Effects of the nicotinic agonist varenicline, nicotinic antagonist r-bPiDI, and DAT inhibitor (R)-modafinil on co-use of ethanol and nicotine in female P rats. [PDF]
Psychopharmacology (Berl), 2018 Maggio SE +11 more
europepmc +1 more source
Efficacy of Varenicline, an α4β2 Nicotinic Acetylcholine Receptor Partial Agonist, vs Placebo or Sustained-Release Bupropion for Smoking Cessation: A Randomized Controlled Trial—Correction [PDF]
, 2006 openalex +1 more source
British Journal of Pharmacology, Volume 182, Issue 21, Page 5286-5302, November 2025.Abstract Background and purpose Positive allosteric modulation of the P2X4 receptor is a potential route to providing cardiovascular benefit through enhancing flow‐dependent arterial vasodilation and providing cardioprotection. However, ligands that selectively enhance P2X4 activity are absent.
Jessica L. Meades +4 more
wiley +1 more source
Innate Immunity and Inflammation Post-Stroke: An α7-Nicotinic Agonist Perspective. [PDF]
Int J Mol Sci, 2015 Neumann S +4 more
europepmc +1 more source
Diabetes, Obesity and Metabolism, Volume 27, Issue 11, Page 6188-6199, November 2025.Abstract Aims To evaluate whether initiating sodium‐glucose cotransporter 2 inhibitors (SGLT2i) within 3 months after a urinary tract infection (UTI) is associated with improved long‐term outcomes in patients with type 2 diabetes mellitus (T2DM), compared with dipeptidyl peptidase‐4 inhibitors (DPP‐4i).
Hsiao‐Wei Wang +5 more
wiley +1 more source
Drug, Healthcare and Patient Safety, 2010 Zheng-Xiong XiNational Institute on Drug Abuse, Intramural Research Program, Baltimore, MD, USAAbstract: Smoking is still the most prominent cause of preventable premature death in the United States and an increasing cause of morbidity and mortality ...
Zheng-Xiong Xi
doaj
Neuroendocrinology meets addiction: Emerging pharmacotherapies on the horizon
Journal of Internal Medicine, Volume 298, Issue 5, Page 392-423, November 2025.Abstract Alcohol and other substance use disorders (ASUDs) are prevalent and major contributors to global morbidity and mortality. Their impact extends beyond the individual, imposing significant burdens on families, communities, healthcare systems, and society at large.
Anna Loften +3 more
wiley +1 more source
Effect of ABT-594 a Selective Nicotinic Agonist, on Voiding Function in Spinal Cord Injury Rat [PDF]
, 2006 Hyun Rho, Sun-Ju Lee, Sung‐Goo Chang
openalex +1 more source
Liver International, Volume 45, Issue 11, November 2025.ABSTRACT Background Alcohol‐associated liver disease (ALD) is a leading cause of liver‐related morbidity and mortality, yet effective therapeutic options remain limited. Preclinical data suggest that modulation of the hepatic endocannabinoid system, particularly via cannabidiol (CBD), may reduce alcohol‐induced liver injury.
Butros Fakhoury +6 more
wiley +1 more source
Nicotinic α5 subunit deletion locally reduces high‐affinity agonist activation without altering nicotinic receptor numbers [PDF]
, 2007 R.W. Brown +3 more
openalex +1 more source