Background Nicotinic and muscarinic acetylcholine receptors likely evolved in the cnidarian–bilaterian common ancestor. Both receptor families are best known for their role at chemical synapses in bilaterian animals, but they also have described roles as
Dylan Z. Faltine-Gonzalez+1 more
doaj +1 more source
Autoimmune T lymphocytes in myasthenia gravis. Determination of target epitopes using T lines and recombinant products of the mouse nicotinic acetylcholine receptor gene. [PDF]
Arthur Melms+6 more
openalex +1 more source
The regeneration of LC‐NE from pluripotent stem cells (PSCs) could significantly mitigate the progression of Neurodegenerative diseases and alleviate associated psychiatric disease symptoms, providing a new approach to the treatment of neurological diseases.
Yana Yang, Yunlong Tao
wiley +1 more source
Bacterial purine metabolism modulates C. elegans development and stress tolerance via DAF‐16
To investigate the impact of dietary components on animal growth, an Escherichia coli single‐gene deletion library was screened using the Caenorhabditis elegans growth model. Thirty‐four E. coli mutants were identified to delay worm development. Notably, E.
Min Feng+3 more
wiley +1 more source
Differential expression of nicotinic acetylcholine receptor genes in innervated and denervated chicken muscle. [PDF]
Stephen J. Moss+4 more
openalex +1 more source
The quest for the best target genes for RNAi‐mediated pest control
A major challenge for RNAi mediated pest control is the identification of the most effective RNAi target genes from the pool of ~37% of all genes that are essential. Effective RNAi target genes are predominantly highly conserved genes serving basic cellular functions such as protein degradation.
Doga Cedden, Gregor Bucher
wiley +1 more source
A single gene codes for the nicotinic acetylcholine receptor alpha-subunit in Torpedo marmorata: structural and developmental implications. [PDF]
André Klarsfeld+3 more
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ABSTRACT Background Chronic temporomandibular disorder (TMD) pain significantly impairs quality of life and lacks universally effective treatments. Antidepressants, traditionally used for mood disorders, have shown potential in managing chronic pain conditions.
Takara Dei+5 more
wiley +1 more source
Enteric neuropathy and the vagus nerve: Therapeutic implications
Abstract Enteric neuropathies are characterized by abnormalities of gut innervation, which includes the enteric nervous system, inducing severe gut dysmotility among other dysfunctions. Most of the gastrointestinal tract is innervated by the vagus nerve, the efferent branches of which have close interconnections with the enteric nervous system and ...
Bruno Bonaz
wiley +1 more source
Properties of monoclonal antibodies to nicotinic acetylcholine receptor from chick muscle [PDF]
Fuad Mehraban+2 more
openalex +1 more source