Results 141 to 150 of about 41,031 (306)

The impact of dynamic kidney function prior to using sodium–glucose cotransporter‐2 inhibitors in type 2 diabetes patients with low‐risk renal disease progression

Journal of Diabetes Investigation, EarlyView.
ABSTRACT Aims/Introduction Few studies have assessed whether dynamic kidney function prior to sodium–glucose cotransporter‐2 inhibitor (SGLT2i) initiation influenced subsequent renal outcomes. Thus, the study aimed to investigate whether combining estimated glomerular filtration rate (eGFR) slope and urinary albumin/creatinine ratio (UACR) change prior
Yen‐Chen Chiu, Wanchana Singhan, Surarong Chinwong, Dujrudee Chinwong, Shang‐Jyh Hwang, Yaw‐Bin Huang   +5 more
wiley   +1 more source

The exposomal imprint on rosacea: More than skin deep

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Rosacea reflects systemic and environmental interactions, not just a skin disorder. Key factors include environmental triggers, genetic and microbiome influences, diagnostic gaps in skin of colour and social determinants. Advances in multi‐omics and exposome integration highlight pathways towards precision medicine, prevention and equitable, patient ...
Katerina Grafanaki, Daniella Bakoli Sgourou, Alexandros Maniatis, Efstathia Pasmatzi   +3 more
wiley   +1 more source

The effects of Nicotine on licking behavior induced by Apomorphine in rats

Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, 1999
Objective: The purpose of the present study was to determine the possible interaction of nicotine or muscarinic receptor mechanism(s) with the licking behavior induced by apomorphine in rats.
MR Zarrindast, M Shecharchi, M Rezayat
doaj  

Pharmacological Characterization of RJR‐2403: A Nicotinic Agonist with Potential Therapeutic Benefit in the Treatment of Alzheimer's Disease [PDF]

, 1997
Merouane Bencherif, Gary D. Byrd, William S. Caldwell, Jane Hayes, P M Lippiello   +4 more
openalex   +1 more source

Chronic Nicotine Selectively Enhances α4β2* Nicotinic Acetylcholine Receptors in the Nigrostriatal Dopamine Pathway [PDF]

, 2009
These electrophysiological experiments, in slices and intact animals, study the effects of in vivo chronic exposure to nicotine on functional α4β2* nAChRs in the nigrostriatal dopaminergic (DA) pathway.
Cai, Haijiang, Lester, Henry A., McIntosh, J. Michael, McKinney, Sheri, Nashmi, Raad, Xiao, Cheng   +5 more
core  

Substance Use and Problem Gambling Interventions for People With Intellectual Disability: A Systematic Review

Journal of Intellectual Disability Research, EarlyView.
ABSTRACT Introduction People with intellectual disability (ID) face increased vulnerability to addictive behaviours, yet effective interventions are under‐researched. This study aimed to systematically review existing interventions for substance use and problem gambling in this population. Methods Following PRISMA guidelines, we searched Web of Science,
Amalia Udeanu, Gloria Garcia‐Fernandez, Andrea Krotter, Juan Antonio García‐Aller, Patricia Solis Garcia, Laura E. Gómez   +5 more
wiley   +1 more source

Controversies in NEN: An ENETS position statement on nutritional support in neuroendocrine neoplasms

Journal of Neuroendocrinology, EarlyView.
Abstract Neuroendocrine neoplasms (NEN) themselves and also their treatment may cause malnutrition, inducing changes in physiological behaviour and eventually leading to increased rates of morbidity and mortality. Malnutrition is a common, under‐recognised and under‐treated condition in patients with NEN, and there are limited data available on the ...
Simona Grozinsky‐Glasberg, Johannes Hofland, Stephanie Alband, Yasmin Chotai de Lima, Adina Croitoru, Wanda Geilvoet, Peter Igaz, Beata Kos‐Kudła, Guenter J. Krejs, Alessandro Laviano, Francesco Panzuto, Anguraj Sadanandam, Ana Paula Santos, Staffan Welin, Rajaventhan Srirajaskanthan, V. Ambrosini, D. K. Bartsch, E. Baudin, N. Begum, E. Christ, J. Cros, T. Denecke, C. M. Deroose, C. Dromain, M. Falconi, N. Fazio, L. Fernandez‐Cuesta, R. Garcia‐Carbonero, A. Grossman, G. Kaltsas, A. Kasajima, A. Kjaer, G. Klöppel, U. P. Knigge, A. Lamarca, S. W. Langer, T. V. Luong, W. Martin, M. McNamara, D. O'Toole, S. Partelli, M. Pavel, A. Perren, R. Salazar, J. Schrader, H. Sorbye, A. Sowa‐Staszczak, E.‐J. Speel, P. Stalberg, M. Tesselaar, E. Tiensuu Janson, M. Tsoli, M. Volante, T. Walter   +53 more
wiley   +1 more source

Insights into channel function via channel dysfunction [PDF]

, 2003
The nicotinic synapse has been a touchstone for advances in neuroscience ever since Jean Nicot, the French ambassador to Portugal, sent some tobacco seeds home to Paris in 1550 with a note that the New World plant had interesting effects when smoked. Now
Leite, John F., Lester, Henry A., Rodrigues-Pinguet, Nivalda   +2 more
core  

Corticotropin‐releasing factor type 1 receptors in the rat nodose ganglion are involved in the transduction of stress‐induced visceral sensory signals to the brain

Journal of Neuroendocrinology, EarlyView.
Corticotropin‐releasing factor (CRF) and its type 1 receptor (CRF1) are expressed in the rat colon. The vagal nodose ganglion transmits visceral information to the brain; but whether the CRF/CRF1 system is involved in vagal afferent function remains unknown.
Asuka Mano‐Otagiri, Tamotsu Shibasaki, Atsushi Sakai, Yoshihiko Kakinuma   +3 more
wiley   +1 more source

Varenicline in the treatment of tobacco dependence

Neuropsychiatric Disease and Treatment, 2008
Karl Fagerström1, John Hughes21Smokers Information Centre, Fagerström Consulting AB, Berga Alle 1, 25452 Helsingborg, Sweden; 2University of Vermont, Burlington, Vermont, USAAbstract: Varenicline, a partial agonist of α4& ...
Karl Fagerström, John Hughes
doaj