Results 121 to 130 of about 170,260 (319)
Synthetic nicotine e-liquids sold in US online vape shops
Synthetic nicotine (relative to tobacco-derived, or “natural” nicotine) is an emerging feature of e-cigarettes including e-liquids in the online marketplace. This study investigated a total of 11,161 unique nicotine e-liquids sold in online stores in the
Shaoying Ma+3 more
doaj
Direct genetic effects and their estimation from matched case-control data [PDF]
In genetic association studies, a single marker is often associated with multiple, correlated phenotypes (e.g., obesity and cardiovascular disease, or nicotine dependence and lung cancer). A pervasive question is then whether that marker has independent effects on all phenotypes. In this article, we address this question by assessing whether there is a
arxiv
Abstract Protein‐activated kinases mediate spine morphogenesis and synaptic plasticity. PAK3 is part of the p21‐activated kinases (PAKs) family of Ras‐signaling serine/threonine kinases. Pathogenic variants in the X‐linked gene PAK3 have been described in patients with neurodevelopmental syndromes.
Antonio Gambardella+12 more
wiley +1 more source
Computational neuroanatomy and co-expression of genes in the adult mouse brain, analysis tools for the Allen Brain Atlas [PDF]
We review quantitative methods and software developed to analyze genome-scale, brain-wide spatially-mapped gene-expression data. We expose new methods based on the underlying high-dimensional geometry of voxel space and gene space, and on simulations of the distribution of co-expression networks of a given size.
arxiv
ABSTRACT Objective Impairment in personality functioning (PF) has been linked to a number of mental disorders, including eating disorders (EDs). However, the precise relationship between PF and symptom severity, as well as the potential impact on outcome, remains unclear.
Sophia Heinzmann+45 more
wiley +1 more source
Fundamental research on EV isolation, standardization and characterisation will bring about translational medical diagnostics and therapy. Abstract Extracellular vesicles (EVs) are a unique and heterogeneous class of lipid bilayer nanoparticles secreted by most cells.
Karina P. De Sousa+5 more
wiley +1 more source
Is it the nicotine or the tobacco?
Recentyearshaveseenagrowingrecognitionthatproductregulationiscriticaltodealingeffectivelywiththetobaccoepidemic.Itisalsonowwidelyrecognizedthat,thoughitisthenicotinethatcausesdependence, tobacco products (which can becharacterized as particularly ‘dirty’ drug deliverydevices)areresponsibleforthevastmajorityofthedamage to health.
openaire +5 more sources
Subculture wars: The struggle for the vape industry
Abstract Drawing on a 2‐year study, I argue that the UK vape industry is engaged in a classificatory struggle between a subcultural industry and its “other”, the mainstream industry. I build on Thornton's analysis of club culture to characterize the subcultural vape industry as a community of taste built round a masculine aesthetic and a commitment to ...
Frances Thirlway
wiley +1 more source
Cytotoxicity of 19 Pesticides in Rainbow Trout Gill, Liver, and Intestinal Cell Lines
Abstract The rainbow trout gill cell line (RTgill‐W1), via test guideline 249 of the Organisation for Economic Co‐operation and Development, has been established as a promising New Approach Methodology, although to advance confidence in the method more case studies are needed that: 1) expand our understanding of applicability domains (chemicals with ...
Sophie Emberley‐Korkmaz+4 more
wiley +1 more source
Cardiac Effects of Intracoronary Arterial Injections of Nicotine [PDF]
James W. West+2 more
openalex +1 more source