Results 141 to 150 of about 2,143 (224)
Models of the extracellular domain of the nicotinic receptors and of agonist- and Ca 2+ -binding sites [PDF]
, 2002 Nicolas Le Novère +2 more
openalex +1 more source
Addiction, Volume 120, Issue 5, Page 813-834, May 2025.Abstract Background and Aims Substance use disorders (SUD) lead to a high burden of disease, yet treatment options are limited. Cannabidiol (CBD) is being investigated as a potential therapeutic target due to its pharmacological properties and mode of action in the endocannabinoid system.
Bertrand Redonnet +4 more
wiley +1 more source
Pathobiology and Regulation of Eosinophils, Mast Cells, and Basophils in Allergic Asthma
Immunological Reviews, Volume 331, Issue 1, May 2025.ABSTRACT Eosinophilia is a hallmark of allergic disorders, including asthma, allergic rhinitis, and atopic dermatitis. The onset and maintenance of allergic inflammation in atopic adults involves the activation of selective hemopoietic processes and the migration of mature and immature eosinophils to allergic tissue, where these cells release mediators
Christiane E. Whetstone +4 more
wiley +1 more source
Autocrine negative feedback regulation of lipolysis through sensing of NEFAs by FFAR4/GPR120 in WAT
Molecular Metabolism, 2020 Objectives: Long-chain fatty acids (LCFAs) released from adipocytes inhibit lipolysis through an unclear mechanism. We hypothesized that the LCFA receptor, FFAR4 (GPR120), which is highly expressed in adipocytes, may be involved in this feedback ...
Anna Sofie Husted +13 more
doaj
Advances in Fecal Microbiota Transplantation for Gut Dysbiosis‐Related Diseases
Advanced Science, Volume 12, Issue 13, April 3, 2025.This article reviews the use of fecal microbiota transplantation (FMT) to treat intestinal diseases like recurrent Clostridioides difficile infection (rCDI), inflammatory bowel disease (IBD), and irritable bowel syndrome (IBS). It discusses FMT's efficacy, influencing factors such as donor selection, recipient characteristics, and treatment protocols ...
Shuna Hou +4 more
wiley +1 more source
Advanced Science, Volume 12, Issue 15, April 17, 2025.Graphic illustration showing the strategic approaches based on the currently investigated evidence of psychedelics that suggests the challenges and how to address the prescription of mental disorders. These applicable avenues may provide substantial insight into distinguishing between brain networks and psychedelics.
Sung‐Hyun Kim +5 more
wiley +1 more source
Repeated Administration of the GABAB Receptor Agonist CGP44532 Decreased Nicotine Self-Administration, and Acute Administration Decreased Cue-Induced Reinstatement of Nicotine-Seeking in Rats [PDF]
, 2004 Neil E. Paterson +2 more
openalex +1 more source
Journal of Cachexia, Sarcopenia and Muscle, Volume 16, Issue 2, April 2025.ABSTRACT Background Muscle wasting (MW) of burn injury (BI) remains unresolved. Microglia‐mediated inflammatory cytokine/chemokine release, motor neuron loss (MNL) and MW is observed after BI but connection of the central changes to synaptic‐denervation and MW is unelucidated.
Jingyuan Chen +7 more
wiley +1 more source