Effects of the nicotinic agonist varenicline, nicotinic antagonist r-bPiDI, and DAT inhibitor (R)-modafinil on co-use of ethanol and nicotine in female P rats. [PDF]
Maggio SE+11 more
europepmc +1 more source
This research indicates that enhanced purine metabolism and disrupted arginine metabolism contribute to the nicotine withdrawal‐induced anxiety and depression‐like behaviours in the cerebellum. Treatment with theobromine markedly alleviates these behaviours.
Wenjuan Zhang+6 more
wiley +1 more source
Evaluation of Agonist and Antagonist Activities against Nicotinic Acetyicholine Receptors
Kazuhiko Matsuda
openalex +2 more sources
Nicotinic Acid Receptor Agonists Differentially Activate Downstream Effectors [PDF]
Jeremy G. Richman+17 more
openalex +1 more source
Plant‐derived compounds such as polyphenols, flavonoids, alkaloids, and terpenoids exhibit neuroprotective, antioxidant, and anti‐inflammatory activities in Parkinson's disease models. Unlike levodopa, they provide disease‐modifying benefits by targeting α‐synuclein aggregation, mitochondrial dysfunction, and neuroinflammation.
Emre Aktaş+2 more
wiley +1 more source
A structural model of agonist binding to the α3β4 neuronal nicotinic receptor
Valéria Catelli Infantozzi Costa+3 more
openalex +1 more source
Nicotinic α5 subunit deletion locally reduces high‐affinity agonist activation without altering nicotinic receptor numbers [PDF]
R.W. Brown+3 more
openalex +1 more source
Polymeric nanoparticles represent promising drug (gene) delivery carriers to the brain due to their unique advantages to facilitate the penetration of blood–brain barrier and endocytosis of neuronal cells in neurodegenerative diseases. ABSTRACT In spite of great advances in modern medicine, there are a few effective strategies for the treatment of ...
Lian Jin+4 more
wiley +1 more source
Volatile Anesthetics Reduce Agonist Affinity at Nicotinic Acetylcholine Receptors in the Brain
Erin M. Rada+2 more
openalex +1 more source
Antilipolytic Activity of a Novel Partial A1Adenosine Receptor Agonist Devoid of Cardiovascular Effects: Comparison with Nicotinic Acid [PDF]
Arvinder K. Dhalla+5 more
openalex +1 more source