Results 11 to 20 of about 297,452 (281)

Nicotine Addiction [PDF]

open access: yesNew England Journal of Medicine, 1999
Nicotine maintains tobacco addiction. Nicotine acts on nicotinic cholinergic receptors, which demonstrate diversity in subunit structure, function, and distribution in the nervous system, mediating the multiple actions of nicotine described in tobacco users.
openaire   +3 more sources

Longitudinal analysis of cigar use patterns among US youth and adults, 2013–2019

open access: yesBMC Public Health, 2023
Background Cigars are available in a range of pack quantities, which contrasts regulations requiring cigarettes to be sold in packs of 20 or greater. Smaller packages may be associated with increases in initiation while larger packs may lead consumers to
Jessica King Jensen   +4 more
doaj   +1 more source

E-cigarette prevalence among Malaysian adults and types and flavors of e-cigarette products used by cigarette smokers who vape: Findings from the 2020 ITC Malaysia Survey

open access: yesTobacco Induced Diseases, 2022
Introduction E-cigarettes (ECs) have become increasingly common in many countries, including Malaysia. The prevalence of EC use increased in Malaysia from 0.8% in 2011 to 4.9% in 2019.
Pete Driezen   +13 more
doaj   +1 more source

Comparative cytotoxicity study of nicotine and cotinine on MRC-5 cell line [PDF]

open access: yes, 2018
Nicotine has several health hazards regarding carcinogenic potential. It also imparts increased risk for respiratory, cardiovascular, and gastrointestinal disorders.
Baconi, Daniela Luiza   +4 more
core   +4 more sources

Nicotine Withdrawal [PDF]

open access: yes, 2015
An aversive abstinence syndrome manifests 4-24 h following cessation of chronic use of nicotine-containing products. Symptoms peak on approximately the 3rd day and taper off over the course of the following 3-4 weeks. While the severity of withdrawal symptoms is largely determined by how nicotine is consumed, certain short nucleotide polymorphisms ...
Ian, McLaughlin   +2 more
openaire   +2 more sources

Cocreation of a conversational agent to help patients adhere to their varenicline treatment: A study protocol

open access: yesDigital Health, 2023
Objective Varenicline is the most efficacious approved smoking cessation medication, making it one of the most cost-effective clinical interventions for reducing tobacco-related morbidity and mortality. Adhering to varenicline is strongly associated with
Nadia Minian   +7 more
doaj   +1 more source

Why do smokers use e-cigarettes? A study on reasons among dual users

open access: yesPreventive Medicine Reports, 2022
Objective: There is minimal research that has measured motivations behind e-cigarette use and the relationship to cigarette and e-cigarette use. The aim of this study was to (1) examine extent to which motivations to use e-cigarettes varies among dual ...
Allison A. Temourian   +4 more
doaj   +1 more source

Nicotine strongly activates dendritic cell-mediated adaptive immunity - potential role for progression of atherosclerotic lesions [PDF]

open access: yes, 2003
Background - Antigen-presenting cells (APCs) such as monocytes and dendritic cells (DCs) stimulate T-cell proliferation and activation in the course of adaptive immunity.
Aicher, A   +5 more
core   +1 more source

The effect of a clinical decision support system on prompting an intervention for risky alcohol use in a primary care smoking cessation program: a cluster randomized trial

open access: yesImplementation Science, 2019
Background Clinical decision support systems (CDSSs) may promote practitioner adherence to evidence-based guidelines. This study examined if the addition of a CDSS influenced practitioner delivery of a brief intervention with treatment-seeking smokers ...
Nadia Minian   +9 more
doaj   +1 more source

Pharmacokinetic differences in nicotine and nicotine salts mediate reinforcement-related behavior: an animal model study

open access: yesFrontiers in Neuroscience, 2023
Since their introduction in the United States and Europe in 2007, electronic cigarettes (E-Cigs) have become increasingly popular among smokers. Nicotine, a key component in both tobacco and e-cigarettes, can exist in two forms: nicotine-freebase (FBN ...
Pengfei Han   +36 more
doaj   +1 more source

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