Results 131 to 140 of about 5,143,045 (401)

Rapid Analytical Method for Quantification of Gamma‐Hydroxybutyrate (GHB) in Hair by UPLC‐MS/MS

open access: yesDrug Testing and Analysis, EarlyView.
A rapid and simple UPLC‐MS/MS method for quantification of GHB in 10 mg of hair was developed. The method was satisfactorily validated, showing a linear range of 0.5–50 ng/mg, which allows us to quantify endogenous and exogenous GHB concentrations.
Miriam Blanco‐Ces   +5 more
wiley   +1 more source

Hot wires and film boiling: Another look at carbonyl formation in electronic cigarettes [PDF]

open access: yesarXiv, 2020
Electronic cigarettes (ECIGS) are a class of tobacco products that emit a nicotine-containing aerosol by heating and vaporizing a liquid. Apart from initiating nicotine addiction in nonsmokers, a persistent concern about these products is that their emissions often include high levels of carbonyl species, toxicants thought to cause most non-cancer ...
arxiv  

Two Amino Acid Residues Contribute to a Cation-π Binding Interaction in the Binding Site of an Insect GABA Receptor [PDF]

open access: yes, 2011
Cys-loop receptor binding sites characteristically possess an "aromatic box," where several aromatic amino acid residues surround the bound ligand. A cation-π interaction between one of these residues and the natural agonist is common, although the ...
Ashby, Jamie A.   +3 more
core  

Effect of nicotinic acid on rumen fermentation in vitro and in vivo.

open access: yesJournal of Dairy Science, 1980
A series of in vitro studies tested effects of nicotinic acid on rumen fermentation. Urea was the nitrogen supplement for all substances. As expected, a substrate of corn produced the most gas and microbial protein followed by a substrate of corn plus ...
D. O. Riddell, E. E. Bartley, A. Dayton
semanticscholar   +1 more source

Waxy‐ or Putty‐Like Materials as a Novel Drug Preparation for Synthetic Cannabinoid Receptor Agonists: Detection in Prisons and In Vitro Cannabinoid Receptor Activity

open access: yesDrug Testing and Analysis, EarlyView.
Waxy‐ or putty‐like materials has emerged as a novel drug preparation for synthetic cannabinoids and other drugs in UK prisons. An in vitro CB1 bioassay was used to evaluate the CB1 activating potential of MDMB‐INACA and extracts from eight seized samples. MDMB‐INACA had moderate efficacy but low potency at CB1.
Axelle Timmerman   +9 more
wiley   +1 more source

Bile Acids Induce Ca2+ Release from Both the Endoplasmic Reticulum and Acidic Intracellular Calcium Stores through Activation of Inositol Trisphosphate Receptors and Ryanodine Receptors*

open access: yesJournal of Biological Chemistry, 2006
Gallstones can cause acute pancreatitis, an often fatal disease in which the pancreas digests itself. This is probably because of biliary reflux into the pancreatic duct and subsequent bile acid action on the acinar cells.
J. Gerasimenko   +6 more
semanticscholar   +1 more source

Annual Banned‐Substance Review 17th Edition—Analytical Approaches in Human Sports Drug Testing 2023/2024

open access: yesDrug Testing and Analysis, EarlyView.
Scenarios of drug exposure and administration as well as detection assays for drugs and methods of sports doping published between 2023 and 2024 are critically reviewed and evaluated in context with the Prohibited List 2024 as established by the World Anti‐Doping Agency.
Mario  Thevis   +2 more
wiley   +1 more source

Metabolic abnormalities and reprogramming in cats with naturally occurring hypertrophic cardiomyopathy

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1256-1270, April 2025.
Abstract Background and aims The heart is a metabolic organ rich in mitochondria. The failing heart reprograms to utilize different energy substrates, which increase its oxygen consumption. These adaptive changes contribute to increased oxidative stress.
Qinghong Li   +12 more
wiley   +1 more source

Acid zeta function and ajoint acid zeta function [PDF]

open access: yesarXiv, 2010
In this paper we set up the theory of acid zeta function and ajoint acid zeta function, based on the theory, we point out a reason to doubt the truth of the Riemann hypothesis and also as a consequence, we give out some new RH equivalences.
arxiv  

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