Results 11 to 20 of about 125,589 (257)
Pellagra From Tryptophan Depletion in Carcinoid Syndrome due to a Pulmonary Atypical Carcinoid Neuroendocrine Tumor [PDF]
Clinical Case ReportsPellagra may complicate functioning pulmonary atypical carcinoid and present as a subtle acral dermatosis rather than the classical photo‐distributed rash.
Ahmar Iftikhar Talib +2 more
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Nicotinamide Improves Cognitive Function in Mice With Chronic Cerebral Hypoperfusion
Frontiers in Neurology, 2021 Normal brain function requires steady blood supply to maintain stable energy state. When blood supply to the brain becomes suboptimal for a long period of time, chronic cerebral hypoperfusion (CCH) and a variety of brain changes may occur.
Bin Liu +3 more
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Biomedicines, 2023 Obesity-induced insulin resistance is among the key factors in the development of type 2 diabetes, atherogenic dyslipidemia and cardiovascular disease. Adipose tissue plays a key role in the regulation of whole-body metabolism and insulin sensitivity. In
Tatjana Ruskovska, David A. Bernlohr
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Biomedicines, 2023 (1) Background: Inducing experimental stroke leads to biphasic immune responses, where the early activation of immune functions is followed by severe immunosuppression accompanied by spleen and thymus atrophy.
Shih-Huang Tai +6 more
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The Anion Impact on Dimensionality of Cadmium(II) Complexes with Nicotinamide
Chemistry, 2023 Three novel cadmium(II) coordination compounds, the dimeric [Cd(CH3COO)2(nia)2]2 (1), the polymeric {[Cd(nia)4](ClO4)2}n (2), and the monomeric [Cd(H2O)3(nia)3](ClO4)2·nia (3), were prepared in the reactions of the nicotinamide (pyridine-3-carboxamide ...
Željka Soldin +4 more
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Amyotrophic lateral sclerosis and intestinal microbiota—toward establishing cause and effect
Gut Microbes, 2020 The intestinal microbiota may be involved, through metabolic gut–brain interactions, in a variety of neurological conditions. In this addendum, we summarize the findings of our recent study investigating the potentially modulatory influence of the ...
Marc Gotkine +2 more
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Design and Activity of Novel Oxadiazole Based Compounds That Target Poly(ADP-ribose) Polymerase
Molecules, 2022 Novel PARP inhibitors with selective mode-of-action have been approved for clinical use. Herein, oxadiazole based ligands that are predicted to target PARP-1 have been synthesized and screened for the loss of cell viability in mammary carcinoma cells ...
Divakar Vishwanath +7 more
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Reactions WeeklyAbstract Nicotinamide (vitamin B3, Niacinamide) is a water-soluble NAD⁺/NADP⁺ precursor central to epidermal energy metabolism and cutaneous homeostasis. As an ingestible nutricosmetic, a 10 mg/day dose (~66% U.S. DV) provides a functionally active yet well-tolerated intake that supports multiple skin targets.
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Marine Drugs, 2018 Nicotinamide (NA), a water-soluble vitamin B3, has been shown to exert cellular-protective effects against reactive oxygen species (ROS). In order to improve the cellular-protective effects of NA, we synthesized a novel compound, nicotinyl&ndash ...
Dong Hwee Son +10 more
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The Prospective Synergy of Antitubercular Drugs With NAD Biosynthesis Inhibitors
Frontiers in Microbiology, 2021 Given the upsurge of drug-resistant tuberculosis worldwide, there is much focus on developing novel drug combinations allowing shorter treatment duration and a lower toxicity profile.
Kyle H. Rohde, Leonardo Sorci
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