Results 121 to 130 of about 170,260 (319)

Synthetic nicotine e-liquids sold in US online vape shops

open access: yesPreventive Medicine Reports, 2023
Synthetic nicotine (relative to tobacco-derived, or “natural” nicotine) is an emerging feature of e-cigarettes including e-liquids in the online marketplace. This study investigated a total of 11,161 unique nicotine e-liquids sold in online stores in the
Shaoying Ma   +3 more
doaj  

Direct genetic effects and their estimation from matched case-control data [PDF]

open access: yesarXiv, 2011
In genetic association studies, a single marker is often associated with multiple, correlated phenotypes (e.g., obesity and cardiovascular disease, or nicotine dependence and lung cancer). A pervasive question is then whether that marker has independent effects on all phenotypes. In this article, we address this question by assessing whether there is a
arxiv  

PAK3 pathogenic variant associated with sleep‐related hypermotor epilepsy in a family with parental mosaicism

open access: yesEpilepsia Open, EarlyView.
Abstract Protein‐activated kinases mediate spine morphogenesis and synaptic plasticity. PAK3 is part of the p21‐activated kinases (PAKs) family of Ras‐signaling serine/threonine kinases. Pathogenic variants in the X‐linked gene PAK3 have been described in patients with neurodevelopmental syndromes.
Antonio Gambardella   +12 more
wiley   +1 more source

Computational neuroanatomy and co-expression of genes in the adult mouse brain, analysis tools for the Allen Brain Atlas [PDF]

open access: yesarXiv, 2013
We review quantitative methods and software developed to analyze genome-scale, brain-wide spatially-mapped gene-expression data. We expose new methods based on the underlying high-dimensional geometry of voxel space and gene space, and on simulations of the distribution of co-expression networks of a given size.
arxiv  

Personality Functioning in Inpatients With Eating Disorders: Association With Symptom Severity and Treatment Outcome

open access: yesEuropean Eating Disorders Review, EarlyView.
ABSTRACT Objective Impairment in personality functioning (PF) has been linked to a number of mental disorders, including eating disorders (EDs). However, the precise relationship between PF and symptom severity, as well as the potential impact on outcome, remains unclear.
Sophia Heinzmann   +45 more
wiley   +1 more source

Isolation and characterization of extracellular vesicles and future directions in diagnosis and therapy

open access: yesWIREs Nanomedicine and Nanobiotechnology, Volume 15, Issue 1, January/February 2023., 2023
Fundamental research on EV isolation, standardization and characterisation will bring about translational medical diagnostics and therapy. Abstract Extracellular vesicles (EVs) are a unique and heterogeneous class of lipid bilayer nanoparticles secreted by most cells.
Karina P. De Sousa   +5 more
wiley   +1 more source

Is it the nicotine or the tobacco?

open access: yesBulletin of the World Health Organization, 2000
Recentyearshaveseenagrowingrecognitionthatproductregulationiscriticaltodealingeffectivelywiththetobaccoepidemic.Itisalsonowwidelyrecognizedthat,thoughitisthenicotinethatcausesdependence, tobacco products (which can becharacterized as particularly ‘dirty’ drug deliverydevices)areresponsibleforthevastmajorityofthedamage to health.
openaire   +5 more sources

Subculture wars: The struggle for the vape industry

open access: yesThe British Journal of Sociology, Volume 74, Issue 1, Page 3-16, January 2023., 2023
Abstract Drawing on a 2‐year study, I argue that the UK vape industry is engaged in a classificatory struggle between a subcultural industry and its “other”, the mainstream industry. I build on Thornton's analysis of club culture to characterize the subcultural vape industry as a community of taste built round a masculine aesthetic and a commitment to ...
Frances Thirlway
wiley   +1 more source

Cytotoxicity of 19 Pesticides in Rainbow Trout Gill, Liver, and Intestinal Cell Lines

open access: yesEnvironmental Toxicology and Chemistry, EarlyView.
Abstract The rainbow trout gill cell line (RTgill‐W1), via test guideline 249 of the Organisation for Economic Co‐operation and Development, has been established as a promising New Approach Methodology, although to advance confidence in the method more case studies are needed that: 1) expand our understanding of applicability domains (chemicals with ...
Sophie Emberley‐Korkmaz   +4 more
wiley   +1 more source

Cardiac Effects of Intracoronary Arterial Injections of Nicotine [PDF]

open access: bronze, 1958
James W. West   +2 more
openalex   +1 more source

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