Nicotinamide adenine dinucleotide is transported into mammalian mitochondria
Mitochondrial NAD levels influence fuel selection, circadian rhythms, and cell survival under stress. It has alternately been argued that NAD in mammalian mitochondria arises from import of cytosolic nicotinamide (NAM), nicotinamide mononucleotide (NMN),
Antonio Davila+9 more
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Conversion of Reduced Nicotinamide-Adenine Dinucleotide Dehydrogenase into Reduced Nicotinamide-Adenine Dinucleotide-Ubiquinone Reductase [PDF]
J.I. Salach+2 more
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Nicotinamide adenine dinucleotide as a photocatalyst [PDF]
Nicotinamide adenine dinucleotide functions as a molecular photocatalyst, distinct from its pivotal roles in biological processes.
Jinhyun Kim+5 more
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Adenine Nucleotide and Nicotinamide Adenine Dinucleotide Measurements in Plants [PDF]
AbstractAs the principal co‐factors of many metabolic pathways, the measurement of both adenine nucleotides and nicotinamide adenine dinucleotide provides important information about cellular energy metabolism. However, given their rapid and reversible conversion as well as their relatively low concentration ranges, it is difficult to measure these ...
Zhang, Youjun+4 more
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Measurement of nicotinamide adenine dinucleotide & nicotinamide adenine dinucleotide phosphate in tomato leaves [PDF]
As part of an investigation of the growth of tomato plants supplied with either nitrate or ammonium nitrogen (6), leaves were assayed for NAD4 and NADP. Anderson and Vennesland (1) assayed NAD and NADP in various green tissues and reported recoveries between 50 % and 85 % of NAD and NADP added to spinach leaf extracts.
Janet SD Graham, J. S. Hawker
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ChemInform Abstract: The Oxidized Form of Nicotinamide Adenine Dinucleotide. [PDF]
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Guillot, Benoit+2 more
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A Fluorescent Analog of Nicotinamide Adenine Dinucleotide [PDF]
Nicotinamide 1, N 6 -ethenoadenine dinucleotide, a fluorescent analog of the coenzyme nicotinamide adenine dinucleotide, has been synthesized by the reaction of chloroacetaldehyde with the coenzyme. The technical fluorescence emission maximum of the analog is 410 nm, upon excitation at 300 nm.
Nelson J. Leonard+2 more
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Abstract Rat liver NAD kinase (ATP:NAD 2'-phosphotransferase, EC 2.7.1.23) was purified about 70-fold. The Michaelis-Menten constants (Km) for NAD and ATP were 8 x 10-4 m and 2 x 10-3 m, respectively. NAD kinase activity was markedly inhibited by NADH and also NADPH.
Hiroshi Oka, J. B. Field
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Nicotinamide Adenine Dinucleotide Metabolism and Neurodegeneration [PDF]
Nicotinamide adenine dinucleotide (NAD+) participates in redox reactions and NAD+-dependent signaling processes, which involve the cleavage of NAD+ coupled to posttranslational modifications of proteins or the production of second messengers. Either as a primary cause or as a secondary component of the pathogenic process, mitochondrial dysfunction and ...
Kelby M. Killoy+3 more
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It takes two to tango: NAD+ and sirtuins in aging/longevity control [PDF]
The coupling of nicotinamide adenine dinucleotide (NAD+) breakdown and protein deacylation is a unique feature of the family of proteins called ‘sirtuins.’ This intimate connection between NAD+ and sirtuins has an ancient origin and provides a ...
Guarente, Leonard, Imai, Shin-ichiro
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