Results 181 to 190 of about 34,485 (247)

GLP‐1 Receptor Agonist Therapy and Cardiorenal Outcomes in Patients ≥ 80 Years Old With Type 2 Diabetes

Journal of the American Geriatrics Society, Volume 74, Issue 1, Page 96-106, January 2026.
Effect of glucagon‐like peptide‐1 receptor agonist therapy on cardiorenal outcomes in patients aged ≥ 80 years with Type 2 diabetes. ABSTRACT Background Glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) have demonstrated potential in improving glycemic control and reducing adverse outcomes in patients with Type 2 diabetes mellitus (T2DM); however ...
Jui‐Cheng Chen, Yu‐Wei Fang, Ya‐Fang Liu, Mon‐Ting Chen, Ming‐Hsien Tsai   +4 more
wiley   +1 more source

Modulation of Master Transcription Factor Expression of Nile Tilapia Leukocytes via Cholinergic Pathways. [PDF]

Int J Mol Sci
Girón-Pérez MI, Ramírez-Ibarra KM, Covantes-Rosales CE, Girón-Pérez DA, Razura-Carmona FF, Contis-Montes de Oca A, Morales-Montor J, Pavón L, Toledo-Ibarra GA.   +8 more
europepmc   +1 more source

Effectiveness of nicotinic agonists as desensitizers at presynaptic α4β2- and α4α5β2-nicotinic acetylcholine receptors. [PDF]

Nicotine Tob Res, 2014
Wageman CR, Marks MJ, Grady SR.
europepmc   +1 more source

Neurons in a Dish: A Review of In Vitro Cell Models for Studying Neurogenesis

Journal of Neurochemistry, Volume 170, Issue 1, January 2026.
Different in vitro cell models are valuable to study the different steps of neurogenesis, from the proliferation of neural stem and progenitor cells to the maturation of neurons. Pluripotent stem cells (including embryonic stem cells and induced pluripotent stem cells), immortalized human neuroblastoma cell lines (SH‐SY5Y, IMR‐32), and primary brain ...
Mariana Vassal, Ana C. Cruz, Sandra Rebelo, Filipa Martins   +3 more
wiley   +1 more source

Selective α7 nicotinic acetylcholine receptor agonists worsen disease in experimental colitis [PDF]

, 2010
Susanne A. Snoek, Marleen I. Verstege, Esmerij P. van der Zanden, Nigel Deeks, David C. Bulmer, Michael J. Skynner, Kevin Lee, Anje A. te Velde, Guy E. Boeckxstaens, Wouter J. de Jonge   +9 more
openalex   +1 more source

Nicotine Regulates LPS‐Induced Inflammatory Responses in HMC3 Microglia and Exerts Neuronal Protection

Mediators of Inflammation, Volume 2026, Issue 1, 2026.
Microglia‐mediated neuroimmune responses have been implicated in central nervous system injury and disease pathogenesis. The α7 nicotinic acetylcholine receptor (α7 nAChR), which is expressed on microglia and participates in microenvironment interactions, is a key mediator of the cholinergic anti‐inflammatory pathway.
Yuhan Qin, Xiaohui Yan, Yanbo Luo, Hongjuan Wang, Yushan Tian, Xiaqing Wu, Huan Chen, Hongwei Hou, Qingyuan Hu, Jasbir Arora (RSS)   +9 more
wiley   +1 more source

The Central Cholinergic Synapse: A Primer. [PDF]

Int J Mol Sci
Klein J.
europepmc   +1 more source

Glucagon‐Like Peptide‐1 Receptor Agonists Are Associated With Improved Outcomes in Inflammatory Bowel Disease

GastroHep, Volume 2026, Issue 1, 2026.
Background The co‐existence of diabetes and obesity in patients with inflammatory bowel disease (IBD) increases morbidity and mortality associated with IBD, yet it remains unclear how medications used to treat these metabolic disorders affect IBD course.
Michael Saadeh, Apoorva Krishna Chandar, Revital Gorodeski Baskin, Jeffry Katz, Fabio Cominelli, Emad Mansoor, Miguel Regueiro, Vu Quang Nguyen, Than Than Aye   +8 more
wiley   +1 more source

Neuroprotective effects of a nicotinic acetylcholine receptor agonist and modulator in the rodent retina

, 2011
Kazuhiro Iwamoto
openalex   +1 more source

Expeditious Synthesis, Enantiomeric Resolution, and Enantiomer Functional Characterization of (4-(4-Bromophenyl)-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-8-sulfonamide (4BP-TQS): An Allosteric Agonist-Positive Allosteric Modulator of α7 Nicotinic Acetylcholine Receptors

, 2013
Ganesh A. Thakur, Abhijit Kulkarni, Jeffrey R. Deschamps, Roger L. Papke   +3 more
openalex   +1 more source