Equilibrium Properties of Mouse-Torpedo Acetylcholine Receptor Hybrids Expressed in Xenopus Oocytes [PDF]
, 1987 This study used messenger RNA encoding each subunit (α, β, γ and δ) of the nicotinic acetylcholine (ACh) receptor from mouse BC3H-1 cells and from Torpedo electric organ.
Davidson, Norman +4 more
core +3 more sources
Bifidobacterium animalis subsp. lactis modulates early‐life immune response and gut metabolism
Animal Models and Experimental Medicine, EarlyView.Background: The maturation of the immune system is critical during early life, as it involves the differentiation, maturation, and establishment of immune tolerance of immune cells. This process is influenced not only by genetic factors but also by environmental factors, particularly the symbiotic microbiota. Bifidobacterium animalis subsp.
Haoming Du +17 more
wiley +1 more source
Interactions between the neuromodulatory systems and the amygdala: exploratory survey using the Allen Mouse Brain Atlas. [PDF]
, 2013 Neuromodulatory systems originate in nuclei localized in the subcortical region of the brain and control fundamental behaviors by interacting with many areas of the central nervous system.
Krichmar, Jeffrey L, Zaldivar, Andrew
core +1 more source
Biochemical Journal, 2005 SMCT (sodium-coupled monocarboxylate transporter; slc5a8) is a Na+-coupled transporter for lactate, pyruvate and short-chain fatty acids. Similar to these already known substrates of SMCT, the water-soluble B-complex vitamin nicotinic acid also exists as
E. Gopal +5 more
semanticscholar +1 more source
Untangling direct and domain-mediated interactions between nicotinic acetylcholine receptors in DHA-rich membranes [PDF]
arXiv, 2019 At the neuromuscular junction (NMJ), the nicotinic acetylcholine receptor (nAChR) self-associates to give rise to rapid muscle movement. While lipid domains have maintained nAChR aggregates in-vitro, their specific roles in nAChR clustering are currently unknown. In the present study, we carried out coarse-grained molecular dynamics simulations (CG-MD)
arxiv
Probing the role of the cation–π interaction in the binding sites of GPCRs using unnatural amino acids [PDF]
, 2009 We describe a general application of the nonsense suppression methodology for unnatural amino acid incorporation to probe drug–receptor interactions in functional G protein-coupled receptors (GPCRs), evaluating the binding sites of both the M2 muscarinic
Ballesteros +31 more
core +3 more sources
Docking Interaction of Protein Tyrosine Phosphatase and Complex Chromium(III) Nicotinate Compounds
Jurnal Kimia Valensi, 2017 Docking simulation is important in the process of drug design, mainly used for the prediction of interactions receptor(protein)–substrate. This study aims to understand the interaction between Chromium(III) nicotinate [Cr(O-nic)2(OH-) (H2O)3] and [Cr(N ...
Yuli Ambarwati +4 more
doaj +1 more source
Estimating the impact of treatment compliance over time on smoking cessation using data from ecological momentary assessments (EMA) [PDF]
arXiv, 2020 The Wisconsin Smoker's Health Study (WSHS2) was a longitudinal trial conducted to compare the effectiveness of two commonly used smoking cessation treatments, varenicline and combination nicotine replacement therapy (cNRT) with the less intense standard of care, nicotine patch.
arxiv
The kynurenine pathway and the brain: challenges, controversies and promises [PDF]
, 2017 Research on the neurobiology of the kynurenine pathway has suffered years of relative obscurity because tryptophan degradation, and its involvement in both physiology and major brain diseases, was viewed almost exclusively through the lens of the well ...
Schwarcz, Robert, Stone, Trevor W.
core +1 more source
A Cation–π Interaction between Extracellular TEA and an Aromatic Residue in Potassium Channels [PDF]
, 2006 Open-channel blockers such as tetraethylammonium (TEA) have a long history as probes of the permeation pathway of ion channels. High affinity blockade by extracellular TEA requires the presence of an aromatic amino acid at a position that sits at the ...
Ahern, Christopher A. +4 more
core +2 more sources