Results 21 to 30 of about 205,287 (293)
Nicotine binding and nicotinic receptor subunit RNA after chronic nicotine treatment [PDF]
The Journal of Neuroscience, 1992 DBA mice were chronically treated with nicotine by continuous intravenous infusion of 4.0 mg/kg/hr for 10 d. Drug-treated mice were tolerant to the acute effects of nicotine on locomotor activity and body temperature. The effect of chronic treatment on the amount of L-3H- nicotine binding and RNA encoding for alpha 4, the most widely expressed ...
M J, Marks +6 more
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Paying attention to smell: Cholinergic signaling in the olfactory bulb.
Frontiers in Synaptic Neuroscience, 2014 The tractable, layered architecture of the olfactory bulb (OB), and its function as a relay between odor input and higher cortical processing, makes it an attractive model to study how sensory information is processed at a synaptic and circuit level. The
Rinaldo David D'Souza +1 more
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Acetylcholine release and inhibitory interneuron activity in hippocampal CA1
Frontiers in Synaptic Neuroscience, 2014 Acetylcholine release in the central nervous system (CNS) has an important role in attention, recall and memory formation. One region influenced by acetylcholine is the hippocampus, which receives inputs from the medial septum and diagonal band of Broca ...
A. Rory McQuiston
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Role of the nicotinic acetylcholine receptor in Alzheimer's disease pathology and treatment.
Neuropharmacology, 2015 Alzheimer's Disease (AD) is the major form of senile dementia, characterized by neuronal loss, extracellular deposits, and neurofibrillary tangles. It is accompanied by a loss of cholinergic tone, and acetylcholine (ACh) levels in the brain, which were ...
S. Lombardo, U. Maskos
semanticscholar +1 more source
Biology, 2012 Unravelling the role of neuromessenger processes in learning and memory has long interested researchers. We investigated the effects of an acetylcholinesterase blocker, Methyl Parathion (MeP), on honeybee learning.
Shao-Wu Zhang, Hong Zhu, David Guez
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Nicotine vapor inhalation escalates nicotine self‐administration [PDF]
Addiction Biology, 2012 AbstractHumans escalate their cigarette smoking over time, and a major obstacle in the field of pre‐clinical nicotine addiction research has been the inability to produce escalated nicotine self‐administration in rats. In experiment 1, male Wistar rats were trained to respond for nicotine in 2‐hour operant sessions, then exposed to chronic intermittent
Nicholas W, Gilpin +5 more
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Nicotinic acid: a lipid-lowering agent with unrealized potential
The Egyptian Journal of Internal Medicine, 2014 Nicotinic acid is a well-known treatment for dyslipidemia in adults. This review article explored not only the role of nicotinic acid in dyslipidemia but also its role in hypertension and as a cardioprotective agent.
Samar H. Aboulsoud
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Bispyridinium Compounds Inhibit Both Muscle and Neuronal Nicotinic Acetylcholine Receptors in Human Cell Lines. [PDF]
PLoS ONE, 2015 Standard treatment of poisoning by organophosphorus anticholinesterases uses atropine to reduce the muscarinic effects of acetylcholine accumulation and oximes to reactivate acetylcholinesterase (the effectiveness of which depends on the specific ...
Avi Ring +8 more
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Cholinergic modulation in the vertebrate auditory pathway
Frontiers in Cellular NeuroscienceAcetylcholine (ACh) is a prevalent neurotransmitter throughout the nervous system. In the brain, ACh is widely regarded as a potent neuromodulator. In neurons, ACh signals are conferred through a variety of receptors that influence a broad range of ...
Chao Zhang, R. Michael Burger
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Journal of Animal Science and Technology, 2019 Vitamin B3 (niacin) is essential for all living cells and plays a central role in energy metabolism and oxidative phosphorylation. Vitamin B3, a water-soluble vitamin, is present in the form of nicotinic
Jale Çatak
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