Results 41 to 50 of about 159,186 (304)

NICOTINAMIDE IN COMPLEX TREATMENT OF LARGE-PLAQUE PARAPSORIASIS AND EARLY STAGES OF MALIGNANT T-CELL SKIN LYMPHOMAS

Alʹmanah Kliničeskoj Mediciny, 2016
Aim: To assess clinical efficacy of nicotinamide in 2 the treatment of patients with early stages of malignant T-cell skin lymphomas and large-plaque parapsoriasis.
I. V. Khamaganova, O. N. Pomerantsev, O. L. Novozhilova, V. P. Mitroshina, O. I. Shvets   +4 more
doaj   +1 more source

Nicotinamide Supplementation Improves Oocyte Quality and Offspring Development by Modulating Mitochondrial Function in an Aged Caenorhabditis elegans Model

Antioxidants, 2021
Aging is associated with a decline in the quality of biological functions. Among the aging processes, reproductive aging is a critical process because of its intergenerational effects.
Hyemin Min, Mijin Lee, Kyoung Sang Cho, Hyunjung Jade Lim, Yhong-Hee Shim   +4 more
doaj   +1 more source

Re‐Purposing Sapropterin (Kuvan) for ACTA2‐Related Multisystemic Smooth Muscle Dysfunction Syndrome: A Translational Mechanistic and First‐In‐Human Therapeutic Report

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem, Noa Bielopolski, Vijai Krishnan, Shane Wald‐Altman, Shelly I Shrian, Omer Bar‐Yosef, Livia Kapusta, Claire Shamber, Patricia L. Musolino, Miguel Weil   +9 more
wiley   +1 more source

N,1-Bis(4-ethoxyphenyl)-2,6-dimethyl-4-oxo-1,4-dihydropyridine-3-carboxamide

IUCrData, 2018
Condensation of ethyl acetoacetate and phenetidine gives the title compound, C24H26N2O4. The planar ethoxyphenyl group attached to the pyridine ring is twisted about 77.96 (11)° out of the plane of the N-ethoxycarboxamidopyridine unit.
Heiner Detert, Peter Bachon, Dieter Schollmeyer   +2 more
doaj   +1 more source

NADomics: Measuring NAD⁺ and Related Metabolites Using Liquid Chromatography Mass Spectrometry

Life, 2021
Nicotinamide adenine dinucleotide (NAD+) and its metabolome (NADome) play important roles in preserving cellular homeostasis. Altered levels of the NADome may represent a likely indicator of poor metabolic function.
Nady Braidy, Maria D. Villalva, Ross Grant   +2 more
doaj   +1 more source

Nicotinamide Content of Insects [PDF]

Australian Journal of Biological Sciences, 1965
Surprisingly little is known of the vitamin content of insects and consequently, as part of an investigation of the function and metabolism of insect tissues, we have determined the nicotinamide content of a wide range of adult insects collected locally in the Wellington district.
G B, Kitto, M H, Briggs
openaire   +2 more sources

NNMT (nicotinamide N-methyltransferase) [PDF]

, 2010
Review on NNMT (nicotinamide N-methyltransferase), with data on DNA, on the protein encoded, and where the gene is ...
Pozzi, V, D Sartini, Cecati, M, EMANUELLI, Monica, POZZI, VALENTINA, SARTINI, Davide, M Emanuelli, Emanuelli, M, M Cecati, Sartini, D, CECATI, Monia, V Pozzi   +11 more
core   +1 more source

Lactiplantibacillus Plantarum GUANKE Alleviates Allergic Asthma by Restricting Monocyte‐to‐DC Differentiation Via Microbiota‐Associated IAA

Advanced Science, EarlyView.
Lactiplantibacillus plantarum GUANKE remodels the indigenous gut microbiota and is associated with microbiota‐dependent restoration of circulating IAA. IAA treatment attenuates JAK3‐STAT3 and Jag1‐Notch4‐Hey1 signaling and reduces CX3CR1+Ly6C− monocytic precursor generation and pulmonary CD11b+ DC accumulation, together with reduced Th2 inflammation ...
Yujia He, Jielan Mi, Zhiping Zhao, Xiao Zhang, Zhihan Yang, Kun Yue, Yuanming Huang, Liqiong Song, Xiaoting Wen, Jianguo Xu, Zhihong Ren   +10 more
wiley   +1 more source

Crystal structure of a 1:1 cocrystal of nicotinamide with 2-chloro-5-nitrobenzoic acid

Acta Crystallographica Section E: Crystallographic Communications, 2019
In the title 1:1 cocrystal, C7H4ClNO4·C6H6N2O, nicotinamide (NIC) and 2-chloro-5-nitrobenzoic acid (CNBA) cocrystallize with one molecule each of NIC and CNBA in the asymmetric unit.
Keshab M. Bairagi, Priyanka Pal, Subhrajyoti Bhandary, Katharigatta N. Venugopala, Deepak Chopra, Susanta K. Nayak   +5 more
doaj   +1 more source

Kinetics of the Release of Nicotinamide Absorbed on Partially Neutralized Poly(acrylic-co-methacrylic acid) Xerogel under the Conditions of Simultaneous Microwave Heating and Cooling

Gels, 2021
The kinetics of release of nicotinamide (NIAM) that was absorbed on partially neutralized poly(acrylic-co-methacrylic) (PAM) xerogel/hydrogel, under the conditions of simultaneous microwave heating and cooling (SMHC) were examined. The kinetics curves of
Jelena D. Jovanovic, Borivoj K. Adnadjevic   +1 more
doaj   +1 more source