Results 81 to 90 of about 265,934 (241)
Autism Research, EarlyView.ABSTRACT Exogenous prenatal exposures may affect neurodevelopment across multiple generations. We investigated grandmother and grandfather smoking, alcohol, coffee, and tea consumption during pregnancy in relation to their grandchildren's risk of autism spectrum disorder (ASD).
Michelle Pearl +6 more
wiley +1 more source
Development of a nalmefene formulation suitable for a community‐use auto‐injector
British Journal of Clinical Pharmacology, EarlyView.Aim Time to onset of reversal is critical when treating opioid‐induced respiratory depression and hypoxia. This study aimed to develop a formulation of the opioid antagonist nalmefene with an increased absorption rate and reduced time to onset of reversal following intramuscular administration. Methods Several absorption enhancers were screened in rats,
Alessandra Cipriano +6 more
wiley +1 more source
British Journal of Clinical Pharmacology, EarlyView.Study design and main findings. After 1:1 propensity score matching, 60 885 PCSK9 inhibitor users and 60 885 statin‐only users with ASCVD were compared. Kaplan–Meier curves show 12‐month cumulative event‐free survival for MACE, psychiatric disease, and neurodegenerative disease.
Tianshu Gu +7 more
wiley +1 more source
Neurotensin Agonist Attenuates Nicotine Potentiation to Cocaine Sensitization
Behavioral Sciences, 2014 Tobacco usage typically precedes illicit drug use in adolescent and young adult populations. Several animal studies suggest nicotine increases the risk for subsequent cocaine abuse, and may be a negative prognostic factor for treatment of cocaine ...
Paul Fredrickson +3 more
doaj +1 more source
British Journal of Clinical Pharmacology, EarlyView.Improvement in medication adherence is often proposed as a potential advantage of pharmacogenetic‐guided prescribing over a traditional one‐size‐fits‐all approach. This paper provides a review of the published literature and presents the findings of studies that measure adherence to medication as an outcome of pharmacogenetic‐informed care, or that ...
Lucy Galloway +2 more
wiley +1 more source
Effective Treatments for Nicotine Addiction [PDF]
, 2020 Nicotine dependence as a result of smoking is a chronically relapsing disorder with detrimental effects. However, fortunately for smokers, an armamentarium of smoking cessation aids is available in the forms of nicotine replacement therapy (NRT), non ...
Shor, Chaya
core +1 more source
THE EFFECT OF NURSES' CHALLENGES TO STOPPING SMOKING ON NICOTINE ADDICTIONS
International Journal of Health Services Research and PolicyThis study was conducted to examine the effects of nurses' difficulties in quitting smoking and their socio-demographic characteristics on Nicotine addictions. A cross-sectional study was conducted between August and November 2022.
Ümmühan Aktürk +3 more
doaj +1 more source
Trace Amine-Associated Receptor 1 Modulates the Locomotor and Sensitization Effects of Nicotine
Frontiers in Pharmacology, 2018 Trace amine-associated receptor 1 (TAAR1) has emerged as a promising target for addiction treatments because it affects dopamine transmission in the mesolimbic pathway.
Ilya Sukhanov +7 more
doaj +1 more source
British Journal of Clinical Pharmacology, EarlyView.Abstract Cyclizine is a long‐established, short‐acting drug, registered for preventing motion sickness, post‐operative nausea and vomiting (PONV) and ‘vomiting of known cause’. The latter is not defined but may include pregnancy and patients receiving palliative care, historically accepted without large, controlled trials.
Gareth J. Sanger, Paul L. R. Andrews
wiley +1 more source