Results 31 to 40 of about 5,257,547 (397)

A novel α-conotoxin, PeIA, cloned from Conus pergrandis, discriminates between Rat α9α10 and α7 nicotinic cholinergic receptors [PDF]

open access: yes, 2005
The α9 and α10 nicotinic cholinergic subunits assemble to form the receptor believed to mediate synaptic transmission between efferent olivocochlear fibers and hair cells of the cochlea, one of the few examples of postsynaptic function for a non-muscle ...
Arredondo   +59 more
core   +1 more source

It takes two to tango: NAD+ and sirtuins in aging/longevity control [PDF]

open access: yes, 2016
The coupling of nicotinamide adenine dinucleotide (NAD+) breakdown and protein deacylation is a unique feature of the family of proteins called ‘sirtuins.’ This intimate connection between NAD+ and sirtuins has an ancient origin and provides a ...
Guarente, Leonard, Imai, Shin-ichiro
core   +2 more sources

Alpha9 nicotinic acetylcholine receptors and the treatment of pain [PDF]

open access: yes, 2009
Chronic pain is a vexing worldwide problem that causes substantial disability and consumes significant medical resources. Although there are numerous analgesic medications, these work through a small set of molecular mechanisms.
Absalom, Nathan   +4 more
core   +1 more source

EFFECTS OF GROSSHEMIN AND GROSSMISIN ON THE ACUTE HYPERLIPIDEMIA MODEL INDUCED BY ETHANOL

open access: yesБюллетень сибирской медицины, 2014
Objective: study sesquiterpene lactones grosshemin and grossmisin lipid-lowering properties on the model of acute hyperlipidemia induced by ethanol in rats.Materials and methods. Rats during 7 days injected into the stomach grosshemin and grossmisin in a
A. V. Ratkin   +5 more
doaj   +1 more source

Spectroscopic Characterization of Disulfiram and Nicotinic Acid after Biofield Treatment

open access: yes, 2015
Disulfiram is being used clinically as an aid in chronic alcoholism, while nicotinic acid is one of a B-complex vitamin that has cholesterol lowering activity.
M. Trivedi   +5 more
semanticscholar   +1 more source

Evaluation of the Effects of Nicotinic Acid and Folic Acid on Morphology, Membrane Integrity and Quality of Sperm Chromatin Concentration in Normozoospermic Men during Cryopreservation.

open access: yesمجله علمی دانشگاه علوم پزشکی کردستان, 2022
Background and Aim: Sperm cryopreservation is an important assisted reproductive technique. However, due to increased production of reactive oxygen species and oxidative stress, it can impair sperm function and reduce quality of fertility.
Raziah Hashemi   +5 more
doaj  

Venomous secretions from marine snails of the Terebridae family target acetylcholine receptors [PDF]

open access: yes, 2013
Venoms from cone snails (Conidae) have been extensively studied during the last decades, but those from other members of the suborder Toxoglossa, such as of Terebridae and Turridae superfamilies attracted less interest so far. Here, we report the effects
Kauferstein, Silke   +8 more
core   +3 more sources

Nicotinic Acid Metabolism

open access: yesJournal of Biological Chemistry, 1964
6-Hydroxynicotinic acid was demonstrated to be the first intermediate in the degradation of nicotinic acid by a clostridium. In the presence of pyruvate, other intermediates accumulated; two of these were identified, one as 1,4,5,6-tetrahydro-6-oxonicotinic acid, and the other as α-methyleneglutaric acid.
Ira Pastan, Earl R. Stadtman, L. Tsai
openaire   +5 more sources

Surface Interactions during the Removal of Emerging Contaminants by Hydrochar-Based Adsorbents

open access: yesMolecules, 2020
The aim of this work was to test activated carbons derived from hydrochars produced from sunflower stem, olive stone and walnut shells, as adsorbents for emerging contaminants in aqueous solution, namely fluoxetine and nicotinic acid.
Silvia Román   +4 more
doaj   +1 more source

Synthesis and characterization of ZnO/β-cyclodextrin/nicotinic acid nanocomposite and its biological and environmental application

open access: yesGreen Processing and Synthesis, 2023
In the present work, the disk-shaped zinc oxide (ZnO) nanoparticles were synthesized and functionalized with β-cyclodextrin (β-CD) and nicotinic acid (vitamin B3) using the wet co-precipitation method.
Alqahtani Mohammed S.   +3 more
doaj   +1 more source

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