Results 31 to 40 of about 170,260 (319)

Personalized dosing of nicotine replacement therapy versus standard dosing for the treatment of individuals with tobacco dependence: study protocol for a randomized placebo-controlled trial

Trials, 2020
Background Medications for smoking cessation are currently only effective in helping a minority of smokers quit. Drug development is slow and expensive; as such, there is much interest in optimizing the effectiveness of existing treatments and ...
Laurie Zawertailo, Christian S. Hendershot, Rachel F. Tyndale, Bernard Le Foll, Andriy V. Samokhvalov, Kevin E. Thorpe, Andrew Pipe, Robert D. Reid, Peter Selby   +8 more
doaj   +1 more source

Identification of nicotine-seeking and avoiding larval zebrafish using a new three-choice behavioral assay

Frontiers in Molecular Neuroscience, 2023
IntroductionNicotine dependence is one of the main causes of preventable diseases in the United States. Nicotine-seeking and avoidance behavioral assays in larval zebrafish could be used for identifying potential new pharmacotherapeutics in an early ...
Henning Schneider, Anna Pearson, Drew Harris, Sabrina Krause, Andrew Tucker, Kaitlyn Gardner, Kuzivakwashe Chinyanya   +6 more
doaj   +1 more source

Perceptions of COVID-related risks among people who smoke: A mediation model

Preventive Medicine Reports, 2023
The COVID-19 pandemic provides both reasons to quit smoking as well as stress that may promote increased cigarette consumption. Perceptions of COVID-19 risk related to smoking may motivate cessation among smokers.
Deanna M. Halliday, Anna E. Epperson, Mariaelena Gonzalez, Anna V. Song   +3 more
doaj  

Differences in nicotine metabolism of two Nicotiana attenuata herbivores render them differentially susceptible to a common native predator. [PDF]

PLoS ONE, 2014
Nicotiana attenuata is attacked by larvae of both specialist (Manduca sexta) and generalist (Spodoptera exigua) lepidopteran herbivores in its native habitat. Nicotine is one of N. attenuata's important defenses. M.
Pavan Kumar, Preeti Rathi, Matthias Schöttner, Ian T Baldwin, Sagar Pandit   +4 more
doaj   +1 more source

Comparative evaluation of the efficacy of nicotine chewing gum and nicotine patches as nicotine replacement therapy using salivary cotinine levels as a biochemical validation measure

Indian Journal of Psychiatry, 2023
Background: Nicotine replacement therapy (NRT) and habit cessation counseling are considered the mainstay treatment for high nicotine dependence smokers. However, adherence to NRT is very poor.
T Sivasankari, Avudaiappan Sankaran, Senthil Murugappan, Veni Subramanyam, Balanehru Subramanian, RC Jagat Reddy, S Vandana   +6 more
doaj   +1 more source

Resolution of complex fluorescence spectra of lipids and nicotinic acetylcholine receptor by multivariate analysis reveals protein-mediated effects on the receptor's immediate lipid microenvironment [PDF]

PMC Biophysics 2008, 1:6, 2009
Analysis of fluorescent spectra from complex biological systems containing various fluorescent probes with overlapping emission bands is a challenging task. Valuable information can be extracted from the full spectra, however, by using multivariate analysis (MA) of measurements at different wavelengths.
arxiv   +1 more source

Thermal properties and kinetic analysis of pyrolysis products of nicotine salts from e-cigarettes using pyrolysis-gas chromatography/mass spectrometry

Frontiers in Environmental Science, 2023
Volatile organic chemicals (VOCs) released from e-cigarettes are a special source of air pollutants. In this work, we investigated the VOCs released from six nicotine salts (namely, nicotine benzoate, nicotine tartrate, nicotine citrate, nicotine malate,
Ji Yang, Yirong Li, Yirong Li, Chunbo Liu, Shiyun Tang, Zhengjie Li, Lihong Jiang   +6 more
doaj   +1 more source

Spontaneous Lipid Binding to the Nicotinic Acetylcholine Receptor in a Native Membrane [PDF]

, 2021
The nicotinic acetylcholine receptor (nAChR) and other pentameric ligand-gated ion channels (pLGICs) are native to neuronal membranes with an unusual lipid composition. While it is well-established that these receptors can be significantly modulated by lipids, the underlying mechanisms have been primarily studied in model membranes with only a few ...
arxiv   +1 more source

An integrated digital/clinical approach to smoking cessation in lung cancer screening: study protocol for a randomized controlled trial

Trials, 2017
Background Delivering effective tobacco dependence treatment that is feasible within lung cancer screening (LCS) programs is crucial for realizing the health benefits and cost savings of screening.
Amanda L. Graham, Michael V. Burke, Megan A. Jacobs, Sarah Cha, Ivana T. Croghan, Darrell R. Schroeder, James P. Moriarty, Bijan J. Borah, Donna F. Rasmussen, M. Jody Brookover, Dale B. Suesse, David E. Midthun, J. Taylor Hays   +12 more
doaj   +1 more source

Identification and Quantitation of Nicotine Polacrilex in Nicotine Pouches and Other Oral Nicotine Delivery Products

Contributions to Tobacco and Nicotine Research, 2023
Nicotine polacrilex (CAS-No. 96055-45-7) can be used as the source of nicotine in nicotine pouches and other oral nicotine delivery products such as lozenges, tablets, and gums.
Moldoveanu Serban C.
doaj   +1 more source