Results 21 to 30 of about 125,589 (257)

Topical nicotinamide in combination with calcipotriol for the treatment of mild to moderate psoriasis: A double-blind, randomized, comparative study

Advanced Biomedical Research, 2013
Background: Current treatment strategies of psoriasis are not completely satisfactorily. By inhibiting inflammatory cytokines, nicotinamide may enhance the effects of current topical treatments.
Amir Hossein Siadat, Fariba Iraji, Mehdi Khodadadi, Maryam Kalateh Jary   +3 more
doaj   +1 more source

Dissolution Enhancement of Atorvastatin Calcium by Cocrystallization [PDF]

Advanced Pharmaceutical Bulletin, 2019
Purpose: To enhance the dissolution rate of the poorly soluble drug atorvastatin calcium (ATC) by cocrystallization with selected coformers. Enhancement of the dissolution rate and solubility of the drug, which is classified as Class II of the ...
Reham Al-Kazemi, Yacoub Al-Basarah, Aly Nada   +2 more
doaj   +1 more source

Nicotinamide Content of Insects [PDF]

Australian Journal of Biological Sciences, 1965
Surprisingly little is known of the vitamin content of insects and consequently, as part of an investigation of the function and metabolism of insect tissues, we have determined the nicotinamide content of a wide range of adult insects collected locally in the Wellington district.
G B, Kitto, M H, Briggs
openaire   +2 more sources

Diosmin Potentiates the Antidiabetic Effects of Linagliptin in Nicotinamide/Streptozotocin-Induced Diabetic Wistar Rats

Pharmaceuticals
Background/Objectives: Natural therapeutics for the treatment of diabetes mellitus represent a common challenge for many researchers. Thus, the aim of this study was to evaluate the antihyperglycemic and anti-inflammatory effects and the hepatic ...
Eman B. Abbas, Asmaa M. El-Kalaawy, Noha A. Ahmed, Anwar Shams, Amal K. Khaliefa, Osama M. Ahmed   +5 more
doaj   +1 more source

RETRACTED: Nicotinamide Ameliorates Amyloid Beta-Induced Oxidative Stress-Mediated Neuroinflammation and Neurodegeneration in Adult Mouse Brain

Biomedicines, 2021
Alzheimer’s disease (AD) is the most predominant age-related neurodegenerative disease, pathologically characterized by the accumulation of aggregates of amyloid beta Aβ1–42 and tau hyperphosphorylation in the brain.
Inayat Ur Rehman, Riaz Ahmad, Ibrahim Khan, Hyeon Jin Lee, Jungsung Park, Rahat Ullah, Myeong Jun Choi, Hee Young Kang, Myeong Ok Kim   +8 more
doaj   +1 more source

Nicotinamide: A cardioprotective form of Vitamin B3 [PDF]

Arhiv za farmaciju
Nicotinamide, a form of vitamin B3, has emerged as a potential cardioprotective agent against ischemia-reperfusion (I/R) injury, a critical factor in the pathogenesis of myocardial infarction, heart failure, and other cardiovascular diseases.
Du Qingyou
doaj   +1 more source

Design, Synthesis, In Silico and In Vitro Studies of New Immunomodulatory Anticancer Nicotinamide Derivatives Targeting VEGFR-2

Molecules, 2022
VEGFR-2, the subtype receptor tyrosine kinase (RTK) responsible for angiogenesis, is expressed in various cancer cells. Thus, VEGFER-2 inhibition is an efficient approach for the discovery of new anticancer agents.
Reda G. Yousef, Wagdy M. Eldehna, Alaa Elwan, Abdelaziz S. Abdelaziz, Ahmed B. M. Mehany, Ibraheem M. M. Gobaara, Bshra A. Alsfouk, Eslam B. Elkaeed, Ahmed M. Metwaly, Ibrahim H. Eissa   +9 more
doaj   +1 more source

Synthesis and structure of diaquabis(nicotinamide-κO)bis(nitrato-κ2O,O′)calcium(II)

Acta Crystallographica Section E: Crystallographic Communications
The title complex, [Ca(NO3)2(C6H6N2O)2(H2O)2], crystallizes with an eight-coordinate Ca2+ ion in a distorted trigonal–dodecahedral coordination environment.
Zulfiya Djumanazarova, Shakhnoza Kadirova, Nuritdin Kattaev, Bakhtiyar Ibragimov, Saule Meldebekova, Jamshid Ashurov   +5 more
doaj   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Nicotinamide and Pyridoxine in Muscle Aging: Nutritional Regulation of Redox, Inflammation, and Regeneration

Antioxidants
Sarcopenia, the progressive loss of muscle mass, strength, and regenerative capacity with age, is driven by interconnected processes such as oxidative stress, chronic inflammation, mitochondrial dysfunction, and reduced activity of muscle stem cells.
Agnieszka Nowacka, Maciej Śniegocki, Martyna Śniegocka, Ewa A. Ziółkowska   +3 more
doaj   +1 more source