Results 11 to 20 of about 159,186 (304)

Nicotinamide Riboside Preserves Ovarian Injury in Experimental Sepsis Model in Rats [PDF]

, 2023
Objective: The aim of the study is to investigate the protective effects of nicotinamide riboside on oxidative stress in an experimental sepsis model created by cecal ligation and puncture. Materials and Methods: Rats were divided into 3 groups randomly:
Dilek Vural Keles, Osman Nuri Keles, Keles, Osman Nuri, Vural Keles, Dilek, Yetim, Zeliha, Celik, Muhammet, Muhammet Celik, Selli, Jale, Jale Selli, Zeliha Yetim, Keles, Dilek Vural, Dilek, Vural Keleş   +11 more
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Design, Synthesis, Docking, DFT, MD Simulation Studies of a New Nicotinamide-Based Derivative: In Vitro Anticancer and VEGFR-2 Inhibitory Effects

Molecules, 2022
A nicotinamide-based derivative was designed as an antiproliferative VEGFR-2 inhibitor with the key pharmacophoric features needed to interact with the VEGFR-2 catalytic pocket.
Eslam B. Elkaeed, Reda G. Yousef, Hazem Elkady, Ibraheem M. M. Gobaara, Bshra A. Alsfouk, Dalal Z. Husein, Ibrahim M. Ibrahim, Ahmed M. Metwaly, Ibrahim H. Eissa   +8 more
doaj   +1 more source

Nicotinamide N-Methyltransferase in Head and Neck Tumors: A Comprehensive Review

Biomolecules, 2021
The head and neck tumors (HNT) are a heterogeneous group of diseases ranging from benign to malignant lesions, with distinctive molecular and clinical behaviors. Several studies have highlighted the presence of an altered metabolic phenotype in HNT, such
Lucrezia Togni, Marco Mascitti, Davide Sartini, Roberto Campagna, Valentina Pozzi, Eleonora Salvolini, Annamaria Offidani, Andrea Santarelli, Monica Emanuelli   +8 more
doaj   +1 more source

Enhanced Production of β-Nicotinamide Mononucleotide with Exogenous Nicotinamide Addition in Saccharomyces boulardii-YS01

Foods, 2023
β-Nicotinamide mononucleotide (NMN), as a key precursor of an essential coenzyme nicotinamide adenine dinucleotide (NAD+), is most recognized for its pathological treatment effects and anti-aging functions.
Meijie Song, Chunhua Yin, Qianqian Xu, Yang Liu, Haiyang Zhang, Xiaolu Liu, Hai Yan   +6 more
doaj   +1 more source

Effect of a mixture of caffeine and nicotinamide on the solubility of vitamin (B2) in aqueous solution [PDF]

, 2006
The effect of caffeine (CAF) and nicotinamide (NMD) on the solubility of a vitamin B2 derivative (FMN) has been evaluated for mixtures containing either a single hydrotrope (CAF or NMD) or the two hydrotropes simultaneously.
Davies, David B., Hernandez Santiago, A.A., Evstigneev, V.P., Evstigneev, M.P.   +3 more
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Macrocyclic Peptides as Allosteric Inhibitors of Nicotinamide N-Methyltransferase (NNMT) [PDF]

, 2020
Nicotinamide N-methyltransferase (NNMT) methylates nicotinamide to form 1-methylnicotinamide using S-adenosyl-l-methionine (SAM) as the methyl donor. The complexity of the role of NNMT in healthy and disease states is slowly being elucidated and provides
Nathaniel, Martin, Ned, Buijs, Monica, Emanuelli, Vito, Thijssen, Seino, Jongkees, Matthijs, J. van Haren, Davide, Sartini, Yurui, Zhang   +7 more
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Deracemization of Axially Chiral Nicotinamides by Dynamic Salt Formation with Enantiopure Dibenzoyltartaric Acid (DBTA)

Molecules, 2013
Dynamic atroposelective resolution of chiral salts derived from oily racemic nicotinamides and enantiopure dibenzoyltartaric acid (DBTA) was achieved by crystallization.
Fumitoshi Yagishita, Norifumi Kamataki, Kazuma Okamoto, Shota Kanno, Takashi Mino, Hyuma Masu, Masami Sakamoto   +6 more
doaj   +1 more source

TLR7 Agonist GS–9620 Combined with Nicotinamide Generate Viral Reactivation in Seronegative SHIV_SF162P3-Infected Rhesus Monkeys

Biomedicines, 2023
Antiretroviral therapy is capable of inhibiting HIV replication, but it fails to completely achieve a cure due to HIV persistence. The commonly used HIV cure approach is the “shock and kill” strategy, which employs latency-reversing agents to trigger ...
Zhe Cong, Yuting Sun, Cui Dang, Chenbo Yang, Jingjing Zhang, Jiahan Lu, Ting Chen, Qiang Wei, Wei Wang, Jing Xue   +9 more
doaj   +1 more source

Nicotinamide

Reactions Weekly
Abstract Nicotinamide (vitamin B3, Niacinamide) is a water-soluble NAD⁺/NADP⁺ precursor central to epidermal energy metabolism and cutaneous homeostasis. As an ingestible nutricosmetic, a 10 mg/day dose (~66% U.S. DV) provides a functionally active yet well-tolerated intake that supports multiple skin targets.
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Cofactor regeneration by a soluble pyridine nucleotide transhydrogenase for biological production of hydromorphone [PDF]

, 2000
We have applied the soluble pyridine nucleotide transhydrogenase of Pseudomonas fluorescens to a cell-free system for the regeneration of the nicotinamide cofactors NAD and NADP in the biological production of the important semisynthetic opiate drug ...
French, C E, Walker, E H, Bruce, N C, Rathbone, D A, Boonstra, B   +4 more
core   +1 more source