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Nicotinic receptors [PDF]

, 2014
Regulation of normal or abnormal behaviour is critically controlled by the central serotonergic systems. Recent evidence has suggested that serotonin (5-HT) neurotransmission dysfunction contributes to a variety of pathological conditions, including ...
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Nicotinic acetylcholine receptors [PDF]

British Journal of Pharmacology, 2018
This themed section of the British Journal of Pharmacology is the product of a conference that focussed on nicotinic ACh receptors (nAChRs) that was held on the Greek island of Crete from 7 to 11 May 2017. ‘Nicotinic acetylcholine receptors 2017’ was the fourth in a series of triennial international meetings that have provided a regular forum for ...
Wonnacott, S, Bermudez, I, Millar, NS, Tzartos, SJ   +3 more
openaire   +3 more sources

Cloning and characterization of the hamster and guinea pig nicotinic acid receptors

Journal of Lipid Research, 2007
In this study, we present the identification and characterization of hamster and guinea pig nicotinic acid receptors. The hamster receptor shares ∼80–90% identity with the nucleotide and amino acid sequences of human, mouse, and rat receptors. The guinea
April Smith Torhan, Boonlert Cheewatrakoolpong, Lia Kwee, Scott Greenfeder   +3 more
doaj   +1 more source

Curiouser and Curiouser: The Macrocyclic Lactone, Abamectin, Is also a Potent Inhibitor of Pyrantel/Tribendimidine Nicotinic Acetylcholine Receptors of Gastro-Intestinal Worms. [PDF]

PLoS ONE, 2016
Nematode parasites may be controlled with drugs, but their regular application has given rise to concerns about the development of resistance. Drug combinations may be more effective than single drugs and delay the onset of resistance.
Melanie Abongwa, Samuel K Buxton, Alan P Robertson, Richard J Martin   +3 more
doaj   +1 more source

Nicotine-Induced Effects on Nicotinic Acetylcholine Receptors (nAChRs), Ca2+ and Brain-Derived Neurotrophic Factor (BDNF) in STC-1 Cells [PDF]

, 2016
In addition to the T2R bitter taste receptors, neuronal nicotinic acetylcholine receptors (nAChRs) have recently been shown to be involved in the bitter taste transduction of nicotine, acetylcholine and ethanol.
Alkahtan, Reem M., Grider, John R., Lyall, Vijay, Mahavadi, Sunila, Mummalaneni, Shobha K., Murthy, Karnam S., Qian, Jie   +6 more
core   +3 more sources

Expression and function of nicotinic acetylcholine receptors in stem cells

AIMS Bioengineering, 2016
Nicotinic acetylcholine receptors are prototypical ligand gated ion channels typically found in muscular and neuronal tissues. Functional nicotinic acetylcholine receptors, however, have also recently been identified on other cell types, including stem ...
Herman S. Cheung, Jordan M. Greenberg, Carlos M. Carballosa   +2 more
doaj   +1 more source

NICOTINIC RECEPTORS IN NEUROPSYCHIATRIC PATHOLOGIES OF ADULTHOOD AND DEVELOPMENTAL AGE. [PDF]

Euromediterranean Biomedical Journal, 2013
Nicotinic acetylcholine receptors (nAChRs) are ligand-gated ion channels present in many regions of the central nervous system (CNS) and the peripheral nervous system.
Elettra Unti
doaj   +1 more source

Signaling of nicotinic acetylcholine receptors in mononuclear phagocytes

Pharmacological Research, 2023
Nicotinic acetylcholine receptors are not only expressed by the nervous system and at the neuro-muscular junction but also by mononuclear phagocytes, which belong to the innate immune system.
Katrin Richter, Veronika Grau
doaj   +1 more source

Live-Cell Imaging of Single Receptor Composition Using Zero-Mode Waveguide Nanostructures [PDF]

, 2012
We exploit the optical and spatial features of subwavelength nanostructures to examine individual receptors on the plasma membrane of living cells. Receptors were sequestered in portions of the membrane projected into zero-mode waveguides.
Dougherty, Dennis A., Korlach, Jonas, Lester, Henry A., Luong, Khai, Richards, Christopher I., Srinivasan, Rahul, Turner, Stephen W.   +6 more
core   +1 more source

Acetylcholine release in mouse hippocampal CA1 preferentially activates inhibitory-selective interneurons via alpha4 beta2* nicotinic receptor activation

Frontiers in Cellular Neuroscience, 2015
Acetylcholine (ACh) release onto nicotinic receptors directly activates subsets of inhibitory interneurons in hippocampal CA1. However, the specific interneurons activated and their effect on the hippocampal network is not completely understood ...
L. Andrew Bell, Karen A. Bell, Rory eMcquiston   +2 more
doaj   +1 more source