
Charles M. Wylie
openalex  

Discovery of DS68702229 as a Potent, Orally Available NAMPT (Nicotinamide Phosphoribosyltransferase) Activator

, 2021
Mayuko Akiu, Takashi Tsuji, Kouki Iida, Yoshitaka Sogawa, Koji Terayama, Mika Yokoyama, Jun Tanaka, Daigo Asano, Tomohiro Honda, Ken Sakurai, Anthony B. Pinkerton, Tsuyoshi Nakamura   +11 more
openalex   +2 more sources

Chaperone‐Mediated Autophagic Degradation of USP9X in Macrophages Exacerbates Postmyocardial Infarction Inflammation and Cardiac Dysfunction

Advanced Science, EarlyView.
This study demonstrates that inflammatory stimuli induce the acetylation‐triggered, chaperone‐mediated autophagic degradation of ubiquitin‐specific peptidase 9 X‐linked (USP9X) in macrophages. USP9X acts as a macrophage “inflammation switch” after myocardial infarction (MI). USP9X loss destabilizes tumor necrosis factor receptor‐associated factor (TRAF)
Biqing Wang, Xiangheng Cai, Mengqi Li, Xue Liu, Junhui Xue, Ye Liu, Ding Ai, Xinyang Hu   +7 more
wiley   +1 more source

Correlation between concentrations of NAMPT and NMNAT1 and the risk of upper respiratory infections in the island reef. [PDF]

World J Clin Cases
Gao GF, Yu J, Liu SY.
europepmc   +1 more source

Nanozymes Integrated Biochips Toward Smart Detection System

Advanced Science, EarlyView.
This review systematically outlines the integration of nanozymes, biochips, and artificial intelligence (AI) for intelligent biosensing. It details how their convergence enhances signal amplification, enables portable detection, and improves data interpretation.
Dongyu Chen, Wang Zheng, Zhihui Zhang, Shenping Yu, Xinxin Hang, Han Wu, Xiao‐Wei Xiang, Wei Mu, Yanli Jiao, Zaizai Dong, Lingqian Chang   +10 more
wiley   +1 more source

Assessment of the feed additives menadione sodium bisulphite (3a710) and menadione nicotinamide bisulphite (3a711) (vitamin K₃) for all animal species for the renewal of their authorisation (DSM Nutritional Products Ltd, KH Boddin GmbH, Oxyvit Kimya San. Ve Tic. A.Ş., Orffa Additives BV, FNF Ingredients EU BV, ADM International SàRL). [PDF]

EFSA J
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP), Villa RE, Azimonti G, Bonos E, Christensen H, Durjava M, Dusemund B, Gehring R, Glandorf B, Kouba M, López-Alonso M, Marcon F, Nebbia C, Pechová A, Prieto-Maradona M, Röhe I, Theodoridou K, Ørnsrud R, Galobart J, Manini P, Navarro-Villa A, Pizzo F, Vettori MV, Gkimprixi E.   +23 more
europepmc   +1 more source