Results 11 to 20 of about 155,595 (297)

Biostimulants increase growth and yield of second-crop maize [PDF]

open access: yesRevista Brasileira de Engenharia Agrícola e Ambiental, 2023
The use of biostimulants in second-crop maize (Zea mays) can promote higher physiological activity in plants, resulting in higher grain yield. This study aimed to evaluate the effects of phytohormones and nicotinamide on growth and yield traits of second-
Silvia E. N. Thomé   +8 more
doaj   +1 more source

Tacrolimus nanoparticles based on chitosan combined with nicotinamide: enhancing percutaneous delivery and treatment efficacy for atopic dermatitis and reducing dose

open access: yesInternational Journal of Nanomedicine, 2017
Kaiyue Yu, Yixuan Wang, Tao Wan, Yuanhao Zhai, Sisi Cao, Wenyi Ruan, Chuanbin Wu, Yuehong Xu School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou, People’s Republic of China Background: Topical application of tacrolimus (FK506 ...
Yu K   +7 more
doaj   +1 more source

L-carnitine administration effects on AMPK, APPL1 and PPARγ genes expression in the liver and serum adiponectin levels and HOMA-IR in type 2 diabetes rat model induced by STZ and nicotinamide [PDF]

open access: yesThe Ukrainian Biochemical Journal, 2020
Diabetes is a chronic disease and a public health problem globally. L-Carnitine is synthesized in the liver, promotes fatty acids oxidation and currently is used as a supplement against weight gain.
B. Shahouzehi   +2 more
doaj   +1 more source

Identification of Biological Functions and Prognostic Value of NNMT in Oral Squamous Cell Carcinoma

open access: yesBiomolecules, 2022
Background: Nicotinamide N-methyltransferase (NNMT) is a metabolic enzyme that catalyzes the methylation of nicotinamide (NAM) to generate 1-methyl nicotinamide (MNAM).
Weixian Zhang   +11 more
doaj   +1 more source

Synthesis of Mixed Dinucleotides by Mechanochemistry

open access: yesMolecules, 2022
We report the synthesis of vitamin B1, B2, and B3 derived nucleotides and dinucleotides generated either through mechanochemical or solution phase chemistry.
Faisal Hayat   +3 more
doaj   +1 more source

The Effect of Ascorbic Acid and Nicotinamide on Panton–Valentine Leukocidin Cytotoxicity: An Ex Vivo Study

open access: yesToxins, 2023
Background: Panton–Valentine Leukocidin sustains a strong cytotoxic activity, targeting immune cells and, consequently, perforating the plasma membrane and inducing cell death.
Abdullah AlSaleh   +3 more
doaj   +1 more source

The Influence of Exercise Intensity on Tryptophan Metabolites in Thoroughbred Horses

open access: yesPharmaceuticals, 2023
Catabolism of tryptophan (Trp) is modulated by physical activity and provides a pool of active compounds: Trp is considered a calmative agent, kynurenine (Kyn) and 3-hydroxykynurenine (3-HKyn) show neurotoxic effects, kynurenic acid (Kyna) and ...
Magdalena Staniszewska   +3 more
doaj   +1 more source

Fate of Nicotinamide Differs Due to an Intake of Nicotinamide [PDF]

open access: yesBioscience, Biotechnology, and Biochemistry, 1996
We found that the catabolism of nicotinamide (Nam) differs due to an intake of Nam itself in rats. When rats were fed with a Nam-free, tryptophan-limiting diet, the major catabolite of niacin was N1-methyl-4-pyridone-3-carboxamide (4-Py). However, its percentage was changed with increasing the intake of Nam.
SHIBATA, Katsumi   +2 more
openaire   +2 more sources

Mechanistic Basis and Clinical Evidence for the Applications of Nicotinamide (Niacinamide) to Control Skin Aging and Pigmentation

open access: yesAntioxidants, 2021
Vitamin B3 (nicotinic acid, niacin) deficiency causes the systemic disease pellagra, which leads to dermatitis, diarrhea, dementia, and possibly death depending on its severity and duration.
Yong Chool Boo
doaj   +1 more source

Fibrillarin Resists Cellular Senescence Via SIRT1-Dependent Nicotinamide Metabolism and Its Inhibition Sensitizes Senolytic Therapy in Esophageal Squamous Cell Carcinoma. [PDF]

open access: yesAdv Sci (Weinh)
FBL directly binds to and stabilizes SIRT1 by blocking its ubiquitin‐proteasome degradation, thereby sustaining nicotinamide metabolism and redox homeostasis to counteract cellular senescence in ESCC. Genetic and pharmacological suppression of FBL sensitizes tumor cells to senolytic therapy.
Jin X   +9 more
europepmc   +2 more sources

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