Results 41 to 50 of about 90,416 (304)

Nicotinamide adenine dinucleotide treatment confers resistance to neonatal ischemia and hypoxia: effects on neurobehavioral phenotypes

Neural Regeneration Research
Neonatal hypoxic-ischemic brain injury is the main cause of hypoxic-ischemic encephalopathy and cerebral palsy. Currently, there are few effective clinical treatments for neonatal hypoxic-ischemic brain injury.
Xiaowen Xu, Xinxin Wang, Li Zhang, Yiming Jin, Lili Li, Meifang Jin, Lianyong Li, Hong Ni   +7 more
doaj   +1 more source

Early Evolutionary Selection of NAD Biosynthesis Pathway in Bacteria

Metabolites, 2022
Bacteria use two alternative pathways to synthesize nicotinamide adenine dinucleotide (NAD) from nicotinamide (Nam). A short, two-step route proceeds through nicotinamide mononucleotide (NMN) formation, whereas the other pathway, a four-step route ...
Suraj Sharma, Yin-Chen Hsieh, Jörn Dietze, Mathias Bockwoldt, Øyvind Strømland, Mathias Ziegler, Ines Heiland   +6 more
doaj   +1 more source

Nicotinamide adenine dinucleotide (reduced)

, 2017
Inelastic Neutron Scattering spectrum of Nicotinamide adenine dinucleotide (reduced), C₆H₆N₂O, measured on the TFXA ...
R. E. Hester, University of York
core   +1 more source

Nicotinamide adenine dinucleotide (oxidised)

, 2017
Inelastic Neutron Scattering spectrum of Nicotinamide adenine dinucleotide (oxidised), C₆H₆N₂O, measured on the TFXA ...
R. E. Hester, UNiversity of York
core   +1 more source

Nicotinamide adenine dinucleotide is transported into mammalian mitochondria

eLife, 2018
Mitochondrial NAD levels influence fuel selection, circadian rhythms, and cell survival under stress. It has alternately been argued that NAD in mammalian mitochondria arises from import of cytosolic nicotinamide (NAM), nicotinamide mononucleotide (NMN),
Antonio Davila, Ling Liu, Karthikeyani Chellappa, Philip Redpath, Eiko Nakamaru-Ogiso, Lauren M Paolella, Zhigang Zhang, Marie E Migaud, Joshua D Rabinowitz, Joseph A Baur   +9 more
doaj   +1 more source

Inhibition of Nicotinamidase by Nicotinamide Adenine Dinucleotide

Journal of Biological Chemistry, 1971
Abstract Feedback inhibition by NAD was shown with the nicotinamidases of a number of microorganisms. The purified enzyme from Fleischmann's yeast was found to have a molecular weight of 110,000 and consist of presumably identical subunits with a molecular weight of 26,000.
D F, Calbreath, J G, Joshi
openaire   +2 more sources

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Cellular nicotinamide adenine dinucleotide (NADH) as an indicator of bacterial metabolic activity dynamics in activated sludge

, 2009
In this study, native fluorescent nicotinamide adenine dinucleotide (NADH) was used as a direct indicator of bacterial metabolic activity in activated sludge. Specific NADH concentration was dynamic and varied between 106-108 molecules per bacterial cell.
Pollard, PC, Pollard, Peter, L Wos, M., Wos, ML   +3 more
core   +1 more source

High-Throughput Screening of a 2-Keto-L-Gulonic Acid-Producing Gluconobacter oxydans Strain Based on Related Dehydrogenases

Frontiers in Bioengineering and Biotechnology, 2019
High-throughput screening is a powerful tool for discovering strains in the natural environment that may be suitable for target production. Herein, a novel enzyme-based high-throughput screening method was developed for rapid screening of strains ...
Yue Chen, Yue Chen, Yue Chen, Li Liu, Li Liu, Li Liu, Xiaoyu Shan, Xiaoyu Shan, Xiaoyu Shan, Guocheng Du, Guocheng Du, Jingwen Zhou, Jingwen Zhou, Jingwen Zhou, Jian Chen, Jian Chen   +15 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source