Results 211 to 220 of about 484,958 (335)

Effects of the nicotinic agonist varenicline, nicotinic antagonist r-bPiDI, and DAT inhibitor (R)-modafinil on co-use of ethanol and nicotine in female P rats. [PDF]

open access: yesPsychopharmacology (Berl), 2018
Maggio SE   +11 more
europepmc   +1 more source

Arginine Metabolism and Adenosine Receptor Signals in the Cerebellum Contribute to Nicotine Withdrawal‐Induced Anxiety/Depression‐Like Behaviours

open access: yesAddiction Biology, Volume 30, Issue 8, August 2025.
This research indicates that enhanced purine metabolism and disrupted arginine metabolism contribute to the nicotine withdrawal‐induced anxiety and depression‐like behaviours in the cerebellum. Treatment with theobromine markedly alleviates these behaviours.
Wenjuan Zhang   +6 more
wiley   +1 more source

Nicotinic Acid Receptor Agonists Differentially Activate Downstream Effectors [PDF]

open access: hybrid, 2007
Jeremy G. Richman   +17 more
openalex   +1 more source

Levodopa and Plant‐Derived Bioactive Compounds in Parkinson's Disease: Mechanisms, Efficacy, and Future Perspectives

open access: yesCNS Neuroscience &Therapeutics, Volume 31, Issue 8, August 2025.
Plant‐derived compounds such as polyphenols, flavonoids, alkaloids, and terpenoids exhibit neuroprotective, antioxidant, and anti‐inflammatory activities in Parkinson's disease models. Unlike levodopa, they provide disease‐modifying benefits by targeting α‐synuclein aggregation, mitochondrial dysfunction, and neuroinflammation.
Emre Aktaş   +2 more
wiley   +1 more source

A structural model of agonist binding to the α3β4 neuronal nicotinic receptor

open access: green, 2003
Valéria Catelli Infantozzi Costa   +3 more
openalex   +1 more source

The Application of Polymeric Nanoparticles as Drug Delivery Carriers to Cells in Neurodegenerative Diseases

open access: yesCell Proliferation, Volume 58, Issue 8, August 2025.
Polymeric nanoparticles represent promising drug (gene) delivery carriers to the brain due to their unique advantages to facilitate the penetration of blood–brain barrier and endocytosis of neuronal cells in neurodegenerative diseases. ABSTRACT In spite of great advances in modern medicine, there are a few effective strategies for the treatment of ...
Lian Jin   +4 more
wiley   +1 more source

Antilipolytic Activity of a Novel Partial A1Adenosine Receptor Agonist Devoid of Cardiovascular Effects: Comparison with Nicotinic Acid [PDF]

open access: green, 2007
Arvinder K. Dhalla   +5 more
openalex   +1 more source

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