Results 41 to 50 of about 134,103 (347)

Decreased myocardial injury and improved contractility after administration of a peptide derived against the alpha-interacting domain of the L-type calcium channel. [PDF]

, 2014
BackgroundMyocardial infarction remains the leading cause of morbidity and mortality associated with coronary artery disease. The L-type calcium channel (IC a-L) is critical to excitation and contraction.
Hool, Livia C, Jordan, Maria C, Roos, Kenneth P, Viola, Helena M   +3 more
core   +1 more source

Light-Induced Conversion of Nicotinamide Adenine Dinucleotide to Nicotinamide Adenine Dinucleotide Phosphate in Higher Plant Leaves [PDF]

Plant Physiology, 1981
Light-induced conversion of NAD to NADP was investigated in higher plants. Upon illumination, conversion of NAD to NADP was observed in intact leaves of wheat and pea following incubation in the dark. This conversion was also observed in mesophyll protoplasts of wheat leaves when they were isolated in the dark or isolated in light and then preincubated
James A. Bassham, Gerald E. Edwards, Shoshi Muto, Shigetoh Miyachi, Hideaki Usuda   +4 more
openaire   +3 more sources

Degradation of reactive red 195 by selected bacteria from textile wastewater [PDF]

, 2009
Four selected bacterial strains coded R1, R2, Rc and Rd were successfully isolated from raw textile wastewater. They were screened for their ability to degrade an azo dye of Reactive Red 195 on solid and in liquid dye-containing media.
Nawahwi, Mohd. Zaini
core  

Inhibition of Nicotinamidase by Nicotinamide Adenine Dinucleotide

Journal of Biological Chemistry, 1971
Abstract Feedback inhibition by NAD was shown with the nicotinamidases of a number of microorganisms. The purified enzyme from Fleischmann's yeast was found to have a molecular weight of 110,000 and consist of presumably identical subunits with a molecular weight of 26,000.
D.F. Calbreath, Jayant G. Joshi
openaire   +3 more sources

The nicotinamide hypothesis revisited—plant defense signaling integrating PARP, nicotinamide, nicotinic acid, epigenetics, and glutathione

FEBS Letters, EarlyView.
Nicotinamide (NIC) and nicotinic acid (NIA) are proposed as stress signaling compounds in plants. Oxidative stress may lead to single strand breaks (SSB) in DNA, which activate poly(ADP‐ribose) polymerase (PARP). NIC and NIA are then formed from NAD. NIC and NIA can promote epigenetic changes leading to the expression of defense genes specific for the ...
Torkel Berglund, Anna B. Ohlsson
wiley   +1 more source

High-Throughput Screening of a 2-Keto-L-Gulonic Acid-Producing Gluconobacter oxydans Strain Based on Related Dehydrogenases

Frontiers in Bioengineering and Biotechnology, 2019
High-throughput screening is a powerful tool for discovering strains in the natural environment that may be suitable for target production. Herein, a novel enzyme-based high-throughput screening method was developed for rapid screening of strains ...
Yue Chen, Yue Chen, Yue Chen, Li Liu, Li Liu, Li Liu, Xiaoyu Shan, Xiaoyu Shan, Xiaoyu Shan, Guocheng Du, Guocheng Du, Jingwen Zhou, Jingwen Zhou, Jingwen Zhou, Jian Chen, Jian Chen   +15 more
doaj   +1 more source

Dysregulation of NAD+ metabolism induces a Schwann cell dedifferentiation program [PDF]

, 2018
The Schwann cell (SC) is the major component of the peripheral nervous system (PNS) that provides metabolic and functional support for peripheral axons. The emerging roles of SC mitochondrial function for PNS development and axonal stability indicate the
Hackett, Amber R, Kim, Sungsu, Milbrandt, Jeffrey, Sasaki, Yo, Strickland, Amy   +4 more
core   +1 more source

Central Dysmyelination in SSADH‐Deficient Humans and Mice

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Succinic semialdehyde dehydrogenase deficiency (SSADHD) is an inherited metabolic disorder characterized by an accumulation of γ‐aminobutyric (GABA). In addition to its synaptic role as an inhibitory neurotransmitter, GABA also plays an important role in myelination.
Itay Tokatly Latzer, Henry H. C. Lee, Edward Yang, Cesar Alves, Mariarita Bertoldi, Caitlyn Fung, Spencer V. Steele, Eren Kule, Zijie Jin, Alexander Rotenberg, Jean‐Baptiste Roullet, Phillip L. Pearl   +11 more
wiley   +1 more source

Mechanisms of Alcoholic Liver Injury

Canadian Journal of Gastroenterology, 2000
There have been numerous recent advances in the understanding of the mechanisms of alcoholic liver disease pathogenesis. Endotoxin-induced Kupffer cell activation plays a role in cytokine-mediated inflammatory changes in the liver, and this can be ...
Samuel W French
doaj   +1 more source

Measuring CD38 Hydrolase and Cyclase Activities: 1,N6-Ethenonicotinamide Adenine Dinucleotide (ε-NAD) and Nicotinamide Guanine Dinucleotide (NGD) Fluorescence-based Methods

Bio-Protocol, 2018
CD38 is a multifunctional enzyme involved in calcium signaling and Nicotinamide Adenine Dinucleotide (NAD+) metabolism. Through its major activity, the hydrolysis of NAD+, CD38 helps maintain the appropriate levels of this molecule for all NAD+-dependent
Guilherme de Oliveira, Karina Kanamori, Maria Auxiliadora-Martins, Claudia Chini, Eduardo Chini   +4 more
doaj   +1 more source