European Guideline on Chronic Nausea and Vomiting—A UEG and ESNM Consensus for Clinical Management
United European Gastroenterology Journal, Volume 13, Issue 3, Page 427-471, April 2025.ABSTRACT Introduction Chronic nausea and vomiting are symptoms of a wide range of gastrointestinal and non‐gastrointestinal conditions. Diagnosis can be challenging and requires a systematic and well‐structured approach. If the initial investigation for structural, toxic and metabolic disorders is negative, digestive motility and gut‐brain interaction ...
Carolina Malagelada +34 more
wiley +1 more source
Invariant Aspartic Acid in Muscle Nicotinic Receptor Contributes Selectively to the Kinetics of Agonist Binding [PDF]
, 2004 Won Yong Lee, Steven M. Sine
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British Journal of Clinical Pharmacology, Volume 91, Issue 4, Page 1132-1156, April 2025.Abstract Structured medication reviews (SMRs) were introduced into the National Health Service (NHS) Primary Care to support the delivery of the NHS Long‐Term Plan for medicines optimization. SMRs improve the quality of care, reduce harm and offer value for money. However, evidence to support SMRs for patients with chronic kidney disease (CKD) stage G4‐
Cathy Margaret Pogson +3 more
wiley +1 more source
Ex vivo receptor occupation of GTS-21, a novel nicotinic receptor agonist, in rats.
, 1996 Yoshihisa Nozawa +4 more
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The characterization of a novel rigid nicotine analog with α7-selective nAChR agonist activity and modulation of agonist properties by boron inclusion [PDF]
, 2005 Roger L. Papke +4 more
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Advances in PET Imaging of α7 Nicotinic Receptors: From Radioligand Development to CNS Applications
Basic &Clinical Pharmacology &Toxicology, Volume 136, Issue 4, April 2025.ABSTRACT Positron emission tomography (PET) has significantly advanced our understanding of the brain by enabling non‐invasive imaging and quantification of molecular processes, including receptor binding. In this review, we explore the development and application of PET radioligands targeting the α7 nicotinic acetylcholine receptor (α7 nAChR), a ...
Janus H. Magnussen
wiley +1 more source
Modulation of airway inflammation and resistance in mice by a nicotinic receptor agonist [PDF]
, 2005 M-R. Blanchet +2 more
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Ghrelin: An Emerging Therapy for Heart Failure
Clinical Endocrinology, Volume 102, Issue 4, Page 403-412, April 2025.ABSTRACT Objective Ghrelin is emerging as a promising therapeutic option for heart failure (HF) due to its potent inotropic, anabolic, and cardioprotective properties. This review aims to critically examine the available clinical evidence on ghrelin therapy in HF, while also incorporating key findings from preclinical studies that support its ...
Nikolaos Theodorakis +6 more
wiley +1 more source
Efficacy of Varenicline, an α4β2 Nicotinic Acetylcholine Receptor Partial Agonist, vs Placebo or Sustained-Release Bupropion for Smoking Cessation: A Randomized Controlled Trial—Correction [PDF]
, 2006 openalex +1 more source