Results 51 to 60 of about 256,874 (388)
NADomics: Measuring NAD+ and Related Metabolites Using Liquid Chromatography Mass Spectrometry
Nicotinamide adenine dinucleotide (NAD+) and its metabolome (NADome) play important roles in preserving cellular homeostasis. Altered levels of the NADome may represent a likely indicator of poor metabolic function.
Nady Braidy+2 more
doaj +1 more source
The kinetics of release of nicotinamide (NIAM) that was absorbed on partially neutralized poly(acrylic-co-methacrylic) (PAM) xerogel/hydrogel, under the conditions of simultaneous microwave heating and cooling (SMHC) were examined. The kinetics curves of
Jelena D. Jovanovic+1 more
doaj +1 more source
doi: http://dx.doi.org/10.15407/ubj86.04.138 [PDF]
Connective tissue is highly susceptible to imbalances induced by diabetes. Diabetes-related osteopenia, decreased bone strength etc. may be associated with altered metabolism of various collagens. Although it is assumed that alterations in collagen amino
M. M. Guzyk+4 more
doaj +1 more source
Pyrroloquinoline quinone increases the expression and activity of Sirt1 and -3 genes in HepG2 cells. [PDF]
Sirtuin (Sirt) 1 and Sirt 3 are nicotinamide adenine dinucleotide ((+))-dependent protein deacetylases that are important to a number of mitochondrial-related functions; thus, identification of sirtuin activators is important. Herein, we hypothesize that
Arguelles, Andrix+6 more
core +1 more source
Nicotinamide as a Foundation for Treating Neurodegenerative Disease and Metabolic Disorders.
Neurodegenerative disorders impact more than one billion individuals worldwide and are intimately tied to metabolic disease that can affect another nine hundred individuals throughput the globe.
K. Maiese
semanticscholar +1 more source
Chitin nanofibrils (CN) and nanolignin (NL) were used to embed active molecules, such as vitamin E, sodium ascorbyl phosphate, lutein, nicotinamide and glycyrrhetinic acid (derived from licorice), in the design of antimicrobial, anti-inflammatory and ...
Maria-Beatrice Coltelli+8 more
doaj +1 more source
Is a Malleable Active Site Loop the Key to High Substrate Promiscuity? Hybrid, Biocatalytic Route to Structurally Diverse Taxoid Side Chains with Remarkable Dual Stereocontrol. [PDF]
A highly stereoselective, dynamic reductive kinetic resolution (DYRKR) entry into myriad Taxotere‐like side chains with Clostridium acetobutylicum alcohol dehydrogenase (CaADH) enzyme is reported. Follow‐on cross couplings expand the structural diversity of the library (36 total examples).
Kudalkar GP+15 more
europepmc +3 more sources
Porcine epidemic diarrhea virus (PEDV) and porcine deltacoronavirus (PDCoV), members of the genus Coronavirus, mainly cause acute diarrhea, vomiting and dehydration in piglets, and thus lead to serious economic losses.
Mingxia Li+10 more
doaj +1 more source
Poly(amido amine)s as Gene Delivery Vectors: Effects of Quaternary Nicotinamide Moieties in the Side Chains [PDF]
To evaluate the effect of quaternary nicotinamide pendant groups on gene delivery properties, a series of poly(amido amine) (co)polymers were synthesized by Michael addition polymerization of N, N-cystaminebisacrylamide with variable ratios of 1-(4 ...
Engbersen, Johan F.J.+4 more
core +6 more sources
Vitamin B3 (niacin) is essential for all living cells and plays a central role in energy metabolism and oxidative phosphorylation. Vitamin B3, a water-soluble vitamin, is present in the form of nicotinic
Jale Çatak
doaj +1 more source