Isoflurane Increases the Apparent Agonist Affinity of the Nicotinic Acetylcholine Receptor by Reducing the Microscopic Agonist Dissociation Constant [PDF]
, 2000 Douglas E. Raines, Vinu T. Zachariah
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British Journal of Pharmacology, Volume 182, Issue 13, Page 2950-2967, July 2025.Background and Purpose Platelet function during inflammation is dependent on activation by endogenous nucleotides acting on purinergic receptors. The P2Y14 receptor has been reported to be expressed on platelets and is involved in leukocyte recruitment during inflammation.
Md Monir Hossain +6 more
wiley +1 more source
Preclinical Pharmacology of ABT‐594: A Nicotinic Acetylcholine Receptor Agonist for the Treatment of Pain [PDF]
, 2000 Michael D. Meyer +6 more
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Agonist Selectivity and Ion Permeation in the α3β4 Ganglionic Nicotinic Receptor
Neuron, 2019 A. Gharpure +9 more
semanticscholar +1 more source
Contributions of Torpedo Nicotinic Acetylcholine Receptor γTrp-55 and δTrp-57 to Agonist and Competitive Antagonist Function [PDF]
, 2001 Yu Xie, Jonathan B. Cohen
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Two Amino Acid Residues Contribute to a Cation-π Binding Interaction in the Binding Site of an Insect GABA Receptor [PDF]
, 2011 Cys-loop receptor binding sites characteristically possess an "aromatic box," where several aromatic amino acid residues surround the bound ligand. A cation-π interaction between one of these residues and the natural agonist is common, although the ...
Ashby, Jamie A. +3 more
core
Models of the extracellular domain of the nicotinic receptors and of agonist- and Ca 2+ -binding sites [PDF]
, 2002 Nicolas Le Novère +2 more
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Advanced Functional Materials, Volume 35, Issue 23, June 5, 2025.Ultrathin, flexible neural probes are developed with an innovative, biomimetic design incorporating brain tissue‐compatible materials. The material system employs biomolecule‐based encapsulation agents to mitigate inflammatory responses, as demonstrated through comprehensive in vitro and in vivo studies.
Jeonghwa Jeong +7 more
wiley +1 more source
Autocrine negative feedback regulation of lipolysis through sensing of NEFAs by FFAR4/GPR120 in WAT
Molecular Metabolism, 2020 Objectives: Long-chain fatty acids (LCFAs) released from adipocytes inhibit lipolysis through an unclear mechanism. We hypothesized that the LCFA receptor, FFAR4 (GPR120), which is highly expressed in adipocytes, may be involved in this feedback ...
Anna Sofie Husted +13 more
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